Invasive candidiasis

Common Name(s)

Invasive candidiasis, Candidemia

Invasive candidiasis is an infection that occurs when a type of fungus or yeast, called Candida, enters the bloodstream. The condition is called systemic candidiasis when only one organ system is involved. It is called disseminated candidiasis if the disease has spread to multiple organ systems. Candida are found naturally in many parts of the human body. When the fungus overgrows or enters other parts of the body, it can be dangerous.

Symptoms tend to vary between cases of invasive candidiasis depending on which organs are infected, but a fever is very common. Red bumps, which look like pimples without the pus, may be present as well. Depending on which organs are affected, blood clots and trouble passing urine are possible symptoms. Invasive candidiasis may also cause sepsis, which can cause damage to or failure of organ systems. In severe cases, invasive candidiasis can lead to blindness or even death. However, once diagnosed, invasive candidiasis can be treated.

Most people who suffer from invasive candidiasis contract it in a hospital, especially if they have a weakened immune system or they are recovering from surgery. Doctors will diagnose invasive candidiasis by testing to see if the yeast is present in places of the body where it is not found in healthy people, often the blood. In individuals with invasive candidiasis, levels of a carbohydrate called beta-glucan are often very high. Doctors may also test how much beta-glucan is present in your system in order to form a diagnosis.

There are multiple antifungal medications that can be prescribed to treat invasive candidiasis. Your doctor should suggest which treatment is right for you because certain types of the fungus respond differently to each medication. If you believe that you have invasive candidiasis, contact your doctor immediately. Support groups are also a good source of information and can help connect you with others affected by invasive candidiasis.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive candidiasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Invasive candidiasis" returned 118 free, full-text research articles on human participants. First 3 results:

Epidemiology, clinical characteristics, and risk factors for mortality of early- and late-onset invasive candidiasis in intensive care units in China.
 

Author(s): Yi Yang, Fengmei Guo, Yan Kang, Bin Zang, Wei Cui, Bingyu Qin, Yingzhi Qin, Qiang Fang, Tiehe Qin, Dongpo Jiang, Bojing Cai, Ruoyu Li, Haibo Qiu,

Journal: Medicine (Baltimore). 2017 Oct;96(42):e7830.

 

To identify the epidemiology, treatments, outcomes, and risk factors for patients with early- or late-onset invasive candidiasis (EOIC or LOIC) in intensive care units in China.Patients were classified as EOIC (≤10 days) or LOIC (>10 days) according to the time from hospital admission ...

Last Updated: 19 Oct 2017

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Pharmacoeconomic analysis of antifungal therapy for primary treatment of invasive candidiasis caused by Candida albicans and non-albicans Candida species.
 

Author(s): Huang-Tz Ou, Tsung-Ying Lee, Yee-Chun Chen, Claudie Charbonneau

Journal:

 

Cost-effectiveness studies of echinocandins for the treatment of invasive candidiasis, including candidemia, are rare in Asia. No study has determined whether echinocandins are cost-effective for both Candida albicans and non-albicans Candida species. There have been no economic evaluations ...

Last Updated: 11 Jul 2017

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[Clinical features of invasive candidiasis and risk factors for Candida bloodstream infection in children: a multicenter study in Urumqi, China].
 

Author(s): Ai Bi Bai Ai Er Ken, Zhi-Hua Ma, Dai-Qin Xiong, Pei-Ru Xu

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2017 Apr;19(4):414-418.

 

To investigate the clinical features of invasive candidiasis in children and the risk factors for Candida bloodstream infection.

Last Updated: 14 Apr 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Invasive candidiasis" returned 44 free, full-text review articles on human participants. First 3 results:

Diagnosis and management of invasive candidiasis in the ICU: an updated approach to an old enemy.
 

Author(s): Thierry Calandra, Jason A Roberts, Massimo Antonelli, Matteo Bassetti, Jean-Louis Vincent

Journal:

 

Invasive fungal infections, particularly those caused by Candida species, are not uncommon in critically ill patients and are associated with considerable morbidity and mortality. Diagnosis and management of these infections can be challenging. In this review, we will briefly discuss ...

Last Updated: 27 May 2016

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Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia.
 

Author(s): Yvonne Schmiedel, Stephan Zimmerli

Journal:

 

Every year, Candida, Aspergillus, Cryptococcus and Pneumocystis infect an estimated two million individuals worldwide. Most are immunocompromised or critically ill. Candida is the most common fungal pathogen of the critically ill and of recipients of transplanted abdominal organs. ...

Last Updated: 23 Feb 2016

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T2MR and T2Candida: novel technology for the rapid diagnosis of candidemia and invasive candidiasis.
 

Author(s): Michael A Pfaller, Donna M Wolk, Thomas J Lowery

Journal: Future Microbiol. 2016 ;11(1):103-17.

 

Candidemia and other forms of invasive candidiasis pose a significant diagnostic challenge. In order to provide the best treatment, it is important to accurately detect the fungal infection and identify the species. Historically, diagnosis of Candida infections depended upon three ...

Last Updated: 24 Dec 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A B-D-Glucan Driven Antifungal Stewardship Approach for Invasive Candidiasis
 

Status: Recruiting

Condition Summary: Invasive Candidiases; Abdominal Infection

 

Last Updated: 30 Mar 2017

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BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia
 

Status: Recruiting

Condition Summary: Invasive Candidiasis

 

Last Updated: 11 Jul 2017

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Pharmacokinetics of Micafungin in Children on Extracorporeal Membrane Oxygenation
 

Status: Recruiting

Condition Summary: Invasive Candidiasis

 

Last Updated: 31 May 2017

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