Brugada Syndrome

Common Name(s)

Brugada Syndrome

Brugada syndrome is a condition that causes a disruption of the heart's normal rhythm (arrhythmia). Signs and symptoms usually develop in adulthood and include ventricular arrhythmia that can cause fainting, seizures, difficulty breathing, or sudden death. These complications often occur when an affected person is resting or asleep. Brugada syndrome is inherited in an autosomal dominant manner and may be caused by a mutation in any of several genes (most commonly the SCN5A gene). In many cases, the genetic cause is not identified. There have also been reports of acquired Brugada syndrome which have been associated with adverse reactions to certain drugs or other substances. Treatment may include use of an implantable cardioverter defibrillator (ICD) in people with a history of fainting or heart attack.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brugada Syndrome" for support, advocacy or research.

SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

Last Updated: 23 Apr 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brugada Syndrome" for support, advocacy or research.

SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

http://www.StopSADS.org

Last Updated: 23 Apr 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

SADS Foundation Website

Information on living with SADS, diagnosis, treatment, prevention, and advocacy/education.

Updated 29 Apr 2014

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brugada Syndrome" returned 333 free, full-text research articles on human participants. First 3 results:

Cohort of Patients Referred for Brugada Syndrome Investigation in an Electrophysiology Service - 19-Year Registry.
 

Author(s): Alvaro Valentim Lima Sarabanda

Journal: Arq. Bras. Cardiol.. 2018 07;111(1):19-20.

 

Last Updated: 31 Dec 1969

Go To URL
Brugada syndrome in patients with acute febrile illness.
 

Author(s): Stalin Viswanathan, Rajeswari Aghoram

Journal: Indian Heart J. ;70(3):416-420.

 

Brugada syndrome (BrS) is an inherited electroclinical syndrome and can be occasionally precipitated by fever. The prevalence of Brugada-type electrocardiographic patterns (BTEP) due to febrile illnesses have not been previously studied in India.

Last Updated: 31 Dec 1969

Go To URL
Cohort of Patients Referred for Brugada Syndrome Investigation in an Electrophysiology Service - 19-Year Registry.
 

Author(s): Stefan Warpechowski Neto, Tiago Luiz Luz Leiria, Laura Lessa Gaudie Ley, Antonio Lessa Gaudie Ley, Luiza Zwan Dutra, Leonardo Martins Pires, Marcelo Lapa Kruse, Gustavo Glotz de Lima

Journal: Arq. Bras. Cardiol.. 2018 Jul;111(1):13-18.

 

Brugada syndrome (SBr) is an arrhythmic condition characterized by ST-T segment abnormalities in the right precordial leads associated with a high risk of ventricular arrhythmias and sudden death. Local data regarding the clinical characteristics of patients with a typical electrocardiographic ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brugada Syndrome" returned 47 free, full-text review articles on human participants. First 3 results:

Brugada syndrome: Diagnosis, risk stratification and management.
 

Author(s): Jean-Baptiste Gourraud, Julien Barc, Aurélie Thollet, Hervé Le Marec, Vincent Probst

Journal: Arch Cardiovasc Dis. 2017 Mar;110(3):188-195.

 

Brugada syndrome is a rare inherited arrhythmia syndrome leading to an increased risk of sudden cardiac death, despite a structurally normal heart. Diagnosis is based on a specific electrocardiogram pattern, observed either spontaneously or during a sodium channel blocker test. Among ...

Last Updated: 31 Dec 1969

Go To URL
The Brugada Syndrome - From Gene to Therapy.
 

Author(s): Antonio Curcio, Giuseppe Santarpia, Ciro Indolfi

Journal: Circ. J.. 2017 Feb;81(3):290-297.

 

It is almost a quarter of century that a pioneering work of 2 researchers named Brugada brought the entire scientific community to understanding the molecular, clinical, and electrophysiological aspects of a distinctive syndrome. It affects mainly young adults with syncope and/or ...

Last Updated: 31 Dec 1969

Go To URL
Epicardial substrate ablation for Brugada syndrome.
 

Author(s): Koonlawee Nademanee, Meleze Hocini, Michel Haïssaguerre

Journal: Heart Rhythm. 2017 03;14(3):457-461.

 

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Rhythmic Risk of Type 1 Brugada Syndrome and Pulmonary Infundibulum Mapping
 

Status: Not yet recruiting

Condition Summary: Brugada Syndrome Type 1

 

Last Updated: 19 Jun 2018

Go to URL
The Brugada Syndrome: a Follow-up Study
 

Status: Recruiting

Condition Summary: Brugada Syndrome

 

Last Updated: 26 Mar 2018

Go to URL
Ripple Mapping for Epicardial Mapping of Brugada Syndrome
 

Status: Recruiting

Condition Summary: Brugada Syndrome

 

Last Updated: 15 Feb 2018

Go to URL