Atrial Septal Defect

Common Name(s)

Atrial Septal Defect

Atrial Septal Defect (ASD) is a relatively common heart defect that is present at birth. This defect occurs when an opening present between the upper chambers of an infant’s heart does not close after they are born, as it normally should. If this hole does not close, blood continues to flow between the two chambers, which may cause high pressures in the lungs as well as potential heart and lung complications later in life. Symptoms may include: difficulty breathing, respiratory infections, shortness of breath, and sensations of feeling your heartbeat. Symptoms may not present themselves if the hole is small enough, and if they do occur they usually occur later in life. Various heart tests can be used to see how large the hole it, and doctors can also diagnose this condition through physical exams. Surgery to close the hole might be necessary if it is too large or is not closing on its own. ASD can increase your risk of heart failure and infections, high blood pressure, and stoke.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Atrial Septal Defect" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Atrial Septal Defect" returned 619 free, full-text research articles on human participants. First 3 results:

Comparative study of the transcatheter and transthoracic device closure treatments for atrial septal defect: A Chinese single-institution experience.
 

Author(s): Qiang Chen, Hua Cao, Zhao-Yang Chen, Gui-Can Zhang, Liang-Wan Chen, Fan Xu, Jia-Jun He

Journal: Medicine (Baltimore). 2017 Mar;96(11):e6316.

 

The purpose of this study was to compare patient populations, safety, feasibility, complications, and total costs of the transcatheter and transthoracic device closure treatments for secundum atrial septal defect.From January 2014 to December 2014, we enrolled 155 patients with secundum ...

Last Updated: 15 Mar 2017

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Totally thoracoscopic surgery for atrial myxomas resection and atrial septal defect repair.
 

Author(s): L Deng, G-W Zhang, Z-H Liu, W-X Meng, H-Y Liu

Journal: Eur Rev Med Pharmacol Sci. 2017 Feb;21(3):569-575.

 

The purpose of this study is to compare the effectiveness and safety of thoracoscopic surgery and traditional median sternotomy.

Last Updated: 27 Feb 2017

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Comparison of Clinical Outcomes After Transcatheter vs. Minimally Invasive Cardiac Surgery Closure for Atrial Septal Defect.
 

Author(s): Masaki Kodaira, Akio Kawamura, Kazuma Okamoto, Hideaki Kanazawa, Yugo Minakata, Mitsushige Murata, Hideyuki Shimizu, Keiichi Fukuda

Journal: Circ. J.. 2017 Mar;81(4):543-551.

 

Percutaneous closure has replaced surgery for the majority of cases of secundum atrial septal defect (ASD). However, technological advances have made contemporary minimally invasive cardiac surgery (MICS) less invasive than conventional surgery. The aim of this study was to compare ...

Last Updated: 3 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Atrial Septal Defect" returned 16 free, full-text review articles on human participants. First 3 results:

Atrial septal defect closure with left ventricular dysfunction.
 

Author(s): Victor-Xavier Tadros, Anita W Asgar

Journal: EuroIntervention. 2016 May;12 Suppl X():X13-X17.

 

Atrial septal defects are one of the most common congenital heart diseases in adults that may result in significant left to right shunt. Secundum atrial septal defects can remain unrecognised until adult age and cause haemodynamic changes with or without symptoms. Transcatheter ASD ...

Last Updated: 13 May 2016

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Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2-5 Mutation and a Review of the Literature.
 

Author(s): Sabrina Gade Ellesøe, Morten Munk Johansen, Jesper Vandborg Bjerre, Vibeke Elisabeth Hjortdal, Søren Brunak, Lars Allan Larsen

Journal: Congenit Heart Dis. 2016 May;11(3):283-90.

 

Atrial septal defect (ASD) is the second most common congenital heart defect (CHD) and is observed in families as an autosomal dominant trait as well as in nonfamilial CHD. Mutations in the NKX2-5 gene, located on chromosome 5, are associated with ASD, often combined with conduction ...

Last Updated: 9 Jun 2016

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Giant, pedunculated right atrial thrombus formation after surgical atrial septal defect repair.
 

Author(s): Sayqa Arif, Dincer Aktuerk, David J Barron

Journal: J. Thorac. Cardiovasc. Surg.. 2015 Mar;149(3):e46-8.

 

Last Updated: 1 Apr 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Dec 2015

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Last Updated: 5 Apr 2016

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Safety and Efficacy Study of Transcatheter Closure of Ostium Secundum ASDs
 

Status: Recruiting

Condition Summary: Atrial Septal Defect

 

Last Updated: 5 Apr 2017

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