Chikungunya

Common Name(s)

Chikungunya

Chikungunya is a viral disease spread to people through the bites of infected female mosquitoes. The onset of this disease usually presents itself between four and eight days after being bitten by an infected mosquito. The first sign of infection is a fever, typically with debilitating joint pain. Other symptoms include muscle pain, headache, nausea, fatigue, and rash. Generally most people make a complete recovery, but in some cases, there may be persistent joint pain that can last for several months or even years. Additional complications may occur, including eye, neurological, and heart complications. Those with only mild symptoms may go undiagnosed, or may be misdiagnosed, especially in areas where dengue fever or other mosquito borne illnesses occur, as the same mosquito species transmit these diseases. Currently, there is no cure for the disease, and the main focus in on treatment and alleviation of symptoms. Chikungunya has been identified in about 40 countries, primarily in sub-Saharan Africa, South Asia, and Southeast Asia.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chikungunya" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chikungunya" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chikungunya" returned 742 free, full-text research articles on human participants. First 3 results:

Chikungunya virus infection, immunosuppression and respiratory tract infections: are they associated?
 

Author(s): Liliana Ríos, Alfonso J Rodriguez-Morales, Juan D Castrillón-Spitia, Valentina Henao-SanMartin, José J Londoño, Héctor D Bedoya-Rendón, Javier de Jesús Cárdenas-Pérez, Jaime A Cardona-Ospina, Guillermo J Lagos-Grisales

Journal: Int Marit Health. 2018 ;69(2):149-150.

 

Last Updated: 31 Dec 1969

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Chikungunya virus vector competency of Brazilian and Florida mosquito vectors.
 

Author(s): Nildimar Alves Honório, Keenan Wiggins, Daniel Cardoso Portela Câmara, Bradley Eastmond, Barry W Alto

Journal:

 

Chikungunya virus is a vector-borne alphavirus transmitted by the bites of infected female Ae. aegypti and Ae. albopictus. In Brazil between 2014 and 2016 almost 320 thousand autochthonous human cases were reported and in Florida numerous imported CHIKV viremic cases (> 3,800) demonstrate ...

Last Updated: 31 Dec 1969

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Persistent Replication of a Chikungunya Virus Replicon in Human Cells Is Associated with Presence of Stable Cytoplasmic Granules Containing Nonstructural Protein 3.
 

Author(s): Roland Remenyi, Yanni Gao, Ruth E Hughes, Alistair Curd, Carsten Zothner, Michelle Peckham, Andres Merits, Mark Harris

Journal:

 

Chikungunya virus (CHIKV), a mosquito-borne human pathogen, causes a disabling disease characterized by severe joint pain that can persist for weeks, months, or even years in patients. The nonstructural protein 3 (nsP3) plays essential roles during acute infection, but little is known ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chikungunya" returned 68 free, full-text review articles on human participants. First 3 results:

Treatment of chikungunya chronic arthritis: A systematic review.
 

Author(s): Gabriella Maria Pitt Gameiro Sales, Izabel Crystine Pereira Barbosa, Laura Maia Sampaio Canejo Neta, Paloma Lopes de Melo, Raphael de Azevedo Leitão, Hugo Moura de Albuquerque Melo

Journal: Rev Assoc Med Bras (1992). 2018 Jan;64(1):63-70.

 

Chikungunya (CHIK) is a tropical arbovirus, transmitted by the female mosquito Aedes aegypti and Aedes albopictus. In Brazil, there have been cases reported since 2014. The initial manifestations of this virus are sudden onset high fever, headache, chills, rashes, myalgia and intense ...

Last Updated: 31 Dec 1969

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Chikungunya virus: a rheumatologist's perspective.
 

Author(s): Marta Runowska, Dominik Majewski, Karolina Niklas, Mariusz Puszczewicz

Journal: Clin. Exp. Rheumatol.. ;36(3):494-501.

 

Chikungunya virus (CHIKV) is an arthropod-borne alphavirus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes. It is responsible for a febrile illness, typically accompanied by maculopapular rash and severe, incapacitating arthralgia. The disease, although generally self-limiting, ...

Last Updated: 31 Dec 1969

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Evidence of previous but not current transmission of chikungunya virus in southern and central Vietnam: Results from a systematic review and a seroprevalence study in four locations.
 

Author(s): Tran Minh Quan, Huynh Thi Phuong, Nguyen Ha Thao Vy, Nguyen Thi Le Thanh, Nguyen Thi Nam Lien, Tran Thi Kim Hong, Pham Ngoc Dung, Nguyen Van Vinh Chau, Maciej F Boni, Hannah E Clapham

Journal:

 

Arbovirus infections are a serious concern in tropical countries due to their high levels of transmission and morbidity. With the outbreaks of chikungunya (CHIKV) in surrounding regions in recent years and the fact that the environment in Vietnam is suitable for the vectors of CHIKV, ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Pilot Study of Chikungunya Virus Infections in Southern Taiwan
 

Status: Recruiting

Condition Summary: Chikungunya Fever

 

Last Updated: 6 Mar 2018

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Safety and Immunogenicity of a Candidate CHIKV Vaccine (CHIK001)
 

Status: Recruiting

Condition Summary: Chikungunya Fever

 

Last Updated: 2 Aug 2018

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Safety, Tolerability and Long-term Immunogenicity of Different Formulations of a Chikungunya Vaccine
 

Status: Not yet recruiting

Condition Summary: Chikungunya Virus Infection

 

Last Updated: 20 Sep 2018

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