Bile acid malabsorption, primary

Common Name(s)

Bile acid malabsorption, primary

Primary bile acid malabsorption is an intestinal disorder associated with chronic watery diarrhea, excess fecal bile acids, and steatorrhea. Bile acid malabsorption has been classified into 3 main types depending on the etiology. Types 1 and 3 are secondary disorders: type 1 is due to ileal dysfunction resulting from Crohn disease or ileal resection, and type 3 is secondary to other conditions, including cholecystectomy, post-vagotomy, celiac disease, and pancreatic insufficiency. Type 2 bile acid malabsorption is a primary congenital disorder, including the rare type due to mutations in the SLC10A2 gene (review by {8:Pattni and Walters, 2009}).
 

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Clinical Trial Information This information is provided by ClinicalTrials.gov

To Assess Safety, Tolerability and Efficacy of LJN452 in Patients With Primary Bile Acid Diarrhea.
 

Status: Recruiting

Condition Summary: Primary Bile Acid Diarrhea

 

Last Updated: 10 Nov 2016

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