Cholera

Common Name(s)

Cholera

Cholera is caused by an infection of the intestine by the bacterium Vibrio cholerae. The illness is often mild or without symptoms, but can sometimes be severe, with symptoms typically appearing in 2-3 days. Severe symptoms are characterized by vomiting, profuse diarrhea, and leg cramps. Rapid loss of body fluids in severe cases can lead to dehydration, shock, and death within hours if left untreated. Cholera can be contracted from drinking or eating contaminated food or water. Cholera can spread quickly in areas that have poor treatment of sewage and drinking water, poor sanitation, and poor hygiene. Medical attention should be found immediately for those who think they may have cholera.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholera" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholera" returned 1353 free, full-text research articles on human participants. First 3 results:

An outbreak of cholera in western Kenya, 2015: a case control study.
 

Author(s): Elvis O Oyugi, Waqo Boru, Mark Obonyo, Jane Githuku, Dickens Onyango, Alfred Wandeba, Eunice Omesa, Tabitha Mwangi, Hudson Kigen, Joshua Muiruri, Zeinab Gura

Journal:

 

in February 2015, an outbreak of acute watery diarrhea was reported in two sub counties in western Kenya. e 01 serotype Ogawa was isolated from 26 cases and from water samples collected from a river mainly used by residents of the two sub-counties for domestic purposes. We carried ...

Last Updated: 31 Dec 1969

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Cholera Outbreak in Dadaab Refugee Camp, Kenya - November 2015-June 2016.
 

Author(s): Qabale Golicha, Sharmila Shetty, Orkhan Nasiblov, Abubakar Hussein, Eliud Wainaina, Mark Obonyo, Daniel Macharia, Raymond N Musyoka, Hussein Abdille, Maurice Ope, Rachael Joseph, Willy Kabugi, John Kiogora, Munawwar Said, Waqo Boru, Tura Galgalo, Sara A Lowther, Bonventure Juma, Robert Mugoh, Newton Wamola, Clayton Onyango, Zeinab Gura, Marc-Alain Widdowson, Kevin M DeCock, John W Burton

Journal:

 

Dadaab Refugee camp in Garissa County, Kenya, hosts nearly 340,000 refugees in five subcamps (Dagahaley, Hagadera, Ifo, Ifo2, and Kambioos) (1). On November 18 and 19, 2015, during an ongoing national cholera outbreak (2), two camp residents were evaluated for acute watery diarrhea ...

Last Updated: 31 Dec 1969

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Cholera outbreak in a naïve rural community in Northern Nigeria: the importance of hand washing with soap, September 2010.
 

Author(s): Saheed Gidado, Emmanuel Awosanya, Suleiman Haladu, Halimatu Bolatito Ayanleke, Suleman Idris, Ismaila Mamuda, Abdulaziz Mohammed, Charles Akataobi Michael, Ndadilnasiya Endie Waziri, Patrick Nguku

Journal:

 

Cholera outbreaks in rural communities are associated with high morbidity and mortality. Effective interventions to control these outbreaks require identification of source and risk factors for infection. In September, 2010 we investigated a cholera outbreak in Bashuri, a cholera ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholera" returned 76 free, full-text review articles on human participants. First 3 results:

Changing facades of : An enigma in the epidemiology of cholera.
 

Author(s): N Lekshmi, Iype Joseph, T Ramamurthy, Sabu Thomas

Journal: Indian J. Med. Res.. 2018 Feb;147(2):133-141.

 

Cholera, caused by the Gram-negative bacterium Vibrio cholerae, has ravaged humanity from time immemorial. Although the disease can be treated using antibiotics along with administration of oral rehydration salts and controlled by good sanitation, cholera is known to have produced ...

Last Updated: 31 Dec 1969

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The Cholera Epidemic in Zimbabwe, 2008-2009: A Review and Critique of the Evidence.
 

Author(s): C Nicholas Cuneo, Richard Sollom, Chris Beyrer

Journal: Health Hum Rights. 2017 Dec;19(2):249-264.

 

The 2008-2009 Zimbabwe cholera epidemic resulted in 98,585 reported cases and caused more than 4,000 deaths. In this study, we used a mixed-methods approach that combined primary qualitative data from a 2008 Physicians for Human Rights-led investigation with a systematic review and ...

Last Updated: 31 Dec 1969

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Therapeutic Potential of Cholera Toxin B Subunit for the Treatment of Inflammatory Diseases of the Mucosa.
 

Author(s): Joshua M Royal, Nobuyuki Matoba

Journal:

 

Cholera toxin B subunit (CTB) is a mucosal immunomodulatory protein that induces robust mucosal and systemic antibody responses. This well-known biological activity has been exploited in cholera prevention (as a component of Dukoral vaccine) and vaccine development for decades. On ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Extended Dose Intervals on the Immune Response to Oral Cholera Vaccine
 

Status: Recruiting

Condition Summary: Cholera; Vibrio Cholerae Infection

 

Last Updated: 14 Dec 2017

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Immunologic Responses to a Live Attenuated Oral Cholera Vaccine
 

Status: Recruiting

Condition Summary: Cholera

 

Last Updated: 17 Jul 2018

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CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera
 

Status: Not yet recruiting

Condition Summary: Typhoid and/or Cholera Vaccination

 

Last Updated: 10 Oct 2018

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