Bullous Pemphigoid

Common Name(s)

Bullous Pemphigoid

Bullous pemphigoid is a skin disorder characterized by large blisters. The blisters are usually located on the arms, legs, or middle of the body. About one-third of persons with bullous pemphigoid also develop blisters in the mouth. The blisters may break open and form ulcers or open sores. It usually occurs in elderly persons and is rare in young people. Symptoms come and go. In most patients, the condition goes away within 6 years. The cause is not known, but may be related to immune system disorders.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bullous Pemphigoid" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bullous Pemphigoid" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bullous Pemphigoid" returned 360 free, full-text research articles on human participants. First 3 results:

Bullous pemphigoid associated with chronic hepatitis C virus infection in a hepatitis B virus endemic area: A case report.
 

Author(s): Hyunil Jang, Young-Joo Jin, Chang Hwi Yoon, Cheol-Woo Kim, Lucia Kim

Journal: Medicine (Baltimore). 2018 Apr;97(15):e0377.

 

Bullous pemphigoid is a type of acute or chronic autoimmune disease that involves subepidermal skin lesions with bulla formation. Although viral infections, such as, human herpes virus (HHV), human immunodeficiency virus, cytomegalovirus, Epstein-Barr virus, HHV-6, hepatitis B virus ...

Last Updated: 31 Dec 1969

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Type I Gaucher disease with bullous pemphigoid and Parkinson disease: A case report.
 

Author(s): Damien Le Peillet, Virginie Prendki, Véronique Trombert, Emmanuel Laffitte, Frédéric Assal, Jean Luc Reny, Christine Serratrice

Journal: Medicine (Baltimore). 2018 Mar;97(13):e0188.

 

Gaucher disease (GD) is a rare genetic lysosomal storage disorder inherited in an autosomal recessive pattern. GD is due to the deficiency of a lysosomal enzyme, acid beta-glucosidase (or glucocerebrosidase). Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, ...

Last Updated: 31 Dec 1969

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[Bullous pemphigoid and Parkinson's disease: about a case].
 

Author(s): Hasnaa Zaouri, Baderdine Hassam

Journal:

 

Bullous pemphigoid (BP) is an organ-specific autoimmune disease which can be associated with many pathologies including degenerative neurological diseases such as Parkinson's and Alzheimer's disease. Studies have suggested the possibility of cross-immune responses through "epitope ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bullous Pemphigoid" returned 19 free, full-text review articles on human participants. First 3 results:

A case report of bullous pemphigoid associated with a melanoma and review of the literature.
 

Author(s): Kyle T Amber, Christine M Panganiban, Dorota Korta, Sebastien de Feraudy, Kristen M Kelly, Sergei A Grando

Journal: Melanoma Res.. 2017 02;27(1):65-67.

 

The association of bullous pemphigoid with melanoma remains controversial and poorly understood. Recent studies report the presence of the bullous pemphigoid antigen, BP180, in melanoma cells, yet not normal melanocytes, suggesting an underlying mechanism for cases of melanoma-associated ...

Last Updated: 31 Dec 1969

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Mechanisms of Disease: Pemphigus and Bullous Pemphigoid.
 

Author(s): Christoph M Hammers, John R Stanley

Journal: Annu Rev Pathol. 2016 May;11():175-97.

 

Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and in pemphigoid, the basal keratinocytes lose adhesion to the basement membrane. Pemphigus lesions are mediated ...

Last Updated: 31 Dec 1969

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Three Cases of Bullous Pemphigoid Associated with Dipeptidyl Peptidase-4 Inhibitors - One due to Linagliptin.
 

Author(s): Francisco Manuel Ildefonso Mendonça, Francisco José Martín-Gutierrez, Juan José Ríos-Martín, Francisco Camacho-Martinez

Journal: Dermatology (Basel). 2016 ;232(2):249-53.

 

Bullous pemphigoid (BP) is an acquired subepidermal autoimmune blistering disease in which there are humoral and cellular responses against the BP180 and BP230 antigens. Dipeptidyl peptidase (DPP)-4 inhibitors enhance endogenous glucagon peptide-1 and glucose-dependent insulinotropic ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 6 Mar 2018

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A Proof-of-Concept Study of Topical AC-203 in Patients With Bullous Pemphigoid
 

Status: Recruiting

Condition Summary: Bullous Pemphigoid

 

Last Updated: 18 Sep 2017

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Last Updated: 15 Jul 2016

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