Acute Disseminated Encephalomyelitis

Common Name(s)

Acute Disseminated Encephalomyelitis

Acute disseminated encephalomyelitis (ADEM) is a neurological condition characterized by a brief but intense attack of inflammation in the brain and spinal cord that damages myelin Ð the protective covering of nerve fibers.  It often follows viral infection, or less often, vaccination for measles, mumps, or rubella. Treatment for ADEM is targeted at suppressing inflammation in the brain using anti-inflammatory drugs. Plasmapheresis or intravenous immunoglobulin therapy may also be used.  Additional treatment is symptomatic and supportive.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acute Disseminated Encephalomyelitis" for support, advocacy or research.

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

Last Updated: 22 Apr 2015

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The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acute Disseminated Encephalomyelitis" for support, advocacy or research.

Logo
Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

http://www.pediatricbrainfoundation.org

Last Updated: 22 Apr 2015

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The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Research and Educational Symposia

Recordings of all our national and international symposia are made available for our community to learn more about rare neuro-immune diseases

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acute Disseminated Encephalomyelitis" returned 128 free, full-text research articles on human participants. First 3 results:

Two Cases of Acute Disseminated Encephalomyelitis Following Vaccination Against Human Papilloma Virus.
 

Author(s): Kenji Sekiguchi, Naoko Yasui, Hisatomo Kowa, Fumio Kanda, Tatsushi Toda

Journal: Intern. Med.. ;55(21):3181-3184.

 

We herein present two cases of acute disseminated encephalomyelitis (ADEM) following vaccination against human papilloma virus (HPV). Case 1 experienced diplopia and developed an unstable gait 14 days after a second vaccination of Cervarix. Brain magnetic resonance imaging (MRI) showed ...

Last Updated: 2 Nov 2016

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Bilateral abducens nerve palsy in an infant case of fulminant acute disseminated encephalomyelitis: a case report.
 

Author(s): Zhiliang Yang, Guilian Sun

Journal:

 

Sixth (abducens) nerve palsy (ANP) is far less frequent in children and has not been reported as a sign of acute disseminated encephalomyelitis (ADEM). We present an infant case of ADEM with bilateral abducens nerve palsy (BANP).

Last Updated: 26 Oct 2016

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An Adult Case of Anti-Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Multiphasic Acute Disseminated Encephalomyelitis at 33-year Intervals.
 

Author(s): Soichiro Numa, Takashi Kasai, Takayuki Kondo, Yukie Kushimura, Ayaka Kimura, Hisashi Takahashi, Kanako Morita, Akihiro Tanaka, Yu-Ichi Noto, Tomoyuki Ohara, Masanori Nakagawa, Toshiki Mizuno

Journal: Intern. Med.. 2016 ;55(6):699-702.

 

Acute disseminated encephalomyelitis (ADEM) followed by optic neuritis (ON) has been reported as a distinct phenotype associated with anti-myelin oligodendrocyte protein (MOG) antibody. We herein report the case of a 37-year-old woman who was diagnosed with ADEM at 4 years old of ...

Last Updated: 17 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acute Disseminated Encephalomyelitis" returned 8 free, full-text review articles on human participants. First 3 results:

Therapeutic Approach to the Management of Pediatric Demyelinating Disease: Multiple Sclerosis and Acute Disseminated Encephalomyelitis.
 

Author(s): J Nicholas Brenton, Brenda L Banwell

Journal: Neurotherapeutics. 2016 Jan;13(1):84-95.

 

Acquired pediatric demyelinating diseases manifest acutely with optic neuritis, transverse myelitis, acute disseminated encephalomyelitis, or with various other acute deficits in focal or polyfocal areas of the central nervous system. Patients may experience a monophasic illness (as ...

Last Updated: 16 May 2016

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Acute disseminated encephalomyelitis as the first presentation of CNS tuberculosis: report of a case with brief review.
 

Author(s): Ibrahim Masoodi, Omar Farooq, Iqbal Ahmad, Mohammad Yaseen Bhat, Nazir Ahmad, Hamid-ullah Wani, Javeed Ahmad Dar

Journal:

 

Acute disseminated encephalomyelitis (ADEM) also known as post infectious encephalomyelitis is a demyelinating disease of the central nervous system (CNS) that typically presents as a monophasic disorder associated with multifocal neurological symptoms and disability. It may follow ...

Last Updated: 8 Dec 2010

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Small cell lung carcinoma presenting with acute disseminated encephalomyelitis.
 

Author(s): R Summerfield, A Al-Saleh, S E Robbins

Journal: Br J Radiol. 2010 Mar;83(987):e54-7.

 

Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease characterised by subcortical high-signal white matter lesions on T2 weighted MRI. It most commonly occurs in children following an acute viral illness. We present a case study in which ADEM was the presenting condition ...

Last Updated: 3 Mar 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.