Atrial Septal Defect

Common Name(s)

Atrial Septal Defect

Atrial Septal Defect (ASD) is a relatively common heart defect that is present at birth. This defect occurs when an opening present between the upper chambers of an infant’s heart does not close after they are born, as it normally should. If this hole does not close, blood continues to flow between the two chambers, which may cause high pressures in the lungs as well as potential heart and lung complications later in life. Symptoms may include: difficulty breathing, respiratory infections, shortness of breath, and sensations of feeling your heartbeat. Symptoms may not present themselves if the hole is small enough, and if they do occur they usually occur later in life. Various heart tests can be used to see how large the hole it, and doctors can also diagnose this condition through physical exams. Surgery to close the hole might be necessary if it is too large or is not closing on its own. ASD can increase your risk of heart failure and infections, high blood pressure, and stoke.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Atrial Septal Defect" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Atrial Septal Defect" returned 627 free, full-text research articles on human participants. First 3 results:

Percutaneous closure of residual shunting in a patient with a fenestrated atrial septal defect occluder: A case report.
 

Author(s): Wang Man, Ma Xinxin, Zhang Yueli, Li Feng

Journal: Medicine (Baltimore). 2018 Aug;97(31):e11612.

 

Fenestrated atrial septal defect (ASD) occlusion has been performed in patients complicated with severe pulmonary hypertension (PH). Nevertheless, the persistent interatrial residual shunting in the fenestration might increase the risk of paradoxical embolism. Percutaneous closure ...

Last Updated: 31 Dec 1969

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Rapid Left Ventricular Recovery After Correction of a Secundum Atrial Septal Defect: Understanding the Hemodynamics.
 

Author(s): Akanksha N Thakkar, Mahwash Kassi, C Huie Lin

Journal: Methodist Debakey Cardiovasc J. ;13(3):160-164.

 

Closure of an atrial septal defect (ASD) may lead to a change in the function of both ventricles. Although right ventricular function typically improves, the left ventricle (LV) may behave in different ways. This has been a matter of much debate, with some authors reporting a decline ...

Last Updated: 31 Dec 1969

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Atrial Septal Defect as Unexpected Cause of Pulmonary Artery Hypertension.
 

Author(s): Rushi V Parikh, Jack Boyd, David P Lee, Ronald Witteles

Journal:

 

Methamphetamine abuse is an increasingly prevalent cause of pulmonary artery hypertension in the United States. Conversely, an atrial septal defect rarely presents late as pulmonary artery hypertension. We present the case of a 44-year-old methamphetamine abuser who had a 3-month ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Atrial Septal Defect" returned 15 free, full-text review articles on human participants. First 3 results:

Spontaneous Closure of a Secundum Atrial Septal Defect.
 

Author(s): Stephen Y Wang, Terrence D Welch, Aryé Elfenbein, Aaron V Kaplan

Journal: Methodist Debakey Cardiovasc J. ;14(1):60-62.

 

Spontaneous closure of an atrial septal defect (ASD) is well described in pediatric cardiology but may be less familiar to adult internists and cardiologists. We report a moderately sized 6-mm ASD that closed spontaneously without intervention. A literature review found that a smaller ...

Last Updated: 31 Dec 1969

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Atrial septal defect closure with left ventricular dysfunction.
 

Author(s): Victor-Xavier Tadros, Anita W Asgar

Journal: EuroIntervention. 2016 May;12 Suppl X():X13-X17.

 

Atrial septal defects are one of the most common congenital heart diseases in adults that may result in significant left to right shunt. Secundum atrial septal defects can remain unrecognised until adult age and cause haemodynamic changes with or without symptoms. Transcatheter ASD ...

Last Updated: 31 Dec 1969

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Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2-5 Mutation and a Review of the Literature.
 

Author(s): Sabrina Gade Ellesøe, Morten Munk Johansen, Jesper Vandborg Bjerre, Vibeke Elisabeth Hjortdal, Søren Brunak, Lars Allan Larsen

Journal: Congenit Heart Dis. 2016 May;11(3):283-90.

 

Atrial septal defect (ASD) is the second most common congenital heart defect (CHD) and is observed in families as an autosomal dominant trait as well as in nonfamilial CHD. Mutations in the NKX2-5 gene, located on chromosome 5, are associated with ASD, often combined with conduction ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Atrial Septal Defect - Exercise Capacity and Pulmonary Hypertension
 

Status: Recruiting

Condition Summary: Atrial Septal Defect; Pulmonary Hypertension

 

Last Updated: 21 Jun 2018

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Safety and Efficacy Study of Transcatheter Closure of Ostium Secundum ASDs
 

Status: Recruiting

Condition Summary: Atrial Septal Defect

 

Last Updated: 20 Sep 2018

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Efficacy of Three Dimensional Transesophageal Echocardiography for Percutaneous Device Closure in Atrial Septal Defect
 

Status: Recruiting

Condition Summary: Atrial Septal Defect; Successful Device Closure

 

Last Updated: 9 Jan 2018

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