Chromosome 13p deletion syndrome, also known as monosomy 13q syndrome, is a rare genetic condition. This condition results from a mutation or error in a person’s DNA or genes. This can cause birth defects such as low birth weight or cleft palate (a hole in the roof of the mouth), as well as low muscle growth, poorly developed oral motor skills, and intellectual disabilities. Although there is currently no cure for chromosome 13p deletion syndrome, there are various resources to help manage the condition and treat birth defects. Doctors seek help from various therapists and community services to provide support and care for families affected by chromosome 13p deletion syndrome.