Abdominal aortic aneurysm

Common Name(s)

Abdominal aortic aneurysm

An abdominal aortic aneurysm (AAA) is when the lower part of the aorta becomes enlarged, like a balloon. The aorta is the largest artery in the body. It carries blood from the heart down along the backbone where it splits into many smaller arteries that bring blood to all of the organs. Aneurysm is a general term that describes an enlargement of any blood vessel in the body. Aneurysms usually develop slowly over time and may not cause problems until they become so enlarged that they can rupture.

Smaller AAAs generally do not cause symptoms. Larger AAAs can cause symptoms such as a pulsating feeling near the belly button, deep and constant abdominal pain, or back pain. Rupture of an aortic aneurysm is a medical emergency. If an aortic aneurysm ruptures, symptoms include vomiting, intense pain, excessive sweating, a drop in blood pressure, fainting, and shortness of breath.

AAAs can be caused by stiffening of the artery walls due to plaque build up (atherosclerosis), infection of the aorta, or connective tissue diseases. Risk factors for the development of AAAs are increased in individuals who smoke, are male, or have a family history of aneurysms.

A doctor can perform many tests to diagnose this condition. Possible tests include imaging by abdominal ultrasound, chest X-ray, and MRI. Treatment options will vary depending on the size of the aneurysm. For smaller aneurysms, it may be better to wait and watch before seeking surgery. For larger aneurysms that are at risk of rupturing, surgery is usually the best treatment. Talk to your doctor about which of the current treatment options is right for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal aortic aneurysm" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal aortic aneurysm" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Abdominal aortic aneurysm" returned 1642 free, full-text research articles on human participants. First 3 results:

Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm.
 

Author(s): Tong Jiao, Ye Yao, Bo Zhang, Da-Cheng Hao, Qing-Feng Sun, Jing-Bo Li, Chao Yuan, Bao Jing, Yun-Peng Wang, Hai-Yang Wang

Journal: Biomed Res Int. 2017 ;2017():9645874.

 

MicroRNAs (miRNAs) are deregulated in various vascular ailments including abdominal aortic aneurysm (AAA). MiR-103 is involved in vascular, metabolic, and malignant diseases, but whether it participates in the pathogenesis of AAA remains elusive. ADAM10 plays a vital role in the formation ...

Last Updated: 30 Mar 2017

Go To URL
Fluid-Structure Interaction in Abdominal Aortic Aneurysm: Effect of Modeling Techniques.
 

Author(s): Shengmao Lin, Xinwei Han, Yonghua Bi, Siyeong Ju, Linxia Gu

Journal: Biomed Res Int. 2017 ;2017():7023078.

 

In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics ...

Last Updated: 21 Mar 2017

Go To URL
Abdominal Aortic Aneurysm Repair in England and the United States.
 

Author(s): Frank A Lederle

Journal: N. Engl. J. Med.. 2017 03;376(10):998.

 

Last Updated: 8 Mar 2017

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Abdominal aortic aneurysm" returned 152 free, full-text review articles on human participants. First 3 results:

Extended use of endovascular aneurysm sealing for ruptured abdominal aortic aneurysms.
 

Author(s): Dittmar Böckler, Andrew Holden, Dainis Krievins, Jean-Paul P M de Vries, Andreas S Peters, Philipp Geisbüsch, Michel Reijnen

Journal: Semin Vasc Surg. 2016 Sep;29(3):106-113.

 

Endovascular repair of abdominal aortic aneurysms (EVAR) is now an established treatment modality for suitable patients presenting with aneurysm rupture. EVAR for ruptured aneurysms reduces transfusion, mechanical ventilation, intensive care. and hospital stay when compared with open ...

Last Updated: 19 Dec 2016

Go To URL
Association between MTHFR C677T polymorphism and abdominal aortic aneurysm risk: A comprehensive meta-analysis with 10,123 participants involved.
 

Author(s): Jie Liu, Xin Jia, Haifeng Li, Senhao Jia, Minhong Zhang, Yongle Xu, Xin Du, Nianrong Zhang, Weihang Lu, Wei Guo

Journal: Medicine (Baltimore). 2016 Sep;95(36):e4793.

 

Abdominal aortic aneurysm (AAA) is a life-threatening condition. A number of studies reported the association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and AAA risk, but substantial controversial findings were observed and the strength of the association remains unclear.

Last Updated: 8 Sep 2016

Go To URL
The Potential Role of Kallistatin in the Development of Abdominal Aortic Aneurysm.
 

Author(s): Jiaze Li, Smriti Murali Krishna, Jonathan Golledge

Journal:

 

Abdominal aortic aneurysm (AAA) is a vascular condition that causes permanent dilation of the abdominal aorta, which can lead to death due to aortic rupture. The only treatment for AAA is surgical repair, and there is no current drug treatment for AAA. Aortic inflammation, vascular ...

Last Updated: 17 Aug 2016

Go To URL
 
 
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Study of the Treovance Stent-Graft for Patients With Abdominal Aortic Aneurysms
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm (AAA)

 

Last Updated: 21 Aug 2015

Go to URL
Sodium Fluoride Imaging of Abdominal Aortic Aneurysms
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm

 

Last Updated: 25 Oct 2016

Go to URL