Chiari Malformation Type 2

Common Name(s)

Chiari Malformation Type 2

Chiari malformation type 2 (CM type II) is a type of Chiari malformation in which both the cerebellum and brain stem tissue extend into the foramen magnum (the hole at the skull base for passing of the spinal cord).  This form is often accompanied by a type of spina bifida called myelomeningocele, and can also be accompanied by syringomyelia, hydrocephalus, or other abnormalities. Symptoms in infants may include stridor (wheezing sound); difficulty swallowing (dysphagia); feeding difficulties; hypotonia; and weak cry. Symptoms in children and/or adults may include headache; fatigue; loss of vision; tingling extremities; nausea; dysphagia; dizziness; muscle weakness; and ataxia. Adults and adolescents who previously had no symptoms may begin to have symptoms later in life. The exact cause of the condition is not known but it appears to be due to a developmental failure of the brain stem and upper spine. The term Arnold-Chiari malformation is technically specific to type II but may sometimes be used to describe other types of Chiari malformations.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chiari Malformation Type 2" for support, advocacy or research.

Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chiari Malformation Type 2" for support, advocacy or research.

Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chiari Malformation Type 2" returned 1 free, full-text research articles on human participants. First 3 results:

Chiari malformation Type I surgery in pediatric patients. Part 2: complications and the influence of comorbid disease in California, Florida, and New York.
 

Author(s): Jacob K Greenberg, Margaret A Olsen, Chester K Yarbrough, Travis R Ladner, Chevis N Shannon, Jay F Piccirillo, Richard C E Anderson, John C Wellons, Matthew D Smyth, Tae Sung Park, David D Limbrick

Journal: J Neurosurg Pediatr. 2016 May;17(5):525-32.

 

OBJECTIVE Chiari malformation Type I (CM-I) is a common and often debilitating pediatric neurological disease. However, efforts to guide preoperative counseling and improve outcomes research are impeded by reliance on small, single-center studies. Consequently, the objective of this ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chiari Malformation Type 2" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Arnold Chiari Malformation: the Otological Assessment as an Objective Criteria for Surgical Treatment
 

Status: Recruiting

Condition Summary: Arnold-Chiari Malformation, Type 1

 

Last Updated: 20 Dec 2017

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Genetic Analysis of the Chiari I Malformation
 

Status: Recruiting

Condition Summary: Syringomyelia; Type I Arnold Chiari Malformation

 

Last Updated: 18 Oct 2017

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