Acid reflux

Common Name(s)

Acid reflux, Gastroesophageal reflux

Acid reflux, also known as gastroesophageal reflux, is a common condition in which stomach acid flows up into the esophagus. This causes a burning, painful feeling in the chest more commonly known as heartburn or acid indigestion.

The stomach makes a strong acid to help break down food and to protect the body from bacteria. The stomach is not harmed by the acid because it has a special lining. The esophagus is the tube that takes food from the mouth to the stomach. It does not have the special lining, so it will be irritated by the stomach acid. Normally a special ring of muscle, the lower esophageal sphincter (LES), keeps the stomach’s contents from flowing up into the esophagus. Acid reflux happens most often when the LES is not working correctly.

Symptoms of acid reflux include heartburn, bitter or sour taste in the mouth, difficulty swallowing, a chronic dry cough, wheezing and hoarseness. Heartburn usually occurs after a meal, lasts several hours and worsens while lying down. Although it is not clear what causes the LES to weaken, certain factors seem to increase the risk of developing acid reflux including obesity, pregnancy, having a hiatal hernia, smoking, drinking alcohol and caffeine, and taking certain medications. Certain types of foods may also trigger an heartburn episode.

Most people manage occasional heartburn with over-the-counter antacids and medications which decrease stomach acid production. Lifestyle changes such as losing weight, changing diet and drinking habits, exercising and stopping smoking may also help. If you are experiencing acid reflux more than 2 times per week, talk to your doctor because you may have a more long-term condition called gastroesophageal reflux disease (GERD). If you or a loved one is experiencing the symptoms of acid reflux, talk to your doctor about which treatment options are right for you. Support groups are also a good source of information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acid reflux" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acid reflux" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acid reflux" returned 169 free, full-text research articles on human participants. First 3 results:

Decline in perception of acid regurgitation symptoms from gastroesophageal reflux disease in diabetes mellitus patients.
 

Author(s): Kosuke Sakitani, Nobumi Suzuki, Sozaburo Ihara, Yoshihiro Hirata, Shoji Kawazu, Yasuhiko Iwamoto, Kazuhiko Koike

Journal:

 

To determine if a discrepancy exists between subjective symptoms and the grade of endoscopic gastroesophageal reflux disease (GERD) in diabetes mellitus (DM) patients.

Last Updated: 31 Dec 1969

Go To URL
The Characteristics of Postprandial Proximal Gastric Acid Pocket in Gastroesophageal Reflux Disease.
 

Author(s): Jing Wu, Dong Liu, Cheng Feng, Yumei Luo, Yuanyuan Nian, Xueqin Wang, Jun Zhang

Journal:

 

BACKGROUND Postprandial proximal gastric acid pocket (PPGAP) plays important roles in gastroesophageal reflux disease (GERD). In this study, we analyzed the characteristics of PPGAP in GERD. MATERIAL AND METHODS There were 17 normal participants and 20 GERD patients who completed ...

Last Updated: 31 Dec 1969

Go To URL
Gastroesophageal flap valve reflected EGJ morphology and correlated to acid reflux.
 

Author(s): Chenxi Xie, Yuwen Li, Ning Zhang, Lishou Xiong, Minhu Chen, Yinglian Xiao

Journal:

 

The anatomy of esophagogastric junction (EGJ) serves as the anti-reflux barrier. The gastroesophageal flap valve (GEFV) is a component of EGJ. The aim of the current study was to assess its correlation with the esophageal acid exposure and the impact on anti-reflux barrier function ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acid reflux" returned 23 free, full-text review articles on human participants. First 3 results:

What is the long term acid inhibitor treatment in gastroesophageal reflux disease? What are the potential problems related to long term acid inhibitor treatment in gastroesophageal reflux disease? How should these cases be followed?
 

Author(s): İbrahim Hatemi, Sinem Nihal Esatoğlu

Journal: Turk J Gastroenterol. 2017 12;28(Suppl 1):S57-S60.

 

The meta-analyses of observational studies (OBS) showed the risk of any fracture and hip fracture slightly increased with proton pump inhibitor (PPI) treatment depending on the dose and regardless of time. This was not observed with histamine-2 receptor antagonists (H2RA). The risk ...

Last Updated: 31 Dec 1969

Go To URL
Efficacy of acid suppression therapy in gastroesophageal reflux disease-related chronic laryngitis.
 

Author(s): Yue Yang, Haitao Wu, Jian Zhou

Journal: Medicine (Baltimore). 2016 Oct;95(40):e4868.

 

This research aims to assess the response to acid suppression therapy in gastroesophageal reflux disease (GERD)-related chronic laryngitis (CL).

Last Updated: 31 Dec 1969

Go To URL
Dimercaptosuccinic acid scan challenges in childhood urinary tract infection, vesicoureteral reflux and renal scarring investigation and management.
 

Author(s): Stylianos Roupakias, Xenophon Sinopidis, George Tsikopoulos, Ioannis Spyridakis, Ageliki Karatza, Anastasia Varvarigou

Journal: Minerva Urol Nefrol. 2017 Apr;69(2):144-152.

 

Vesicoureteral reflux (VUR) is a precipitating factor in acute pyelonephritis (APN), and a risk factor for renal scar formation, even if VUR and APN occur independently. There is no scientific evidence on a specific diagnostic evaluation of children after a febrile urinary tract infection ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study
 

Status: Recruiting

Condition Summary: Non-erosive Reflux Disease

 

Last Updated: 16 Jan 2018

Go to URL
Omega Loop Gastric Bypass With And Without Anti-Reflux Sutures
 

Status: Not yet recruiting

Condition Summary: Bile Reflux

 

Last Updated: 23 Mar 2018

Go to URL
Radiofrequency Energy Delivery for Gastroesophageal Reflux Disease
 

Status: Recruiting

Condition Summary: Gastroesophageal Reflux Disease

 

Last Updated: 18 Jul 2017

Go to URL