Choledochal cysts

Common Name(s)

Choledochal cysts, Bile duct cysts

Choledochal cysts, also known as bile duct cysts, are characterized by the formation of cysts, or swelling, within the bile duct system. The bile duct system is responsible for storing and transporting bile to from the liver, where it is made, to the intestines, where it helps to digest food. Swelling within the ducts inhibits the flow of bile. Individuals with this defect have digestion problems as well as a yellow discoloration of the eye and skin (jaundice). The severity of the symptoms depends on how much swelling is observed within the duct. Doctors diagnose this defect early in life, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. Digestion specialists may suggest individuals eat a lower-fat diet, or undergo surgery to reduce the swelling of the bile duct to allow free flow of bile to the digestive system.

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Condition Specific Organizations

Following organizations serve the condition "Choledochal cysts" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Choledochal cysts" returned 29 free, full-text research articles on human participants. First 3 results:

Pediatric types I and VI choledochal cysts complicated with acute pancreatitis and spontaneous perforation: A case report and literature review.
 

Author(s): Ching-Chung Tsai, Po-Kai Huang, Hsien-Kuan Liu, Yu-Tsun Su, Ming-Chun Yang, Ming-Lun Yeh

Journal: Medicine (Baltimore). 2017 Oct;96(42):e8306.

 

Choledochal cysts are a congenital disorder of the common bile duct that can cause progressive biliary obstruction and biliary cirrhosis. They were classified by Todani into five types. Of these, type VI choledochal cysts are rarely reported in the literature.

Last Updated: 31 Dec 1969

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Reoperation After Cyst Excision with Hepaticojejunostomy for Choledochal Cysts: Our Experience in 18 Cases.
 

Author(s): Qingfeng Sheng, Zhibao Lv, Weijue Xu, Xianmin Xiao, Jiangbin Liu, Yibo Wu

Journal:

 

BACKGROUND Complete cyst excision with biliary reconstruction is the treatment of choice for choledochal cyst (CC). The aim of this article is to review our experience in patients who underwent reoperation between January 1995 and December 2014. MATERIAL AND METHODS The records of ...

Last Updated: 31 Dec 1969

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Increased survivin expression and its association with clinical parameters of congenital choledochal cysts.
 

Author(s): Z G Wu, G X Li, B Wang, Z M Chen, Q Feng

Journal:

 

The aim of the current study was to investigate survivin expression in congenital choledochal cysts (CCCs), and its associations with clinical parameters of CCCs. In total, 121 children with CCCs were included in this study as the case group, and their cysts were staged according ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Choledochal cysts" returned 11 free, full-text review articles on human participants. First 3 results:

Laparoscopic excision versus open excision for the treatment of choledochal cysts: a systematic review and meta-analysis.
 

Author(s): Chen Zhen, Zhang Xia, Li Long, Ma Lishuang, Yu Pu, Zheng Wenjuan, Li Xiaofan

Journal: Int Surg. 2015 Jan;100(1):115-22.

 

In 1723, Vater first described choledochal cyst and in 1977, Todani et al classified this disease. For many years, open excision (OP) as the standard procedure made a great impact in the treatment of choledochal cyst. Since 1995, when Farello et al first reported laparoscopic choledochal ...

Last Updated: 31 Dec 1969

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Choledochal cysts: presentation, clinical differentiation, and management.
 

Author(s): Kevin C Soares, Dean J Arnaoutakis, Ihab Kamel, Neda Rastegar, Robert Anders, Shishir Maithel, Timothy M Pawlik

Journal: J. Am. Coll. Surg.. 2014 Dec;219(6):1167-80.

 

Last Updated: 31 Dec 1969

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Risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts.
 

Author(s): Taku Ohashi, Toshifumi Wakai, Masayuki Kubota, Yasunobu Matsuda, Yuhki Arai, Toshiyuki Ohyama, Kengo Nakaya, Naoki Okuyama, Jun Sakata, Yoshio Shirai, Yoichi Ajioka

Journal: J. Gastroenterol. Hepatol.. 2013 Feb;28(2):243-7.

 

The aim of this study was to elucidate the risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Superior Bilioenteric Anastomosis by Magnetic Compressive Technique
 

Status: Recruiting

Condition Summary: Hilar Cholangiocarcinoma; Bile Duct Injury; Choledochal Cyst; Biliary Calculi

 

Last Updated: 19 Sep 2017

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UAB HRFD Core Center: Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource
 

Status: Recruiting

Condition Summary: Hepato/Renal Fibrocystic Disease; Autosomal Recessive Polycystic Kidney Disease; Joubert Syndrome; Bardet Biedl Syndrome; Meckel-Gruber Syndrome; Congenital Hepatic Fibrosis; Caroli Syndrome; Oro-Facial-Digital Syndrome Type I; Nephronophthisis; Glomerulocystic Kidney Disease

 

Last Updated: 15 Sep 2017

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