Cholera

Common Name(s)

Cholera

Cholera is caused by an infection of the intestine by the bacterium Vibrio cholerae. The illness is often mild or without symptoms, but can sometimes be severe, with symptoms typically appearing in 2-3 days. Severe symptoms are characterized by vomiting, profuse diarrhea, and leg cramps. Rapid loss of body fluids in severe cases can lead to dehydration, shock, and death within hours if left untreated. Cholera can be contracted from drinking or eating contaminated food or water. Cholera can spread quickly in areas that have poor treatment of sewage and drinking water, poor sanitation, and poor hygiene. Medical attention should be found immediately for those who think they may have cholera.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholera" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholera" returned 1339 free, full-text research articles on human participants. First 3 results:

Molecular characterization of Vibrio cholerae responsible for cholera epidemics in Uganda by PCR, MLVA and WGS.
 

Author(s): Godfrey Bwire, David A Sack, Mathieu Almeida, Shan Li, Joseph B Voeglein, Amanda Kay Debes, Atek Kagirita, Ambrose Wabwire Buyinza, Christopher Garimoi Orach, O Colin Stine

Journal:

 

For almost 50 years sub-Saharan Africa, including Uganda, has experienced several outbreaks due to Vibrio cholerae. Our aim was to determine the genetic relatedness and spread of strains responsible for cholera outbreaks in Uganda.

Last Updated: 31 Dec 1969

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Cholera Epidemic - Lusaka, Zambia, October 2017-May 2018.
 

Author(s): Nyambe Sinyange, Joan M Brunkard, Nathan Kapata, Mazyanga Lucy Mazaba, Kunda G Musonda, Raymond Hamoonga, Muzala Kapina, Fred Kapaya, Lwito Mutale, Ernest Kateule, Francis Nanzaluka, James Zulu, Chileshe Lukwesa Musyani, Alison V Winstead, William W Davis, Hammad S N'cho, Nelia L Mulambya, Patrick Sakubita, Orbie Chewe, Sulani Nyimbili, Ezinne V C Onwuekwe, Nedghie Adrien, Anna J Blackstock, Travis W Brown, Gordana Derado, Nancy Garrett, Sunkyung Kim, Sydney Hubbard, Amy M Kahler, Warren Malambo, Eric Mintz, Jennifer Murphy, Rupa Narra, Gouthami G Rao, Margaret A Riggs, Nicole Weber, Ellen Yard, Khozya D Zyambo, Nathan Bakyaita, Namani Monze, Kennedy Malama, Jabbin Mulwanda, Victor M Mukonka

Journal:

 

On October 6, 2017, an outbreak of cholera was declared in Zambia after laboratory confirmation of Vibrio cholerae O1, biotype El Tor, serotype Ogawa, from stool specimens from two patients with acute watery diarrhea. The two patients had gone to a clinic in Lusaka, the capital city, ...

Last Updated: 31 Dec 1969

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Near real-time forecasting for cholera decision making in Haiti after Hurricane Matthew.
 

Author(s): Damiano Pasetto, Flavio Finger, Anton Camacho, Francesco Grandesso, Sandra Cohuet, Joseph C Lemaitre, Andrew S Azman, Francisco J Luquero, Enrico Bertuzzo, Andrea Rinaldo

Journal:

 

Computational models of cholera transmission can provide objective insights into the course of an ongoing epidemic and aid decision making on allocation of health care resources. However, models are typically designed, calibrated and interpreted post-hoc. Here, we report the efforts ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholera" returned 74 free, full-text review articles on human participants. First 3 results:

The Cholera Epidemic in Zimbabwe, 2008-2009: A Review and Critique of the Evidence.
 

Author(s): C Nicholas Cuneo, Richard Sollom, Chris Beyrer

Journal: Health Hum Rights. 2017 Dec;19(2):249-264.

 

The 2008-2009 Zimbabwe cholera epidemic resulted in 98,585 reported cases and caused more than 4,000 deaths. In this study, we used a mixed-methods approach that combined primary qualitative data from a 2008 Physicians for Human Rights-led investigation with a systematic review and ...

Last Updated: 31 Dec 1969

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Therapeutic Potential of Cholera Toxin B Subunit for the Treatment of Inflammatory Diseases of the Mucosa.
 

Author(s): Joshua M Royal, Nobuyuki Matoba

Journal:

 

Cholera toxin B subunit (CTB) is a mucosal immunomodulatory protein that induces robust mucosal and systemic antibody responses. This well-known biological activity has been exploited in cholera prevention (as a component of Dukoral vaccine) and vaccine development for decades. On ...

Last Updated: 31 Dec 1969

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Cholera - the new strike of an old foe.
 

Author(s): Anna Kuna, MichaƂ Gajewski

Journal: Int Marit Health. 2017 ;68(3):163-167.

 

Cholera is an acute bacterial gastrointestinal infection caused by ingestion of water or food containing the pathogen Vibrio cholerae. The incubation period can be very short and it takes between several hours and 5 days. During the 19th century, cholera was spreading from India across ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Extended Dose Intervals on the Immune Response to Oral Cholera Vaccine
 

Status: Recruiting

Condition Summary: Cholera; Vibrio Cholerae Infection

 

Last Updated: 14 Dec 2017

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Immunologic Responses to a Live Attenuated Oral Cholera Vaccine
 

Status: Recruiting

Condition Summary: Cholera

 

Last Updated: 17 Jul 2018

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