Autoimmune Enteropathy

Common Name(s)

Autoimmune Enteropathy

Autoimmune Enteropathy is a condition in which the body’s immune system attacks itself and irritates the lining of the intestine, causing severe diarrhea. This condition can cause a severe lack of fluids, which may require an IV, and can affect the patient’s ability to absorb food and vitamins. Symptoms may include: diarrhea, poor weight gain and weight loss, decreased urine output, frequent infections, blood in the stool, and skin rashes. There are several different types of autoimmune enteropathy, some of which may be linked with other diseases like diabetes and kidney disease. This condition occurs most in infants and young children, although it can affect adults as well. Physicians can diagnose this condition by using blood tests or endoscopies (tests that look at the stomach and small intestines), or doctors can sometimes diagnose this condition by looking at the family’s medical history. Treatment typically involves medications to suppress the immune system (so that it will stop attacking itself), special diets, and very rarely surgery.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Enteropathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Enteropathy" returned 21 free, full-text research articles on human participants. First 3 results:

Adult autoimmune enteropathy presenting initially with acquired Acrodermatitis Enteropathica: a case report.
 

Author(s): Erina Lie, Sarah Sung, Steven Hoseong Yang

Journal:

 

Acrodermatitis enteropathica (AE) is a rare dermatitis secondary to zinc deficiency most commonly seen as an inherited disease in infants. In the last decade, increased number of reports have been published on the acquired form that presents in adulthood. Unlike its inherited counterpart, ...

Last Updated: 31 Dec 1969

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Wireless capsule endoscopy as a tool in diagnosing autoimmune enteropathy.
 

Author(s): Eva-Marie Gram-Kampmann, Søren T Lillevang, Sönke Detlefsen, Stig Borbjerg Laursen

Journal:

 

Autoimmune enteropathy (AE) is an immune mediated illness of the intestinal mucosa. The cause is unknown, and the diagnosis is based on typical characteristics displayed. There is no gold standard for treatment. We present two adult cases of AE and demonstrate the challenges in establishing ...

Last Updated: 31 Dec 1969

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Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy.
 

Author(s): Sophie Scialom, Georgia Malamut, Bertrand Meresse, Nicolas Guegan, Nicole Brousse, Virginie Verkarre, Coralie Derrieux, Elizabeth Macintyre, Philippe Seksik, Guillaume Savoye, Guillaume Cadiot, Lucine Vuitton, Lysiane Marthey, Franck Carbonnel, Nadine Cerf-Bensussan, Christophe Cellier

Journal:

 

Anti-hypertensive treatment with the angiotensin II receptor antagonist olmesartan is a rare cause of severe Sprue-like enteropathy. To substantiate the hypothesis that olmesartan interferes with gut immune homeostasis, clinical, histopathological and immune features were compared ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Enteropathy" returned 3 free, full-text review articles on human participants. First 3 results:

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders: an evolving web of heritable autoimmune diseases.
 

Author(s): James W Verbsky, Talal A Chatila

Journal: Curr. Opin. Pediatr.. 2013 Dec;25(6):708-14.

 

To summarize recent progress in our understanding of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders.

Last Updated: 31 Dec 1969

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Autoimmune enteropathy: a review and update of clinical management.
 

Author(s): Nicole M Gentile, Joseph A Murray, Darrell S Pardi

Journal: Curr Gastroenterol Rep. 2012 Oct;14(5):380-5.

 

Autoimmune enteropathy (AIE) is a rare condition characterized by intractable diarrhea, histologic changes on small intestinal biopsy, and failed response to dietary manipulation that also may present with extraintestinal manifestations. In many patients, immunosuppressive therapies ...

Last Updated: 31 Dec 1969

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Autoimmune enteropathy with a CD8+ CD7- T-cell small bowel intraepithelial lymphocytosis: case report and literature review.
 

Author(s): Shrinivas Bishu, Violeta Arsenescu, Eun Y Lee, H David Vargas, Willem J S de Villiers, Razvan Arsenescu

Journal:

 

Adult onset autoimmune enteropathy (AIE) is a rare condition characterized by diarrhea refractory to dietary therapy diagnosed in patients with evidence of autoimmune conditions. Auto-antibodies to gut epithelial cells and other tissues are commonly demonstrated. Despite increasing ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Antibody Treatment for Advanced Celiac Disease
 

Status: Recruiting

Condition Summary: Celiac Disease; Celiac Sprue; Gluten Enteropathy; Gluten-Sensitive Enteropathy

 

Last Updated: 4 Jul 2018

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Chronic Inflammatory Disease, Lifestyle and Risk of Disease
 

Status: Not yet recruiting

Condition Summary: Autoimmune Diseases; Inflammatory Bowel Diseases; Crohn Disease (CD); Ulcerative Colitis (UC); Arthritis, Rheumatoid (RA); Spondylarthropathies; Arthritis, Psoriatic (PsA); Psoriasis (PsO); Multiple Sclerosis (MS)

 

Last Updated: 6 Apr 2018

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The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing
 

Status: Recruiting

Condition Summary: Patients Undergoing Routine Health Care; Heart Diseases; Inflammatory Bowel Diseases; Autoimmune Disease; Inflammatory Disease; Blood Coagulation Disorders; Hepatitis C; Non-Metastatic Neoplasm

 

Last Updated: 9 Jan 2018

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