Brugada Syndrome 3

Common Name(s)

Brugada Syndrome 3

Brugada syndrome is characterized by an ST segment elevation in the right precordial electrocardiogram leads (so-called type 1 ECG) and a high incidence of sudden death in patients with structurally normal hearts. The syndrome typically manifests during adulthood, with a mean age of sudden death of 41 +/- 15 years, but also occurs in infants and children (summary by {1:Antzelevitch et al., 2005}). For a discussion of the genetic heterogeneity of Brugada syndrome, see BRGDA1 ({601144}).
 

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Condition Specific Organizations

Following organizations serve the condition "Brugada Syndrome 3" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brugada Syndrome 3" returned 10 free, full-text research articles on human participants. First 3 results:

Last Updated: 31 Dec 1969

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Long-QT Syndrome, Brugada Syndrome, and Catecholaminergic Polymorphic Ventricular Tachycardia: A Tale of 3 Diseases.
 

Author(s): Salvatore Patanè

Journal: J. Am. Coll. Cardiol.. 2016 06;67(23):2805.

 

Last Updated: 31 Dec 1969

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Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function.
 

Author(s): Tao You, Weike Mao, Benzhi Cai, Faqian Li, Haodong Xu

Journal: Int. J. Mol. Med.. 2015 Jul;36(1):309-15.

 

The human cardiac fast transient outward K+ channel is composed of the KV4.3 α subunit encoded by KCND3 and the K+ channel‑interacting protein 2 (KChIP2) β subunit, and determines the early repolarization of the action potential (AP). Two human mutations (G600R and L450F) in KV4.3 ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

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The terms "Brugada Syndrome 3" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Worm Study: Modifier Genes in Sudden Cardiac Death
 

Status: Recruiting

Condition Summary: Brugada Syndrome; Long QT Syndrome 3

 

Last Updated: 13 May 2015

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