Ataxia

Common Name(s)

Ataxia

Ataxia occurs as a result of damage to a part of the brain called the cerebellum which controls muscle movement. Other causes of ataxia include alcohol abuse, stroke, tumor, cerebral palsy or multiple sclerosis. Ataxia can be passed on through your genes without your parents ever showing symptoms of having the disease. Common symptoms of ataxia include slurred speech, difficulty walking, losing your balance and having trouble swallowing. As ataxia develops, it may become harder to walk, button up shirts, grasp small objects, swallow food/saliva or control your eye movements. Treatment for ataxia includes physical therapy, occupational therapy and/or speech therapy depending on what type of ataxia you have been diagnosed with.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ataxia" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

Last Updated: 5 May 2014

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National Ataxia Foundation

The National Ataxia Foundation is dedicated to improving the lives of persons affected by ataxia through support, education, and research.

Last Updated: 12 Dec 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ataxia" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

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Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

http://www.movementdisorders.org/MDS.htm

Last Updated: 5 May 2014

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National Ataxia Foundation

The National Ataxia Foundation is dedicated to improving the lives of persons affected by ataxia through support, education, and research.

http://www.ataxia.org

Last Updated: 12 Dec 2012

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ataxia" returned 1937 free, full-text research articles on human participants. First 3 results:

[Clinical features of 63 patients with ataxia].
 

Author(s): Paula Saffie Awad, Felipe Vial Undurraga, Pedro Chaná-Cuevas

Journal: Rev Med Chil. 2018 Jun;146(6):702-707.

 

Ataxia can be classified as genetic, sporadic or acquired.

Last Updated: 31 Dec 1969

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Ataxia-Telangiectasia-Mutated Protein Expression as a Prognostic Marker in Adenoid Cystic Carcinoma of the Salivary Glands.
 

Author(s): Shadavlonjid Bazarsad, Jue Young Kim, Xianglan Zhang, Ki Yeol Kim, Doo Young Lee, Mi Heon Ryu, Jin Kim

Journal: Yonsei Med. J.. 2018 Aug;59(6):717-726.

 

Adenoid cystic carcinoma (ACC) is a high-grade malignant tumor of the salivary glands, clinically characterized by multiple recurrences and late distant metastasis. Biological markers for assessing the prognosis of ACC have remained elusive. The purpose of this study was to investigate ...

Last Updated: 31 Dec 1969

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Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model.
 

Author(s): Lodewijk J A Toonen, Maurice Overzier, Melvin M Evers, Leticia G Leon, Sander A J van der Zeeuw, Hailiang Mei, Szymon M Kielbasa, Jelle J Goeman, Kristina M Hettne, Olafur Th Magnusson, Marion Poirel, Alexandre Seyer, Peter A C 't Hoen, Willeke M C van Roon-Mom

Journal:

 

Spinocerebellar ataxia type 3 (SCA3) is a progressive neurodegenerative disorder caused by expansion of the polyglutamine repeat in the ataxin-3 protein. Expression of mutant ataxin-3 is known to result in transcriptional dysregulation, which can contribute to the cellular toxicity ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ataxia" returned 157 free, full-text review articles on human participants. First 3 results:

Impact of Models in the Study and Treatment of Friedreich's Ataxia.
 

Author(s): Véronique Monnier, Jose Vicente Llorens, Juan Antonio Navarro

Journal:

 

has been for over a century the model of choice of several neurobiologists to decipher the formation and development of the nervous system as well as to mirror the pathophysiological conditions of many human neurodegenerative diseases. The rare disease Friedreich’s ataxia (FRDA) ...

Last Updated: 31 Dec 1969

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A systematic review of the gait characteristics associated with Cerebellar Ataxia.
 

Author(s): Ellen Buckley, Claudia Mazzà, Alisdair McNeill

Journal: Gait Posture. 2018 02;60():154-163.

 

Cerebellar Ataxias are a group of gait disorders resulting from dysfunction of the cerebellum, commonly characterised by slowly progressing incoordination that manifests as problems with balance and walking leading to considerable disability. There is increasing acceptance of gait ...

Last Updated: 31 Dec 1969

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Fragile X-associated tremor/ataxia syndrome.
 

Author(s): Gry Hoem, Jeanette Koht

Journal:

 

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a hereditary neurodegenerative disorder caused by a mutation on the X chromosome. The major signs and symptoms are tremor, ataxia and parkinsonism. Up to one in 2 000 persons over 50 years of age will develop the syndrome. There ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cerebellar Non-invasive Stimulation in Ataxias
 

Status: Recruiting

Condition Summary: Cerebellar Ataxia

 

Last Updated: 7 Jul 2017

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Biomarkers in Friedreich's Ataxia
 

Status: Recruiting

Condition Summary: Friedreich's Ataxia

 

Last Updated: 12 Jul 2018

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tDCS Associated With Locomotor Training on Functional Mobility of Cerebellar Ataxia
 

Status: Not yet recruiting

Condition Summary: Ataxia, Cerebellar

 

Last Updated: 10 Oct 2018

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