Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 1026 free, full-text research articles on human participants. First 3 results:

[Invasive pulmonary aspergillosis in children with hepatic transplant: a survivor].
 

Author(s): Verónica Botero, Víctor H García, Alejandro Delgado, Ana M Aristizabal, Catalina Gómez, Luis A Caicedo, Gabriel Jaime Echeverri

Journal: Rev Chil Pediatr. 2018 Apr;89(2):241-245.

 

Mycotic infections due to Aspergillus spp, are the main mycotic associated infections in liver transplant patients, with mortality rates up to 90% of the cases. Almost 50% of patients will de velop an infection during the first months after transplantation, of which 10% are associated ...

Last Updated: 31 Dec 1969

Go To URL
Concordance between Aspergillus-specific precipitating antibody and IgG in allergic bronchopulmonary aspergillosis.
 

Author(s): Kazuki Harada, Tsuyoshi Oguma, Akemi Saito, Yuma Fukutomi, Jun Tanaka, Katsuyoshi Tomomatsu, Masami Taniguchi, Koichiro Asano

Journal: Allergol Int. 2018 Sep;67S():S12-S17.

 

Several serological tests for specific precipitin or IgG are available to demonstrate type III hypersensitivity reactions to Aspergillus species and are essential for infectious fungal disease diagnosis. These assays are also important for allergic bronchopulmonary aspergillosis (ABPA) ...

Last Updated: 31 Dec 1969

Go To URL
[The tree that hides the forest: aspergillosis associated with bronchial carcinoma (about two cases)].
 

Author(s): Fatima Zahra Mrabet, Mouna Soualhi, Jihane Achrane, Yassir Sabri, Sanaa Hammi, Karima Marc, Jouda Benamor, Rachida Zahraoui, Jamal Eddine Bourkadi

Journal:

 

Endobronchial aspergilloma and intracavitary pulmonary aspergilloma may clinically and radiologically mimic a bronchial neoplasia, hence the importance of systematically searching for an association. A confirmed association completely changes the prognosis as well as the therapeutic ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 132 free, full-text review articles on human participants. First 3 results:

Spotlight on isavuconazole in the treatment of invasive aspergillosis and mucormycosis: design, development, and place in therapy.
 

Author(s): Jeffrey D Jenks, Helmut Jf Salzer, Juergen Prattes, Robert Krause, Dieter Buchheidt, Martin Hoenigl

Journal:

 

In recent decades, important advances have been made in the diagnosis and treatment of invasive aspergillosis (IA) and mucormycosis. One of these advances has been the introduction of isavuconazole, a second-generation broad spectrum triazole with a favorable pharmacokinetic and safety ...

Last Updated: 31 Dec 1969

Go To URL
[Focal brain lesion due to cerebral aspergillosis in a patient with AIDS. Case report and literature review].
 

Author(s): Emilse Vázquez, Fernando Messina, Gabriela Santiso, Humberto Metta, Ricardo Negroni

Journal: Rev Chilena Infectol. 2017 Oct;34(5):502-506.

 

Cerebral aspergillosis is a rare disease with high mortality rates in AIDS patients. It is important to take this into account in the differential diagnosis of a brain expansive lesion. A high level of suspicion is required to make an early diagnosis. We present a case of an HIV-infected ...

Last Updated: 31 Dec 1969

Go To URL
Invasive pulmonary aspergillosis and influenza co-infection in immunocompetent hosts: case reports and review of the literature.
 

Author(s): Melisa M Shah, Eric I Hsiao, Carl M Kirsch, Amit Gohil, Supriya Narasimhan, David A Stevens

Journal: Diagn. Microbiol. Infect. Dis.. 2018 Jun;91(2):147-152.

 

Invasive pulmonary aspergillosis (IPA) is classically considered an illness of severely immunocompromised patients with limited host defenses. However, IPA has been reported in immunocompetent but critically ill patients. This report describes two fatal cases of pathologically confirmed ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Pre-existing Invasive Aspergillosis on Allogeneic Stem Cell Transplantation
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 19 Jan 2017

Go to URL
Novel Biomarkers for Invasive Aspergillosis
 

Status: Recruiting

Condition Summary: Aspergillosis Invasive

 

Last Updated: 2 May 2018

Go to URL
Clinical Implications of Azole-Resistant Aspergillosis in Hematological Malignancy
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 29 Oct 2018

Go to URL