Cerebellar Ataxia

Common Name(s)

Cerebellar Ataxia

Cerebellar Ataxia is a condition in which damage, degeneration, or loss of nerve cells in the cerebellum (part of the brain that controls movement), results in balance problems and difficulty coordinating complex movements (ataxia). Cerebellar ataxia can be caused by: spinal cord or nerve damage, head trauma, stroke, cerebral palsy, multiple sclerosis, tumors, or complications from chickenpox. Symptoms of this condition may include poor coordination, change in speech, involuntary eye movements, and difficulty with fine motor skills. There is no specific treatment for this condition, but symptoms can be alleviated by using adaptive devices (such as canes or modified eating utensils), and therapy (physical, speech, etc.).

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cerebellar Ataxia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cerebellar Ataxia" returned 305 free, full-text research articles on human participants. First 3 results:

A Rare Case of Cerebellar Ataxia Due to Voltage-Gated Calcium Channel and Glutamic Acid Decarboxylase Autoantibodies.
 

Author(s): Giuseppe Annunziata, Pamela Lobo, Cristian Carbuccia

Journal:

 

BACKGROUND Autoimmune cerebellar ataxia can be paraneoplastic in nature or can occasionally present without evidence of an ongoing malignancy. The detection of specific autoantibodies has been statistically linked to different etiologies. CASE REPORT A 55-year-old African-American ...

Last Updated: 31 Dec 1969

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A Mild Form of COG5 Defect Showing Early-Childhood-Onset Friedreich's-Ataxia-Like Phenotypes with Isolated Cerebellar Atrophy.
 

Author(s): Young Ok Kim, Misun Yun, Jae Ho Jeong, Seong Min Choi, Seul Kee Kim, Woong Yoon, Chungoo Park, Yeongjin Hong, Young Jong Woo

Journal: J. Korean Med. Sci.. 2017 Nov;32(11):1885-1890.

 

Progressive cerebellar ataxias are rare diseases during childhood, especially under 6 years of age. In a single family, three affected siblings exhibited Friedreich's-ataxia-like phenotypes before 2 years of age. They had progressive cerebellar atrophy, intellectual disability, and ...

Last Updated: 31 Dec 1969

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Cerebellar ataxia and intrathecal baclofen therapy: Focus on patients┬┤ experiences.
 

Author(s): Shala Ghaderi Berntsson, Anne-Marie Landtblom, Gullvi Flensner

Journal:

 

Elucidating patients┬┤ experiences of living with chronic progressive hereditary ataxia and the symptomatic treatment with intrathecal baclofen (ITB) is the objective of the current study. A multicenter qualitative study with four patients included due to the rare combination of hereditary ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cerebellar Ataxia" returned 19 free, full-text review articles on human participants. First 3 results:

Does modulation of the endocannabinoid system have potential therapeutic utility in cerebellar ataxia?
 

Author(s): G J Stephens

Journal: J. Physiol. (Lond.). 2016 08;594(16):4631-41.

 

Cerebellar ataxias represent a spectrum of disorders which are, however, linked by common symptoms of motor incoordination and typically associated with deficiency in Purkinje cell firing activity and, often, degeneration. Cerebellar ataxias currently lack a curative agent. The endocannabinoid ...

Last Updated: 31 Dec 1969

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Are Type 1 metabotropic glutamate receptors a viable therapeutic target for the treatment of cerebellar ataxia?
 

Author(s): Emmet M Power, Natalya A English, Ruth M Empson

Journal: J. Physiol. (Lond.). 2016 08;594(16):4643-52.

 

The cerebellum is a key brain structure for accurate coordination of sensory and motor function. Compared with other brain regions, the cerebellum expresses a particularly high level of Type 1 metabotropic glutamate receptors (mGluR1). In this review we aim to explore the significance ...

Last Updated: 31 Dec 1969

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'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: Anti-Yo/CDR2, anti-Nb/AP3B2, PCA-2, anti-Tr/DNER, other antibodies, diagnostic pitfalls, summary and outlook.
 

Author(s): S Jarius, B Wildemann

Journal:

 

Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis. While some of them target nuclear antigens present in all or most CNS ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Deep Brain Stimulation of the Dentate Nucleus on Cerebellar Ataxia
 

Status: Recruiting

Condition Summary: Cerebellar Ataxia

 

Last Updated: 13 Nov 2017

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Cerebellar Non-invasive Stimulation in Ataxias
 

Status: Recruiting

Condition Summary: Cerebellar Ataxia

 

Last Updated: 7 Jul 2017

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