Chagas Disease

Common Name(s)

Chagas Disease, American trypanosomiasis

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 1210 free, full-text research articles on human participants. First 3 results:

Characteristics of Patients for Whom Benznidazole Was Released Through the CDC-Sponsored Investigational New Drug Program for Treatment of Chagas Disease - United States, 2011-2018.
 

Author(s): Barbara L Herwaldt, Cindy P Dougherty, Christopher K Allen, Julian P Jolly, Megan N Brown, Patricia Yu, Yon Yu

Journal:

 

Chagas disease (also known as American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi (1,2). Vectorborne transmission via skin or mucosal contact with the feces of infected triatomine bugs mainly occurs in rural areas of Latin America but has been reported ...

Last Updated: 31 Dec 1969

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Chagas Disease Surveillance Activities - Seven States, 2017.
 

Author(s): Carolyne Bennett, Anne Straily, Dirk Haselow, Susan Weinstein, Richard Taffner, Hayley Yaglom, Kenneth Komatsu, Heather Venkat, Catherine Brown, Paul Byers, John Dunn, Abelardo Moncayo, Bonny C Mayes, Susan P Montgomery

Journal:

 

Chagas disease, a potentially life-threatening disease caused by the protozoan parasite Trypanosoma cruzi, has become a concern in the United States as a result of human emigration from Latin America where Chagas disease is endemic (1). It is estimated that as many as 8 million people ...

Last Updated: 31 Dec 1969

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Atrial fibrillation in acute Chagas disease acquired via oral transmission: a case report.
 

Author(s): Paulo Fernando Pimenta de Souza, Rosane Cheble Domingues Pine, Francisco Lúzio de Paula Ramos, Ana Yecê das Neves Pinto

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):397-400.

 

Atrial fibrillation (AF), a type of supraventricular arrhythmia increases the risk of thromboembolism. Chagas disease has been reported in the Brazilian Amazon region over approximately 20 years. Cardiac abnormalities are recorded in at least 50% of patients and among these, 3.3% ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 150 free, full-text review articles on human participants. First 3 results:

Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis.
 

Author(s): Lyda Z Rojas, Marija Glisic, Laura Pletsch-Borba, Luis E Echeverría, Wichor M Bramer, Arjola Bano, Najada Stringa, Asija Zaciragic, Bledar Kraja, Eralda Asllanaj, Rajiv Chowdhury, Carlos A Morillo, Oscar L Rueda-Ochoa, Oscar H Franco, Taulant Muka

Journal:

 

Chagas disease (CD) is a major public health concern in Latin America and a potentially serious emerging threat in non-endemic countries. Although the association between CD and cardiac abnormalities is widely reported, study design diversity, sample size and quality challenge the ...

Last Updated: 31 Dec 1969

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Biosensors to Diagnose Chagas Disease: A Brief Review.
 

Author(s): María-Isabel Rocha-Gaso, Luis-Jesús Villarreal-Gómez, Denis Beyssen, Frédéric Sarry, Marco-Antonio Reyna, Carlos-Napoleón Ibarra-Cerdeña

Journal:

 

Chagas disease (CD), which mostly affects those living in deprived areas, has become one of Latin America's main public health problems. Effective prevention of the disease requires early diagnosis, initiation of therapy, and regular blood monitoring of the infected individual. However, ...

Last Updated: 31 Dec 1969

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American trypanosomiasis, or Chagas disease, in Panama: a chronological synopsis of ecological and epidemiological research.
 

Author(s): Indra G Rodriguez, Jose R Loaiza

Journal:

 

American trypanosomiasis, or Chagas disease, is a growing public health problem in Panama, and further forest degradation due to human population growth is expected to worsen the situation. Most people infected with the parasite Trypanosoma cruzi are silently ill, and their life expectancy ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Oral Fexinidazole Dosing Regimens for the Treatment of Adults With Chronic Indeterminate Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas' Disease (Chronic) Nos

 

Last Updated: 3 Jul 2018

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Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease.
 

Status: Recruiting

Condition Summary: Chagas Disease; Trypanosoma Cruzi Infection

 

Last Updated: 16 Jun 2017

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Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)
 

Status: Recruiting

Condition Summary: Chagas Disease With Heart Failure

 

Last Updated: 1 Mar 2017

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