Dercum's disease

Common Name(s)

Dercum's disease, Adiposis dolorosa

Adiposis dolorosa is a rare condition characterized by multiple, painful, fatty lipomas (benign, fatty tumors). The condition usually occurs in obese, post-menopausal women but a few cases have been reported in men. The lipomas generally occur anywhere except the face and neck and can cause severe pain. This condition is chronic and tends to be progressive. The exact cause of adiposis dolorosa is unknown. Most cases are sporadic but a few familial cases with autosomal dominant inheritance have been reported. Treatment is focused on the specific symptoms in the affected individual.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dercum's disease" for support, advocacy or research.

Fat Disorders Research Society

FDRS is dedicated to improving the quality of life for all people affected by adipose tissue disorders such as lipedema, lipoedema, Dercum's Disease, Madelung's Disease and Familial Multiple Lipomatosis, through research, education, advocacy and collaboration.

Last Updated: 9 Mar 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dercum's disease" for support, advocacy or research.

Fat Disorders Research Society

FDRS is dedicated to improving the quality of life for all people affected by adipose tissue disorders such as lipedema, lipoedema, Dercum's Disease, Madelung's Disease and Familial Multiple Lipomatosis, through research, education, advocacy and collaboration.

http://www.fatdisorders.org

Last Updated: 9 Mar 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dercum's disease" returned 5 free, full-text research articles on human participants. First 3 results:

Successful Treatment of Dercum's Disease by Transcutaneous Electrical Stimulation: A Case Report.
 

Author(s): Sabina Martinenghi, Amelia Caretto, Claudio Losio, Marina Scavini, Emanuele Bosi

Journal: Medicine (Baltimore). 2015 Jun;94(24):e950.

 

Dercum's disease is a rare condition of painful subcutaneous growth of adipose tissue. Etiology is unknown and pain is difficult to control. We report the case of a 57-year-old man with generalized diffuse Dercum's disease, who improved after the treatment with transcutaneous frequency ...

Last Updated: 20 Jun 2015

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An abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in Dercum's disease.
 

Author(s): John C Rasmussen, Karen L Herbst, Melissa B Aldrich, Chinmay D Darne, I-Chih Tan, Banghe Zhu, Renie Guilliod, Caroline E Fife, Erik A Maus, Eva M Sevick-Muraca

Journal: Obesity (Silver Spring). 2014 Oct;22(10):2186-92.

 

Investigational, near-infrared fluorescence (NIRF) lymphatic imaging was used to assess lymphatic architecture and contractile function in participants diagnosed with Dercum's disease, a rare, poorly understood disorder characterized by painful lipomas in subcutaneous adipose tissues.

Last Updated: 29 Sep 2014

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Depression in Dercum's disease and in obesity: a case control study.
 

Author(s): Emma Hansson, Henry Svensson, Håkan Brorson

Journal:

 

Dercum's disease is characterised by pronounced pain in the adipose tissue and a number of associated symptoms. The condition is usually accompanied by generalised weight gain. Many of the associated symptoms could also be signs of depression. Depression in Dercum's disease has been ...

Last Updated: 10 Aug 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dercum's disease" returned 1 free, full-text review articles on human participants. First 3 results:

Review of Dercum's disease and proposal of diagnostic criteria, diagnostic methods, classification and management.
 

Author(s): Emma Hansson, Henry Svensson, Håkan Brorson

Journal:

 

DEFINITION AND CLINICAL PICTURE: We propose the minimal definition of Dercum's disease to be generalised overweight or obesity in combination with painful adipose tissue. The associated symptoms in Dercum's disease include fatty deposits, easy bruisability, sleep disturbances, impaired ...

Last Updated: 18 Sep 2012

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Insight Into Subcutaneous Adipose Tissue Disorders
 

Status: Recruiting

Condition Summary: Lipedema; Dercum's Disease; Familial Multiple Lipomatosis; Madelung's Disease

 

Last Updated: 15 Jul 2016

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