Chronic fatigue syndrome

Common Name(s)

Chronic fatigue syndrome

Chronic fatigue syndrome is a condition that causes extreme, long-lasting fatigue which can limit the ability to participate in ordinary, daily activities. It generally occurs in young adults between the ages of 20 and 40. The main symptom of this condition is disabling fatigue that does not improve with rest. Other signs and symptoms may include muscle pain; joint pain; concentration and memory problems; headaches; sleep problems; fever; sore throat; and/or tender lymph nodes. The exact cause of chronic fatigue syndrome is not known, but it has been proposed that infectious agents, immune system impairment and/or hormonal system deregulation may be involved. There is no cure for this condition; the goal of treatment is to improve symptoms. Medications may be used to treat pain, sleep disorders and other associated problems.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

Last Updated: 15 Aug 2014

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Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

http://solvecfs.org/

Last Updated: 15 Aug 2014

View Details
Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

http://www.wicfs-me.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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General Resources

SolveCFS BioBank

The SolveCFS BioBank collects and stores a bank of biological samples and clinical information from individuals with CFS and unaffected individuals aged 10 and older.

Updated 6 Dec 2012

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Research1st News

Our free monthly e-newsletter, Research1st News, provides the latest research and policy news, as well as information about upcoming events and media coverage. Visit the archive to read past issues and to sign up to receive upcoming issues by email.

Updated 6 Dec 2012

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SolveCFS: The Chronicle of the CFIDS Association of America

The Association's print publication highlighting how the Association is advancing progress in CFS research and policy and it will share global news of interest to those who are committed to our cause.

Updated 6 Dec 2012

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ME.CFS. Toll free hotline.

Agencies can e mail us to ask for posters to display our hotline number so clients can attain disease information. IMPORTANT TO NOT discard those without computers.

Updated 1 Feb 2013

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Blogs

Research1st

This website is intended to become a one-stop shop for the most current and reliable information about CFS-related research being conducted by top-flight scientists worldwide.

Updated 6 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic fatigue syndrome" returned 723 free, full-text research articles on human participants. First 3 results:

Lower regulatory frequency for postural control in patients with fibromyalgia and chronic fatigue syndrome.
 

Author(s): Omid Rasouli, Ottar Vasseljen, Egil A Fors, Håvard W Lorås, Ann-Katrin Stensdotter

Journal:

 

As many similar symptoms are reported in fibromyalgia (FM) and chronic fatigue syndrome (CFS), underlying defcits may potentially also be similar. Postural disequilibrium reported in both conditions may thus be explained by similar deviations in postural control strategies. 75 females ...

Last Updated: 31 Dec 1969

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Rethinking the treatment of chronic fatigue syndrome-a reanalysis and evaluation of findings from a recent major trial of graded exercise and CBT.
 

Author(s): Carolyn E Wilshire, Tom Kindlon, Robert Courtney, Alem Matthees, David Tuller, Keith Geraghty, Bruce Levin

Journal:

 

The PACE trial was a well-powered randomised trial designed to examine the efficacy of graded exercise therapy (GET) and cognitive behavioural therapy (CBT) for chronic fatigue syndrome. Reports concluded that both treatments were moderately effective, each leading to recovery in ...

Last Updated: 31 Dec 1969

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Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME.
 

Author(s): Carmen Scheibenbogen, Madlen Loebel, Helma Freitag, Anne Krueger, Sandra Bauer, Michaela Antelmann, Wolfram Doehner, Nadja Scherbakov, Harald Heidecke, Petra Reinke, Hans-Dieter Volk, Patricia Grabowski

Journal:

 

Infection-triggered disease onset, chronic immune activation and autonomic dysregulation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) point to an autoimmune disease directed against neurotransmitter receptors. We had observed elevated autoantibodies against ß2 adrenergic ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic fatigue syndrome" returned 72 free, full-text review articles on human participants. First 3 results:

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Evidence for an autoimmune disease.
 

Author(s): Franziska Sotzny, Julià Blanco, Enrica Capelli, Jesús Castro-Marrero, Sophie Steiner, Modra Murovska, Carmen Scheibenbogen,

Journal: Autoimmun Rev. 2018 Jun;17(6):601-609.

 

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a frequent and severe chronic disease drastically impairing life quality. The underlying pathomechanism is incompletely understood yet but there is convincing evidence that in at least a subset of patients ME/CFS has an ...

Last Updated: 31 Dec 1969

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What treatments work for anxiety in children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)? Systematic review.
 

Author(s): Sarah Victoria Ellen Stoll, Esther Crawley, Victoria Richards, Nishita Lal, Amberly Brigden, Maria E Loades

Journal:

 

Anxiety is more prevalent in children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) than in the general population. A systematic review was carried out to identify which treatment methods are most effective for children with CFS and anxiety.

Last Updated: 31 Dec 1969

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Practical management of chronic fatigue syndrome or myalgic encephalomyelitis in childhood.
 

Author(s): Amberly Brigden, Maria Loades, Anna Abbott, Joanne Bond-Kendall, Esther Crawley

Journal: Arch. Dis. Child.. 2017 10;102(10):981-986.

 

Paediatric chronic fatigue syndrome or myalgic encephalomyelitis affects at least 1% of secondary school children in the UK and is very disabling. Treatment is effective but few children get a diagnosis or access treatment. This paper summarises what we currently know about diagnosing ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Nov 2016

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Last Updated: 18 Apr 2018

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Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 5 Oct 2018

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