Catastrophic Antiphospholipid Syndrome

Common Name(s)

Catastrophic Antiphospholipid Syndrome

Catastrophic Antiphospholipid Syndrome is a disease that affects the small vessels, or tubes that carry blood, found in your body. Although the precise cause of this disorder is not fully understood, trauma, infection, and surgery have been identified as potential triggers of the condition. Catastrophic Antiphospholipid Syndrome can cause blockages in the vessels within the body, leading to symptoms such as chest and abdominal pain and bluish coloring of the skin (cyanosis). This condition is diagnosed based on blood tests (e.g. antibody levels and antiphospholipid antibody test). Treatments for Catastrophic Antiphosholipid Syndrome include the use of medications such as antibiotics, which fight infections, and anticoagulants, which work to preventing the formation of blockages in your vessels.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Catastrophic Antiphospholipid Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Catastrophic Antiphospholipid Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Catastrophic Antiphospholipid Syndrome" returned 62 free, full-text research articles on human participants. First 3 results:

Eculizumab in a pregnant patient with laboratory onset of catastrophic antiphospholipid syndrome: A case report.
 

Author(s): Patrizia Rovere-Querini, Valentina Canti, Roberta Erra, Esperia Bianchi, Giorgio Slaviero, Armando D'Angelo, Susanna Rosa, Massimo Candiani, Maria Teresa Castiglioni

Journal: Medicine (Baltimore). 2018 Oct;97(40):e12584.

 

Hypercoagulability and pregnancy morbidity are hallmarks of the antiphospholipid syndrome (APS). Catastrophic antiphospholipid syndrome (CAPS) is a potentially life-threatening omplication of APS, with widespread acute thrombotic microangiopathy (TMA) that can be precipitated by pregnancy ...

Last Updated: 31 Dec 1969

Go To URL
["Seronegative" catastrophic antiphospholipid syndrome in pediatrics: Clinical case].
 

Author(s): Ericka Vargas-Quevedo, Eduardo Ordoñez-Gutiérrez, Jorge Enrique Trejo-Gómora, Lénica Anahí Chávez-Aguilar, Rubén Peña-Vélez

Journal: Rev Chil Pediatr. 2018 Apr;89(2):236-240.

 

The antiphospholipid syndrome is an acquired autoimmune thrombophilia, characterized by arterial and/or venous thrombosis. Rarely, this condition can have a catastrophic presenta tion, with high mortality, and presence of microangiopathy and involvement of three or more organs.

Last Updated: 31 Dec 1969

Go To URL
Successful Treatment of Catastrophic Antiphospholipid Antibody Syndrome Associated with MALT Lymphoma by Autologous Hematopoietic Stem Cell Transplantation.
 

Author(s): Satoko Oka, Kazuo Ono, Masaharu Nohgawa

Journal: Intern. Med.. 2017 ;56(10):1207-1212.

 

A 37-year-old woman with extranodal marginal-zone lymphoma was admitted with a fever, hemiplegia, and severe dyspnea after chemotherapy. Catastrophic antiphospholipid antibody syndrome (CAPS) was suspected based on the histopathological confirmation of small-pulmonary vessel occlusion, ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Catastrophic Antiphospholipid Syndrome" returned 15 free, full-text review articles on human participants. First 3 results:

Catastrophic antiphospholipid syndrome. Case report and literature review
 

Author(s): Luis del Carpio-Orantes, Chantall Citlally Martínez-Anaya, Elías Bonilla-Casas

Journal: Gac Med Mex. 2017 ;153(4):531-536.

 

The present document is the report of a case of a very rare clinical entity, which presents with acute multiorganic failure after a thrombotic storm related to antiphospholipid antibodies, the so-called catastrophic antiphospholipid syndrome, which began as a recurrent picture of ...

Last Updated: 31 Dec 1969

Go To URL
Treatment of catastrophic antiphospholipid syndrome.
 

Author(s): Nayef M Kazzaz, W Joseph McCune, Jason S Knight

Journal: Curr Opin Rheumatol. 2016 May;28(3):218-27.

 

Catastrophic antiphospholipid syndrome (CAPS) is a severe manifestation of antiphospholipid syndrome (APS). Although affecting only 1% of patients with APS, the condition is frequently fatal if not recognized and treated early. Here, we will review the current approach to diagnosis ...

Last Updated: 31 Dec 1969

Go To URL
Catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus treated with rituximab: case report and a review of the literature.
 

Author(s): G Sukara, M Baresic, M Sentic, L Brcic, B Anic

Journal: Acta Reumatol Port. ;40(2):169-75.

 

Catastrophic antiphospholipid syndrome (CAPS) is a rare, acute, life-threatening form of antiphospholipid syndrome. In the last several decades there has been a significant improvement in the treatment of patients with CAPS, but the overall mortality is still very significant. The ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.