Cholera

Common Name(s)

Cholera

Cholera is caused by an infection of the intestine by the bacterium Vibrio cholerae. The illness is often mild or without symptoms, but can sometimes be severe, with symptoms typically appearing in 2-3 days. Severe symptoms are characterized by vomiting, profuse diarrhea, and leg cramps. Rapid loss of body fluids in severe cases can lead to dehydration, shock, and death within hours if left untreated. Cholera can be contracted from drinking or eating contaminated food or water. Cholera can spread quickly in areas that have poor treatment of sewage and drinking water, poor sanitation, and poor hygiene. Medical attention should be found immediately for those who think they may have cholera.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholera" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholera" returned 1287 free, full-text research articles on human participants. First 3 results:

Single-Dose Cholera Vaccine in Response to an Outbreak in Zambia.
 

Author(s): Eva Ferreras, Elizabeth Chizema-Kawesha, Alexandre Blake, Orbrie Chewe, John Mwaba, Gideon Zulu, Marc Poncin, Ankur Rakesh, Anne-Laure Page, Savina Stoitsova, Caroline Voute, Florent Uzzeni, Hugues Robert, Micaela Serafini, Belem Matapo, Jose-María Eiros, Marie-Laure Quilici, Lorenzo Pezzoli, Andrew S Azman, Sandra Cohuet, Iza Ciglenecki, Kennedy Malama, Francisco J Luquero

Journal: N. Engl. J. Med.. 2018 02;378(6):577-579.

 

Last Updated: 31 Dec 1969

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Identifying cholera "hotspots" in Uganda: An analysis of cholera surveillance data from 2011 to 2016.
 

Author(s): Godfrey Bwire, Mohammad Ali, David A Sack, Anne Nakinsige, Martha Naigaga, Amanda K Debes, Moise C Ngwa, W Abdullah Brooks, Christopher Garimoi Orach

Journal:

 

Despite advance in science and technology for prevention, detection and treatment of cholera, this infectious disease remains a major public health problem in many countries in sub-Saharan Africa, Uganda inclusive. The aim of this study was to identify cholera hotspots in Uganda to ...

Last Updated: 31 Dec 1969

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The importance of thinking beyond the water-supply in cholera epidemics: A historical urban case-study.
 

Author(s): Matthew D Phelps, Andrew S Azman, Joseph A Lewnard, Marina Antillón, Lone Simonsen, Viggo Andreasen, Peter K M Jensen, Virginia E Pitzer

Journal:

 

Planning interventions to respond to cholera epidemics requires an understanding of the major transmission routes. Interrupting short-cycle (household, foodborne) transmission may require different approaches as compared long-cycle (environmentally-mediated/waterborne) transmission. ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholera" returned 70 free, full-text review articles on human participants. First 3 results:

Protection against cholera from killed whole-cell oral cholera vaccines: a systematic review and meta-analysis.
 

Author(s): Qifang Bi, Eva Ferreras, Lorenzo Pezzoli, Dominique Legros, Louise C Ivers, Kashmira Date, Firdausi Qadri, Laura Digilio, David A Sack, Mohammad Ali, Justin Lessler, Francisco J Luquero, Andrew S Azman,

Journal: Lancet Infect Dis. 2017 Oct;17(10):1080-1088.

 

Killed whole-cell oral cholera vaccines (kOCVs) are becoming a standard cholera control and prevention tool. However, vaccine efficacy and direct effectiveness estimates have varied, with differences in study design, location, follow-up duration, and vaccine composition posing challenges ...

Last Updated: 31 Dec 1969

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Pandemics, pathogenicity and changing molecular epidemiology of cholera in the era of global warming.
 

Author(s): Fazle Rabbi Chowdhury, Zannatun Nur, Nazia Hassan, Lorenz von Seidlein, Susanna Dunachie

Journal:

 

Vibrio cholerae, a Gram-negative, non-spore forming curved rod is found in diverse aquatic ecosystems around the planet. It is classified according to its major surface antigen into around 206 serogroups, of which O1 and O139 cause epidemic cholera. A recent spatial modelling technique ...

Last Updated: 31 Dec 1969

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Oral Cholera Vaccination Delivery Cost in Low- and Middle-Income Countries: An Analysis Based on Systematic Review.
 

Author(s): Vittal Mogasale, Enusa Ramani, Hyeseung Wee, Jerome H Kim

Journal:

 

Use of the oral cholera vaccine (OCV) is a vital short-term strategy to control cholera in endemic areas with poor water and sanitation infrastructure. Identifying, estimating, and categorizing the delivery costs of OCV campaigns are useful in analyzing cost-effectiveness, understanding ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Extended Dose Intervals on the Immune Response to Oral Cholera Vaccine
 

Status: Recruiting

Condition Summary: Cholera; Vibrio Cholerae Infection

 

Last Updated: 14 Dec 2017

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VAXCHORA Pediatric Study
 

Status: Recruiting

Condition Summary: Cholera Vaccination Reaction

 

Last Updated: 7 Feb 2018

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