Adenoid cystic carcinoma

Common Name(s)

Adenoid cystic carcinoma

Adenoid cystic carcinoma is a rare type of cancer that usually develops in the salivary glands, which are the areas of the body where saliva is produced. Although less common, adenoid cystic carcinoma can also grow inside the breasts, eyes, lungs, brain, throat, and paranasal sinuses. Cancers form when a change (mutation) in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis.

Adenoid cystic carcinoma most commonly occurs in adults between the ages of 40 and 60, although it can appear in all age groups. The most common symptom of adenoid cystic carcinoma is painless swelling on the face, neck, or mouth area. This cancer may also cause facial pain and nerve paralysis, which results in difficulty displaying facial expressions. Depending on the size of the cancer, affected individuals may also experience difficulty with vision or breathing. Diagnosis is usually made with a combination of a physical exam, imaging studies, blood tests, and other laboratory studies. Diagnosis may require a doctor to take a biopsy, or sample, of the tissue to look at under a microscope in order to determine if the cells are growing in an abnormal way.

Treatment for adenoid cystic carcinoma depends on many factors such as how large the cancer is and if it has spread to other areas of the body. If you or a family member has been diagnosed with adenoid cystic carcinoma, talk to your doctor about the most current treatment options. Support groups are also available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adenoid cystic carcinoma" for support, advocacy or research.

Adenoid Cystic Carcinoma Research Foundation

The Adenoid Cystic Carcinoma Research Foundation (ACCRF) supports research into adenoid cystic carcinoma that will accelerate the development of improved therapies and a cure for the disease.

Last Updated: 5 May 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adenoid cystic carcinoma" for support, advocacy or research.

Adenoid Cystic Carcinoma Research Foundation

The Adenoid Cystic Carcinoma Research Foundation (ACCRF) supports research into adenoid cystic carcinoma that will accelerate the development of improved therapies and a cure for the disease.

http://www.accrf.org

Last Updated: 5 May 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Adenoid cystic carcinoma" returned 393 free, full-text research articles on human participants. First 3 results:

Adenoid cystic carcinoma of the hard palate presenting as ipsilateral sixth nerve palsy.
 

Author(s): Akshay Gopinathan Nair, Indumati Gopinathan, Rima Singh, Rima S Pathak

Journal: Indian J Ophthalmol. 2018 08;66(8):1218-1220.

 

Adenoid cystic carcinoma (ACC) is an uncommon malignant neoplasm composed of basaloid epithelial and myoepithelial cells. The palate is the most commonly involved intraoral site for ACC. Here, we document the case of an advanced ACC arising from the hard palate that presented with ...

Last Updated: 31 Dec 1969

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Ataxia-Telangiectasia-Mutated Protein Expression as a Prognostic Marker in Adenoid Cystic Carcinoma of the Salivary Glands.
 

Author(s): Shadavlonjid Bazarsad, Jue Young Kim, Xianglan Zhang, Ki Yeol Kim, Doo Young Lee, Mi Heon Ryu, Jin Kim

Journal: Yonsei Med. J.. 2018 Aug;59(6):717-726.

 

Adenoid cystic carcinoma (ACC) is a high-grade malignant tumor of the salivary glands, clinically characterized by multiple recurrences and late distant metastasis. Biological markers for assessing the prognosis of ACC have remained elusive. The purpose of this study was to investigate ...

Last Updated: 31 Dec 1969

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[Bronchial adenoid cystic carcinoma masquerading as bronchial asthma: a case report].
 

Author(s): M Lu, M Wang, X Zhu, Y H Chen, W Z Yao

Journal: Beijing Da Xue Xue Bao. 2018 Apr;50(2):378-380.

 

Here we reported a case of bronchial adenoid cystic carcinoma from Peking University Third Hospital. A 40-year-old female presented with dry cough for 1 year and nocturnal paroxysmal attacks of wheezing for 4 months. She was a non-smoker, and did not have past histories of asthma ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Adenoid cystic carcinoma" returned 48 free, full-text review articles on human participants. First 3 results:

Lung metastasis in primary cutaneous adenoid cystic carcinoma - Clinicopathological evaluation of a rare case with review of literature.
 

Author(s): Gunjesh Kumar Singh, Pragya Singh, Jaspreet Kaur, Rakesh Kumar

Journal: J Egypt Natl Canc Inst. 2017 Sep;29(3):163-165.

 

Primary cutaneous adenoid cystic carcinoma (ACC) is an extremely rare and indolent cutaneous malignancy with very infrequent distant metastasis. We present a case of primary cutaneous ACC with bilateral lung metastases in a 57-year-old male along with literature review. To the best ...

Last Updated: 31 Dec 1969

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Prognostic significance of p53 immunohistochemical expression in adenoid cystic carcinoma of the salivary glands: a meta-analysis.
 

Author(s): Qinglin Li, Ping Huang, Chuanming Zheng, Jiafeng Wang, Minghua Ge

Journal: Oncotarget. 2017 Apr;8(17):29458-29473.

 

Adenoid cystic carcinoma of salivary glands is a rare adenocarcinoma and has been placed in "high-risk" category as poor long-term prognosis. The purpose of this study was to investigate p53 protein expression in adenoid cystic carcinoma of salivary glands and its correlation with ...

Last Updated: 31 Dec 1969

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Cervical lymph node metastasis in adenoid cystic carcinoma of the sinonasal tract, nasopharynx, lacrimal glands and external auditory canal: a collective international review.
 

Author(s):

Journal: J Laryngol Otol. 2016 Dec;130(12):1093-1097.

 

To review reports of adenoid cystic carcinomas arising in the head and neck area outside of the major salivary glands, in order to enhance the care of patients with these unusual neoplasms.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study Of AL101 In Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations
 

Status: Not yet recruiting

Condition Summary: Adenoid Cystic Carcinoma

 

Last Updated: 25 Sep 2018

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Trail Evaluating Particle Therapy With or Without Apatinib for H&N Adenoid Cystic Carcinoma
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinoma

 

Last Updated: 26 Sep 2018

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Chidamide Combined With Cisplatin in Head and Neck Adenoid Cystic Carcinoma (HNACC)
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinomas; Chidamide; Cisplatin

 

Last Updated: 21 Aug 2018

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