Carotid artery disease

Common Name(s)

Carotid artery disease

Carotid artery disease is a condition characterized by the narrowing of the arteries located between the heart and the head (carotid arteries). The narrowing is caused by a buildup of a fatty substance (plaque) on the walls of the arteries (atherosclerosis). This situation is very dangerous because blood flow to the brain can be reduced or even stopped, causing a stroke. When having a stroke, the brain does not get enough oxygen. Strokes are common causes of permanent disability and death.

Unfortunately, there are not many symptoms of the early stages of the disease. Many people will not know they have the disease until they have a stroke. Sometimes blood flow to the brain will only be blocked temporarily and will cause a “mini-stroke” (transient ischemic attack or TIA). Symptoms of strokes and TIAs include: trouble seeing or speaking, dizziness, severe headaches, and sudden weakness or numbness in the face and limbs, usually only affecting one side of the body.

There are many risk factors for carotid artery disease. The disease is more common in older individuals. Carotid artery disease is also more common if there is a family history of the disease. Other risk factors include obesity, smoking, high blood pressure, lack of exercise, diabetes, and high blood-fat levels. If you have spells where you stop breathing at night (sleep apnea), you also may be at risk of a stroke.

To diagnose carotid artery disease, your doctor will ask you about your family’s medical history and perform a physical exam. They may also use imaging tests, such as ultrasounds and MRIs, to get a better view of your arteries. Treatment of carotid artery disease may include healthy lifestyle changes, medication, or surgery. Research is ongoing, so if you have been diagnosed with coronary artery disease, talk to your doctor and specialists about the most current treatment options. Support groups can help connect you with others living with coronary artery disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Carotid artery disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Carotid artery disease" returned 364 free, full-text research articles on human participants. First 3 results:

Carotid arterial wall inflammation in peripheral artery disease is augmented by type 2 diabetes: a cross-sectional study.
 

Author(s): Sophie J Bernelot Moens, Robert M Stoekenbroek, Fleur M van der Valk, Simone L Verweij, Mark J W Koelemay, Hein J Verberne, Max Nieuwdorp, Erik S G Stroes

Journal:

 

Patients with peripheral artery disease (PAD) are at increased risk of secondary events, which is exaggerated in the presence of type 2 diabetes mellitus. Diabetes is associated with a systemic pro-inflammatory state. We therefore investigated the cumulative impact of PAD and type ...

Last Updated: 26 Nov 2016

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Usefulness of carotid plaque (sum and maximum of plaque thickness) in combination with intima-media thickness for the detection of coronary artery disease in asymptomatic patients with diabetes.
 

Author(s): Shoichi Akazawa, Masayuki Tojikubo, Yuko Nakano, Satoe Nakamura, Hidekazu Tamai, Koji Yonemoto, Eiji Sadasima, Tomohiro Kawasaki, Nobuhiko Koga

Journal: J Diabetes Investig. 2016 May;7(3):396-403.

 

The usefulness of markers of carotid plaque, such as sum (PS) and maximum (P-max) of the plaque thickness, in combination with intima-media thickness in the common carotid artery (CIMT) for the detection of obstructive coronary artery disease (CAD) was investigated in patients with ...

Last Updated: 22 Jun 2016

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Carotid artery wall stiffness is increased in patients with small vessel disease: A case-control study.
 

Author(s): Denisa Salihović Hajdarević, Aleksandra M Pavlović, Dzevdet Smajlović, Ana Podgorac, Zagorka Jovanović, Tamara Svabić Medjedović, Nadezda Covicković Sternić

Journal: Srp Arh Celok Lek. ;144(1-2):6-9.

 

Cerebral ischemic small-vessel disease (SVD), causing lacunar infarcts and white matter hyperintensities on brain magnetic resonance imaging (MRI), is a progressive disease associated with an increased risk of stroke, dementia and death. Increased arterial stiffness has been associated ...

Last Updated: 9 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Carotid artery disease" returned 36 free, full-text review articles on human participants. First 3 results:

Endovascular prevention and treatment of stroke related to extracranial carotid artery disease.
 

Author(s): Leonardo Rangel-Castilla, Gary B Rajah, Hakeem J Shakir, Jason M Davies, Kenneth V Snyder, Adnan H Siddiqui, Elad I Levy, L Nelson Hopkins

Journal: J Cardiovasc Surg (Torino). 2017 Feb;58(1):35-48.

 

Acute ischemic stroke (AIS) is the leading cause of premature mortality and morbidity worldwide for both men and women. Extracranial carotid artery stenosis/occlusion is responsible for approximately 11.5% of ischemic strokes, whereas extracranial large vessel disease comprises roughly ...

Last Updated: 6 Dec 2016

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Asymptomatic carotid artery disease: A personalized approach to management.
 

Author(s): Aldo L Schenone, Aaron Cohen, Mehdi H Shishehbor

Journal: Cleve Clin J Med. 2015 Dec;82(12):855-63.

 

Asymptomatic carotid artery disease is relatively common and poses a challenge for internists as well as vascular specialists when deciding whether to pursue surgical endarterectomy, percutaneous stenting, or medical therapy alone. The authors review the management of asymptomatic ...

Last Updated: 15 Dec 2015

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Management of extracranial carotid artery disease.
 

Author(s): Yinn Cher Ooi, Nestor R Gonzalez

Journal: Cardiol Clin. 2015 Feb;33(1):1-35.

 

Stroke is the third leading cause of death in developed nations. Up to 88% of strokes are ischemic in nature. Extracranial carotid artery atherosclerotic disease is the third leading cause of ischemic stroke in the general population and the second most common nontraumatic cause among ...

Last Updated: 2 Dec 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 12 Jun 2017

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SVS VQI TransCarotid Revascularization Surveillance Project
 

Status: Recruiting

Condition Summary: Carotid Artery Disease

 

Last Updated: 7 Feb 2017

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The CREST-2 Registry
 

Status: Recruiting

Condition Summary: Carotid Artery Diseases

 

Last Updated: 7 Sep 2017

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