Biliary Atresia

Common Name(s)

Biliary Atresia

Biliary Atresia is a digestive disorder characterized by the incomplete development of the bile duct system. The bile duct system is responsible for storing and transporting bile from the liver, where it is made, to the intestines, where it helps to digest food. Incomplete development of the ducts inhibits the flow of bile. Individuals with this defect have digestion problems as well as a yellow discoloration of the eye and skin (jaundice). Doctors diagnose this defect early in life, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. Digestion specialists may suggest individuals eat a lower-fat diet, or undergo surgery to relieve the blockage or create a tube to allow bile to reach the digestive system.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Biliary Atresia" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Biliary Atresia" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Biliary Atresia" returned 321 free, full-text research articles on human participants. First 3 results:

Stool Color Card as a Screening Tool for Biliary Atresia.
 

Author(s): Siba Prosad Paul, Jagrati Chopra

Journal: Indian Pediatr. 2018 04;55(4):346.

 

Last Updated: 31 Dec 1969

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Endoscopic retrograde cholangiopancreatography in adult patients with biliary atresia: PROCESS-compliant case series.
 

Author(s): Jong Jin Hyun, Shayan S Irani, Richard A Kozarek

Journal: Medicine (Baltimore). 2018 May;97(18):e0603.

 

Biliary atresia is a progressive inflammatory disease of the bile duct that eventually results in biliary cirrhosis. It is a rare neonatal disease that mandates treatment within the first 2 years of life in order for the infant to survive. Patients usually undergo palliative Kasai ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Biliary Atresia" returned 38 free, full-text review articles on human participants. First 3 results:

Update on investigations pertaining to the pathogenesis of biliary atresia.
 

Author(s): Alexandra Kilgore, Cara L Mack

Journal: Pediatr. Surg. Int.. 2017 Dec;33(12):1233-1241.

 

Biliary atresia is a devastating biliary disease of neonates that results in liver transplantation for the vast majority. The etiology of biliary atresia is unknown and is likely multifactorial, with components of genetic predisposition, environmental trigger and autoimmunity contributing ...

Last Updated: 31 Dec 1969

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Biliary atresia: Indications and timing of liver transplantation and optimization of pretransplant care.
 

Author(s): Shikha S Sundaram, Cara L Mack, Amy G Feldman, Ronald J Sokol

Journal: Liver Transpl.. 2017 01;23(1):96-109.

 

Biliary atresia (BA) is a progressive, fibro-obliterative disorder of the intrahepatic and extrahepatic bile ducts in infancy. The majority of affected children will eventually develop end-stage liver disease and require liver transplantation (LT). Indications for LT in BA include ...

Last Updated: 31 Dec 1969

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Steroids after the Kasai procedure for biliary atresia: the effect of age at Kasai portoenterostomy.
 

Author(s): Athanasios Tyraskis, Mark Davenport

Journal: Pediatr. Surg. Int.. 2016 Mar;32(3):193-200.

 

The use of adjuvant steroids following Kasai porteoenterostomy (KPE) for biliary atresia is controversial. The aim of this study was twofold: a systematic review of published literature and an update of the clinical Kings College Hospital series to look for evidence of an effect of ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy
 

Status: Recruiting

Condition Summary: Biliary Atresia

 

Last Updated: 11 Jun 2018

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Mapping Disease Pathways for Biliary Atresia
 

Status: Recruiting

Condition Summary: Biliary Atresia

 

Last Updated: 3 Jul 2018

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Pentoxifylline Therapy in Biliary Atresia
 

Status: Recruiting

Condition Summary: Biliary Atresia

 

Last Updated: 12 Sep 2017

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