Rosacea

Common Name(s)

Rosacea, Acne rosacea

Rosacea is a facial skin condition characterized by redness, small bumps, and pimples. People with rosacea have flare-ups of symptoms and most do not have symptoms at all times. Over time however, the redness becomes ruddier and blood vessels will become visible. Although the condition most commonly affects the cheeks, nose, chin, and forehead, it may sometimes appear on the neck, chest, scalp, or ears. The cause of rosacea is not known, but it is believed to be a combination of genetics (changes or mutations in our genes) and environmental causes. There are four subtypes of rosacea (subtypes 1-4); these commonly affect different areas of the face and can cause slightly different symptoms.

The common symptoms of rosacea are flushing, persistent redness (often resembling sunburn), bumps and pimples which may burn or sting, and visible blood vessels. Symptoms may also include dry skin, an enlarged nose (rhinophyma), and eye problems such as dryness, irritation, or swelling. The condition mostly affects fair skinned women, although when affected, men tend to have more severe symptoms. Symptoms usually begin after age 30. Triggers of flare-ups may include any activity or substance which increases blood flow to the skin. These triggers may include hot or spicy foods, alcohol, temperature extremes, stress, anger, embarrassment, hard exercise, saunas, and certain prescription drugs.

Rosacea is normally diagnosed by examining the affected areas of the face. Often your primary doctor will refer you to a dermatologist or doctor who specializes in treating skin disorders. There is no cure for rosacea but there are treatment options including medications, laser treatments, and surgery if the nose is severely affected. Research is ongoing, so talk to your dermatologist about the most current treatment options. Support groups are also a good source of information and can help connect you with others affected by rosacea.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rosacea" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rosacea" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rosacea" returned 133 free, full-text research articles on human participants. First 3 results:

Bilateral Morganella Morganii keratitis in a patient with facial topical corticosteroid-induced rosacea-like dermatitis: a case report.
 

Author(s): Bei Zhang, Fei Pan, Kejian Zhu

Journal:

 

Bilateral keratitis rarely occurs in individuals without predisposing factors. Here we describe the clinical course of a patient who developed a bilateral keratitis caused by Morganella. morganii which might be associated with long term using of topical corticosteroids-containing ...

Last Updated: 29 Jun 2017

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TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis.
 

Author(s): Yong Chen, Carlene D Moore, Jennifer Y Zhang, Russell P Hall, Amanda S MacLeod, Wolfgang Liedtke

Journal: J. Invest. Dermatol.. 2017 Apr;137(4):801-804.

 

Mascarenhas et al. report that TRPV4 expression is upregulated in mast cells in response to the proteolytic cathelicidin fragment LL37 in a murine rosacea model and that TRPV4 loss of function attenuates mast cell degranulation. These findings render TRPV4 a translational-medical ...

Last Updated: 25 Mar 2017

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Rosacea fulminans: unusual clinical presentation of rosacea.
 

Author(s): Jessica Castiel Coutinho, Danielle Cristine Westphal, Laís Cruz Lobato, Antônio Pedro Mendes Schettini, Mônica Santos

Journal: An Bras Dermatol. ;91(5 suppl 1):151-153.

 

Rosacea fulminans or pyoderma faciale is a rare cutaneous disorder that usually affects women usually between the ages of 15-46. The disease is characterized by sudden onset of papules, pustules, cysts, and painful coalescing nodules with red-cyanotic centrofacial erythema. Although ...

Last Updated: 16 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rosacea" returned 26 free, full-text review articles on human participants. First 3 results:

Rosacea: Molecular Mechanisms and Management of a Chronic Cutaneous Inflammatory Condition.
 

Author(s): Yu Ri Woo, Ji Hong Lim, Dae Ho Cho, Hyun Jeong Park

Journal:

 

Rosacea is a chronic cutaneous inflammatory disease that affects the facial skin. Clinically, rosacea can be categorized into papulopustular, erythematotelangiectatic, ocular, and phymatous rosacea. However, the phenotypic presentations of rosacea are more heterogeneous. Although ...

Last Updated: 21 Sep 2016

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Topical Ivermectin 10 mg/g and Oral Doxycycline 40 mg Modified-Release: Current Evidence on the Complementary Use of Anti-Inflammatory Rosacea Treatments.
 

Author(s): Martin Steinhoff, Marc Vocanson, Johannes J Voegel, Feriel Hacini-Rachinel, Gregor Schäfer

Journal: Adv Ther. 2016 Sep;33(9):1481-501.

 

Rosacea is a common, chronic inflammatory skin disease that can present with a variety of signs and symptoms. The potentially simultaneous occurrence of different signs and symptoms is due to different underlying inflammatory pathways, emphasizing the need for complementary treatment ...

Last Updated: 13 Sep 2016

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Low-Dose Isotretinoin: An Option for Difficult-to-Treat Papulopustular Rosacea.
 

Author(s): Esther J van Zuuren, Zbys Fedorowicz

Journal: J. Invest. Dermatol.. 2016 Jun;136(6):1081-3.

 

Rosacea is a chronic disease with a profound impact on quality of life. Although there are a range of treatments for its many manifestations, some cases are difficult to treat. Sbidian et al. show in this double-blind, randomized, placebo-controlled trial that low-dose isotretinoin ...

Last Updated: 23 May 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Intense Pulsed Light as an Adjunctive to Bromonidine for the Treatment of Rosacea
 

Status: Not yet recruiting

Condition Summary: Rosacea

 

Last Updated: 23 Feb 2017

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Genetic Basis of Rosacea
 

Status: Recruiting

Condition Summary: Rosacea

 

Last Updated: 24 Apr 2017

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Photodynamic Therapy for Papulopustular Rosacea
 

Status: Recruiting

Condition Summary: Rosacea; Papulopustular Rosacea

 

Last Updated: 22 Feb 2017

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