Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 991 free, full-text research articles on human participants. First 3 results:

[The tree that hides the forest: aspergillosis associated with bronchial carcinoma (about two cases)].
 

Author(s): Fatima Zahra Mrabet, Mouna Soualhi, Jihane Achrane, Yassir Sabri, Sanaa Hammi, Karima Marc, Jouda Benamor, Rachida Zahraoui, Jamal Eddine Bourkadi

Journal:

 

Endobronchial aspergilloma and intracavitary pulmonary aspergilloma may clinically and radiologically mimic a bronchial neoplasia, hence the importance of systematically searching for an association. A confirmed association completely changes the prognosis as well as the therapeutic ...

Last Updated: 31 Dec 1969

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Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages.
 

Author(s): Nicola L D Overton, Axel A Brakhage, Andreas Thywißen, David W Denning, Paul Bowyer

Journal:

 

Allergic bronchopulmonary aspergillosis (ABPA) in asthma is a severe, life-affecting disease that potentially affects over 4.8 million people globally. In the UK, ABPA is predominantly caused by the fungus Aspergillus fumigatus. Phagocytosis is important in clearance of this fungus, ...

Last Updated: 31 Dec 1969

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Evaluation of a commercial quantitative Aspergillus fumigatus-specific IgM assay for the diagnosis of invasive pulmonary aspergillosis.
 

Author(s): Yake Yao, Hua Zhou, Yihong Shen, Qing Yang, Jian Ye, Guohua Lu, Yiqi Fu, Haiyan Lou, Yunsong Yu, Jianying Zhou

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9436.

 

Invasive pulmonary aspergillosis (IPA) is a common fungal infection with high mortality rates in immunocompromised patients. Early diagnosis of IPA is still challenging because of its nonspecific clinical symptoms and radiological presentations.To evaluate the clinical value of a ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 129 free, full-text review articles on human participants. First 3 results:

[Focal brain lesion due to cerebral aspergillosis in a patient with AIDS. Case report and literature review].
 

Author(s): Emilse Vázquez, Fernando Messina, Gabriela Santiso, Humberto Metta, Ricardo Negroni

Journal: Rev Chilena Infectol. 2017 Oct;34(5):502-506.

 

Cerebral aspergillosis is a rare disease with high mortality rates in AIDS patients. It is important to take this into account in the differential diagnosis of a brain expansive lesion. A high level of suspicion is required to make an early diagnosis. We present a case of an HIV-infected ...

Last Updated: 31 Dec 1969

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Comments on practice guidelines for the diagnosis and management of aspergillosis made by the IDSA in 2016.
 

Author(s): E Alarcón-Manoja, C Cardozo-Espinola, P Puerta-Alcalde, C García-Vidal

Journal: Rev Esp Quimioter. 2017 Sep;30 Suppl 1():26-29.

 

We sought to review the most important updates in the treatment of aspergillosis after the publication of the clinical practice guidelines for the diagnosis and management of invasive aspergillosis (IA) by the Infectious Diseases Society of America. Our aim is to discuss some of the ...

Last Updated: 31 Dec 1969

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Novel cutting-edge metabolite-based diagnostic tools for aspergillosis.
 

Author(s): Masha G Savelieff, Lucia Pappalardo

Journal:

 

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Pre-existing Invasive Aspergillosis on Allogeneic Stem Cell Transplantation
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 19 Jan 2017

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Novel Biomarkers for Invasive Aspergillosis
 

Status: Recruiting

Condition Summary: Aspergillosis Invasive

 

Last Updated: 2 May 2018

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Clinical Implications of Azole-Resistant Aspergillosis in Hematological Malignancy
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 13 Jul 2017

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