Coronary microvascular disease

Common Name(s)

Coronary microvascular disease, Cardiac syndrome X

Coronary microvascular disease, also known as cardiac syndrome X, is a type of heart disease. The heart is a muscle that requires nutrients and oxygen, which is supplied by blood that travels through tubes or vessels called the “coronary arteries.” When these tubes become damaged or clogged, a patient can develop coronary artery disease. Coronary artery disease (CAD) can ultimately cause a blockage of blood flow in the heart and a heart attack. Coronary microvascular disease is a type of CAD characterized by damage to the smaller coronary blood vessels, which may potentially spasm and decrease blood flow to the heart. Coronary microvascular disease commonly develops in women, especially young women. The most common symptom of coronary microvascular disease is angina, or chest pain, that lasts longer than 10 minutes and even longer than 30 minutes. Fatigue, problems sleeping and shortness of breath are also symptoms. Symptoms are usually noticed during routine activities and times of mental stress. There is no specific test for coronary microvascular disease, but stress tests and imaging are often used. Mediations such as aspirin and beta blockers are the main treatment for coronary microvascular disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Coronary microvascular disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Coronary microvascular disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Coronary microvascular disease" returned 35 free, full-text research articles on human participants. First 3 results:

Microvascular retinopathy and angiographically-demonstrated coronary artery disease: A cross-sectional, observational study.
 

Author(s): Lisa Cheng, Peter Barlis, Joel Gibson, Deb Colville, Anastasia Hutchinson, Geoff Gleeson, Ecosse Lamoureux, William VanGaal, Judy Savige

Journal:

 

Epidemiological studies suggest retinal microvascular abnormalities predict cardiac events. This study examined microvascular features associated with coronary artery abnormalities. This was a single-centre, cross-sectional, observational study of 144 consecutive subjects undergoing ...

Last Updated: 31 Dec 1969

Go To URL
Adenosine stress CMR T1-mapping detects early microvascular dysfunction in patients with type 2 diabetes mellitus without obstructive coronary artery disease.
 

Author(s): Eylem Levelt, Stefan K Piechnik, Alexander Liu, Rohan S Wijesurendra, Masliza Mahmod, Rina Ariga, Jane M Francis, Andreas Greiser, Kieran Clarke, Stefan Neubauer, Vanessa M Ferreira, Theodoros D Karamitsos

Journal:

 

Type 2 diabetes mellitus (T2DM) is associated with coronary microvascular dysfunction in the absence of obstructive coronary artery disease (CAD). Cardiovascular magnetic resonance (CMR) T1-mapping at rest and during adenosine stress can assess coronary vascular reactivity. We hypothesised ...

Last Updated: 31 Dec 1969

Go To URL
Body Mass Index Is Associated With Microvascular Endothelial Dysfunction in Patients With Treated Metabolic Risk Factors and Suspected Coronary Artery Disease.
 

Author(s): Dirk J van der Heijden, Maarten A H van Leeuwen, Gladys N Janssens, Mattie J Lenzen, Peter M van de Ven, Etto C Eringa, Niels van Royen

Journal:

 

Obesity is key feature of the metabolic syndrome and is associated with high cardiovascular morbidity and mortality. Obesity is associated with macrovascular endothelial dysfunction, a determinant of outcome in patients with coronary artery disease. Here, we compared the influence ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Coronary microvascular disease" returned 7 free, full-text review articles on human participants. First 3 results:

Microvascular coronary dysfunction and ischemic heart disease: where are we in 2014?
 

Author(s): John W Petersen, Carl J Pepine

Journal: Trends Cardiovasc. Med.. 2015 Feb;25(2):98-103.

 

Many patients with angina and signs of myocardial ischemia on stress testing have no significant obstructive epicardial coronary disease. There are many potential coronary and non-coronary mechanisms for ischemia without obstructive epicardial coronary disease, and prominent among ...

Last Updated: 31 Dec 1969

Go To URL
Obesity and coronary microvascular disease - implications for adipose tissue-mediated remote inflammatory response.
 

Author(s): Zsolt Bagi, Zuzana Broskova, Attila Feher

Journal: Curr Vasc Pharmacol. 2014 May;12(3):453-61.

 

It is believed that obesity has detrimental effects on the coronary circulation. These include immediate changes in coronary arterial vasomotor responsiveness and the development of occlusive large coronary artery disease. Despite its critical role in regulating myocardial perfusion, ...

Last Updated: 31 Dec 1969

Go To URL
Coronary microvascular disease in chronic Chagas cardiomyopathy including an overview on history, pathology, and other proposed pathogenic mechanisms.
 

Author(s): Marcos A Rossi, Herbert B Tanowitz, Lygia M Malvestio, Mara R Celes, Erica C Campos, Valdecir Blefari, Cibele M Prado

Journal:

 

This review focuses on the short and bewildered history of Brazilian scientist Carlos Chagas's discovery and subsequent developments, the anatomopathological features of chronic Chagas cardiomyopathy (CCC), an overview on the controversies surrounding theories concerning its pathogenesis, ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Coronary Artery Disease and Coronary Microvascular Disease in Cardiomyopathies Registry
 

Status: Recruiting

Condition Summary: Hypertrophic; Ischemic; Restrictive Cardiomyopathy; Dilated Cardiomyopathies

 

Last Updated: 9 Apr 2018

Go to URL
Whole-Heart Myocardial Blood Flow Quantification Using MRI
 

Status: Recruiting

Condition Summary: Coronary Artery Disease; Coronary Microvascular Disease

 

Last Updated: 9 Mar 2018

Go to URL
Comprehensive Treatment of Angina in Women With Microvascular Dysfunction
 

Status: Recruiting

Condition Summary: Angina Pectoris; Coronary Microvascular Disease

 

Last Updated: 13 Feb 2017

Go to URL