Achalasia

Common Name(s)

Achalasia

Achalasia is a disorder of the esophagus, the tube that carries food from the mouth to the stomach.  It is characterized by enlargement of the esophagus, impaired ability of the esophagus to push food down toward the stomach (peristalsis), and failure of the ring-shaped muscle at the bottom of the esophagus (the lower esophageal sphincter) to relax.  Achalasia is caused by damage to the nerves of the esophagus. Treatment is aimed at reducing the pressure at the lower esophageal sphincter and may include Botox, medications, or surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Achalasia" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Achalasia" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Achalasia" returned 404 free, full-text research articles on human participants. First 3 results:

Obstructive bronchitis and recurrent pneumonia in esophageal achalasia in a child: A CARE compliant case report.
 

Author(s): Alexandr Evgen'evich Mashkov, Dmitrii Anatolèvich Pykchteev, Alexandr Viktorovic Sigachev, Andrei Viktorovich Bobylev, Johannes Michael Mayr

Journal: Medicine (Baltimore). 2018 Jun;97(23):e11016.

 

Esophageal achalasia is characterized by impaired relaxation of the cardia and dilation of the intrathoracic part of the esophagus. We describe the late presentation of achalasia in an 11-year old girl.

Last Updated: 31 Dec 1969

Go To URL
Retrograde gastroesophageal intussusception after peroral endoscopic myotomy in a patient with achalasia cardia: A case report.
 

Author(s): Samiullah Khan, Shuai Su, Kui Jiang, Bang-Mao Wang

Journal: Medicine (Baltimore). 2018 Jan;97(2):e9609.

 

Retrograde gastroesophageal intussusception (RGEI) is a relatively rare gastrointestinal (GI) disorder in which a portion of the stomach wall invaginates into the esophagus. More recently, peroral endoscopic myotomy (POEM) has emerged as an endoscopic alternative to surgical myotomy ...

Last Updated: 31 Dec 1969

Go To URL
Achalasia subtype differences based on clinical symptoms, radiographic findings, and stasis scores.
 

Author(s): M A Valdovinos Díaz

Journal: Rev Gastroenterol Mex. ;83(1):1-2.

 

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Achalasia" returned 58 free, full-text review articles on human participants. First 3 results:

High Resolution Manometry - A Mandatory Examination in the Pre and Postoperative Assessment of Patients with Achalasia.
 

Author(s): Anca Dimitriu, Cristian Gheorghe

Journal: Chirurgia (Bucur). ;113(1):61-69.

 

High resolution manometry (HRM) is currently the gold standard for the diagnosis of achalasia and other functional esophageal disorders. All patients accusing dysphagia should be endoscopically evaluated prior to manometric investigations in order to rule out pseudoachalasia. The ...

Last Updated: 31 Dec 1969

Go To URL
Per-oral endoscopic myotomy (POEM): a new endoscopic treatment for achalasia.
 

Author(s): Pablo Miranda García, Fernando Casals Seoane, Jean-Michel Gonzalez, Marc Barthet, Cecilio Santander Vaquero

Journal: Rev Esp Enferm Dig. 2017 Oct;109(10):719-726.

 

Per-oral endoscopic myotomy (POEM) is a new minimally invasive technique to treat achalasia.

Last Updated: 31 Dec 1969

Go To URL
Primary Esophageal Motility Disorders: Beyond Achalasia.
 

Author(s): Francisco Schlottmann, Marco G Patti

Journal:

 

The best-defined primary esophageal motor disorder is achalasia. However, symptoms such as dysphagia, regurgitation and chest pain can be caused by other esophageal motility disorders. The Chicago classification introduced new manometric parameters and better defined esophageal motility ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Sensorimotor Dysfunction in Achalasia
 

Status: Not yet recruiting

Condition Summary: Achalasia

 

Last Updated: 11 Feb 2018

Go to URL
Randomised Trial Between LHM Alone Vs LHM With Anterior Fundoplication In Achalasia Cardia
 

Status: Recruiting

Condition Summary: Achalasia Cardia

 

Last Updated: 20 Feb 2018

Go to URL
Endoscopic Myotomy of the Lower Esophageal Sphincter for Achalasia
 

Status: Recruiting

Condition Summary: Achalasia

 

Last Updated: 28 Dec 2017

Go to URL