Bare Lymphocyte Syndrome

Common Name(s)

Bare Lymphocyte Syndrome, Bare lymphocyte syndrome type 1

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bare Lymphocyte Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bare Lymphocyte Syndrome" returned 19 free, full-text research articles on human participants. First 3 results:

Disseminated Bacillus Calmette-Guérin (BCG) infection following allogeneic hematopoietic stem cell transplant in a patient with Bare Lymphocyte Syndrome type II.
 

Author(s): R F Abu-Arja, B E Gonzalez, M R Jacobs, L Cabral, R Egler, J Auletta, J Arnold, K R Cooke

Journal: Transpl Infect Dis. 2014 Oct;16(5):830-7.

 

We describe the first case, to our knowledge, of disseminated Mycobacterium bovis Bacillus Calmette-Guérin infection in a child with Bare Lymphocyte Syndrome type II after undergoing hematopoietic stem cell transplantation (HSCT). The patient presented 30 days post HSCT with fever ...

Last Updated: 11 Oct 2014

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). 1993.
 

Author(s): Viktor Steimle, Luc A Otten, Madeleine Zufferey, Bernard Mach

Journal: J. Immunol.. 2007 Jun;178(11):6677-88.

 

Last Updated: 21 May 2007

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A subject with a novel type I bare lymphocyte syndrome has tapasin deficiency due to deletion of 4 exons by Alu-mediated recombination.
 

Author(s): Toshio Yabe, Sumiyo Kawamura, Masako Sato, Koichi Kashiwase, Hidenori Tanaka, Yoshihide Ishikawa, Yoji Asao, Junko Oyama, Kazuma Tsuruta, Katsushi Tokunaga, Kenji Tadokoro, Takeo Juji

Journal: Blood. 2002 Aug;100(4):1496-8.

 

HLA class I expression depends on the formation of a peptide-loading complex composed of class I heavy chain; beta(2)-microglobulin; the transporter associated with antigen processing (TAP); and tapasin, which links TAP to the heavy chain. Defects in TAP result in a class I deficiency ...

Last Updated: 31 Jul 2002

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bare Lymphocyte Syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

[Molecular basis of HLA class-I deficiency and bare lymphocyte syndrome (BLS)].
 

Author(s): Michał Dzik, Maria Majdan

Journal: Postepy Hig Med Dosw (Online). 2005 ;59():245-9.

 

Molecules of human leukocyte HLA class I antigens play a crucial role in the presentation of endogenic peptides, allowing effector cells of the immune system to control the immune homeostasis of the host. There are rare immunodeficiencies which result in impaired HLA antigen expression ...

Last Updated: 4 Jul 2005

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The bare lymphocyte syndrome: molecular clues to the transcriptional regulation of major histocompatibility complex class II genes.
 

Author(s): A DeSandro, U M Nagarajan, J M Boss

Journal: Am. J. Hum. Genet.. 1999 Aug;65(2):279-86.

 

Last Updated: 20 Aug 1999

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
 

Status: Recruiting

Condition Summary: SCID; Omenn's Syndrome; Reticular Dysgenesis; Wiskott-Aldrich Syndrome; Bare Lymphocyte Syndrome; Common Variable Immunodeficiency; Chronic Granulomatous Disease; CD40 Ligand Deficiency; Hyper IgM Syndrome; X-linked Lymphoproliferative Disease; Hemophagocytic Lymphohistiocytosis; Griscelli Syndrome; Chediak-Higashi Syndrome; Langerhan's Cell Histiocytosis

 

Last Updated: 4 Oct 2017

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Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
 

Status: Recruiting

Condition Summary: Primary Immunodeficiency (PID); Congenital Bone Marrow Failure Syndromes; Inherited Metabolic Disorders (IMD); Hereditary Anemias; Inflammatory Conditions

 

Last Updated: 25 Oct 2017

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