Buerger Disease

Common Name(s)

Buerger Disease

Buerger disease is a disease that causes obstruction of the blood vessels of the hands and feet. It is caused by vasculitis, which is an inflammation of blood vessels. The blood vessels of the hands and feet are especially affected, becoming constricted or totally blocked. This reduces blood flow to the tissues of hands and feet, resulting in pain and eventually damage.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Buerger Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Buerger Disease" returned 12 free, full-text research articles on human participants. First 3 results:

Endothelial dysfunction in patients with Buerger disease.
 

Author(s): Kimihiro Igari, Toshifumi Kudo, Takahiro Toyofuku, Yoshinori Inoue

Journal:

 

We evaluated the endothelial function of patients with Buerger disease using peripheral arterial tonometry test, and examined the factors that are significantly correlated with the endothelial dysfunction in these patients. We performed the peripheral arterial tonometry test in 22 ...

Last Updated: 1 Sep 2017

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Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease.
 

Author(s): Akimichi Iwamoto, Masato Kajikawa, Tatsuya Maruhashi, Yumiko Iwamoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Kensuke Noma, Yoshiki Aibara, Ayumu Nakashima, Yukihito Higashi

Journal: J. Atheroscler. Thromb.. 2016 Nov;23(11):1261-1269.

 

Both vascular function and structure are independent predictors of cardiovascular events. The purpose of this study was to evaluate vascular function and structure of a leg artery in patients with peripheral artery disease (PAD).

Last Updated: 12 May 2016

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Effect of a Low-Intensity Pulsed Ultrasound Device, SX-1001, on Clinical Symptoms in Buerger Disease With Limb Ischemia.
 

Author(s): Yukihito Higashi, Nobuyoshi Azuma, Yasuchika Takeishi, Tohru Minamino, Yasuki Kihara, Koichi Node, Masataka Sata, Yoshihiro Fukumoto, Hideki Origasa, Hiroshi Matsuo, Hiroaki Naritomi, Masatoshi Fujita, Wataru Shimizu

Journal: Int Heart J. 2015 ;56(6):632-8.

 

Buerger disease is a rare disease of unknown etiology and cannot be treated by bypass surgery or percutaneous re-endovascularization. Although the need for effective limb ischemia prevention strategies is increasingly being recognized, effective preventative strategies are insufficient. ...

Last Updated: 3 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Buerger Disease" returned 2 free, full-text review articles on human participants. First 3 results:

Efficacy of bosentan in patients with refractory thromboangiitis obliterans (Buerger disease): A case series and review of the literature.
 

Author(s): Javier Narváez, Carmen García-Gómez, Lorenzo Álvarez, Pilar Santo, María Aparicio, María Pascual, Mercè López de Recalde, Helena Borrell, Joan M Nolla

Journal: Medicine (Baltimore). 2016 Nov;95(48):e5511.

 

The cornerstone of therapy in thromboangiitis obliterans (TAO) is complete abstinence from tobacco. In addition to discontinuation of cigarette smoking, very few pharmacological and surgical options of controversial efficacy are available to date. New therapeutic options with greater ...

Last Updated: 30 Nov 2016

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Ischemic intestinal involvement in a patient with Buerger disease: case report and literature review.
 

Author(s): Masayoshi Kobayashi, Kimihiro Kurose, Takashi Kobata, Kenji Hida, Shigeru Sakamoto, Junichi Matsubara

Journal: J. Vasc. Surg.. 2003 Jul;38(1):170-4.

 

A 42-year-old Japanese man who had undergone amputation of the left leg below the knee because of Buerger disease required emergency thrombectomy 7 months later. He complained of acute abdominal pain after thrombectomy. At aortography the distal superior mesenteric artery and its ...

Last Updated: 4 Jul 2003

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Purified CD34+ Cells Versus Peripheral Blood Mononuclear Cells in Treatment of Critical Limb Ischemia
 

Status: Recruiting

Condition Summary: Thromboangiitis Obliterans; Arteritis; Peripheral Arterial Disease

 

Last Updated: 16 Apr 2016

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Study to Assess the Efficacy and Safety of CLBS12 in Patients With Critical Limb Ischemia (CLI)
 

Status: Not yet recruiting

Condition Summary: Critical Limb Ischemia (CLI)

 

Last Updated: 23 Jul 2015

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