Autoimmune retinopathy

Common Name(s)

Autoimmune retinopathy

Autoimmune retinopathy represents a spectrum of rare autoimmune diseases that primarily affect retinal photoreceptor function and lead to progressive vision loss. Included in this spectrum are cancer-associated retinopathy (CAR), melanoma-associated retinopathy (MAR) and presumed non-paraneoplastic autoimmune retinopathy (npAIR). Autoimmune retinopathy typically presents in the fifth and sixth decades with rapidly progressive, bilateral, painless visual deterioration. Examination of the fundus (the back inner part of the eye) is usually normal at presentation. The underlying reason for the autoimmune attack on retinal cells remains unknown. Treatment includes systemic immunosuppression with steroid and steroid-sparing agents, intravenous immunoglobulin (IVIG), and plasmapheresis (plasma exchange).  
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune retinopathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune retinopathy" returned 15 free, full-text research articles on human participants. First 3 results:

B Cell Anomalies in Autoimmune Retinopathy (AIR).
 

Author(s): Elena Stansky, Angélique Biancotto, Pradeep K Dagur, Sapna Gangaputra, Benjamin Chaigne-Delalande, Robert B Nussenblatt, H Nida Sen, J Philip McCoy

Journal: Invest. Ophthalmol. Vis. Sci.. 2017 Jul;58(9):3600-3607.

 

Autoimmune retinopathy (AIR) is a retinopathy associated with unexplained vision loss presumably linked to circulating antiretinal antibodies; currently, however, there are no standardized criteria regarding the diagnosis, treatment strategy, or pathogenesis of this disease. The importance ...

Last Updated: 31 Dec 1969

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Antiretinal antibody- proven autoimmune retinopathy.
 

Author(s): Sharanya Abraham, S Sudharshan, Muna Bhende, Sudha K Ganesh, Sriram Gopal

Journal: Indian J Ophthalmol. 2017 May;65(5):416-420.

 

A young female presented with bilateral subacute onset of progressive decrease in night vision and reduced peripheral field of vision. The short duration and rapid progression of symptoms along with the lack of family history of night blindness prompted a diagnosis of autoimmune retinopathy ...

Last Updated: 31 Dec 1969

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Serum Autoantibody Profiling of Patients with Paraneoplastic and Non-Paraneoplastic Autoimmune Retinopathy.
 

Author(s): Josianne C Ten Berge, Joost van Rosmalen, Jacolien Vermeer, Cecilia Hellström, Cecilia Lindskog, Peter Nilsson, Ulrika Qundos, Aniki Rothova, Marco W J Schreurs

Journal:

 

Although multiple serum antiretinal autoantibodies (ARAs) have been reported in patients with paraneoplastic and non-paraneoplastic autoimmune retinopathy ((n)pAIR), not all retinal antigens involved in (n)pAIR are specified. This study aims to serologically identify patients with ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune retinopathy" returned 3 free, full-text review articles on human participants. First 3 results:

The enigma of autoimmune retinopathy.
 

Author(s): Farzin Forooghian, Sijia Cao, Jing Cui, Joanne A Matsubara

Journal: Int Ophthalmol Clin. 2015 ;55(2):81-91.

 

Last Updated: 31 Dec 1969

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Autoimmune retinopathy.
 

Author(s): Landon Grange, Monica Dalal, Robert B Nussenblatt, H Nida Sen

Journal: Am. J. Ophthalmol.. 2014 Feb;157(2):266-272.e1.

 

To provide a detailed review of current clinical guidelines for the diagnosis, work-up and treatment of autoimmune retinopathy and to preview briefly possible future therapies.

Last Updated: 31 Dec 1969

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Autoimmune retinopathy.
 

Author(s): T Braithwaite, A Vugler, A Tufail

Journal: Ophthalmologica. 2012 ;228(3):131-42.

 

Autoimmune retinopathy encompasses a spectrum of rare autoimmune diseases that primarily affect retinal photoreceptor function, and include cancer-associated retinopathy (CAR), melanoma-associated retinopathy (MAR) and presumed non-paraneoplastic autoimmune retinopathy (npAIR). Autoimmune ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.