Chronic kidney disease

Common Name(s)

Chronic kidney disease

Chronic kidney disease (CKD), otherwise known as chronic renal failure, occurs when the kidneys become damaged and lose the ability to properly filter out waste from the blood stream. Conditions such as diabetes, high blood pressure, glomerulonephritis, and polycystic kidney disease have all been linked to the development of CKD.

Symptoms of CKD may include fatigue, poor appetite, anemia (low blood count), nausea, swollen feet, irritated skin, increased need to urinate, shortness of breath, high blood pressure, trouble concentrating, and weakening bones. Early stages often do not show symptoms; therefore, regular checkups are critical for elderly and high risk individuals. A diagnosis can be determined through a blood test, urine test, imaging test, or the removal of sample tissue (biopsy).

While CKD can develop in anyone of any age, adults 65 years or older, and those who are African American, Hispanic, Pacific Islander, and American Indian are most at risk. Other risk factors include smoking, obesity, heart disease, high cholesterol, and having a family history of kidney failure.

There are five stages of CKD, each stage representing a gradual loss of function. End stage kidney failure, the fifth stage, is irreversible and fatal, so prevention and immediate intervention is critical. Depending on the cause, CKD can be treated if the source of the complication can be fixed. If this is not the case, treatment options focus on lessening the symptoms and slowing the progression of the disease. If the condition progresses to the point where the kidneys cannot function on their own, treatments may resort to artificial filtering (dialysis) or a kidney transplant. If you or a loved one has been diagnosed with CKD, talk with your doctor about treatment options. Support groups are also good sources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic kidney disease" for support, advocacy or research.

Alport Syndrome Foundation

Our MISSION is to educate and support patients and their families that have been affected by this genetic kidney disease with the goal of funding research to find more effective treatment protocols and a cure for Alport Syndrome.

Last Updated: 15 Apr 2014

View Details
American Association of Kidney Patients

Dedicated to improving the quality of life for kidney patients through education, advocacy and fostering patient communities.

Last Updated: 5 May 2014

View Details
Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

Last Updated: 14 Mar 2013

View Details
Logo
National Kidney Foundation

The National Kidney Foundation, a major voluntary nonprofit health organization, is dedicated to preventing kidney and urinary tract diseases, improving the health and well-being of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation.

Last Updated: 23 Jun 2015

View Details
Logo
The Cain Foundation for Branchio-oto-renal Syndrome (BOR)

The CAIN FOUNDATION, a voluntary based Charity. Our mission is to represent the interests of many people affected by Branchio-oto-renal Syndrome and to improve their quality of life by providing support and information related to this Syndrome. We seek to educate both Medical Practitioners and the public by promoting Branchio-oto-renal (BOR) Syndrome awareness. Vision to Educate. Mission to Care.

Last Updated: 12 Oct 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic kidney disease" for support, advocacy or research.

Alport Syndrome Foundation

Our MISSION is to educate and support patients and their families that have been affected by this genetic kidney disease with the goal of funding research to find more effective treatment protocols and a cure for Alport Syndrome.

http://www.alportsyndrome.org

Last Updated: 15 Apr 2014

View Details
American Association of Kidney Patients

Dedicated to improving the quality of life for kidney patients through education, advocacy and fostering patient communities.

http://www.aakp.org

Last Updated: 5 May 2014

View Details
Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

http://www.bardetbiedl.org/

Last Updated: 14 Mar 2013

View Details
Logo
National Kidney Foundation

The National Kidney Foundation, a major voluntary nonprofit health organization, is dedicated to preventing kidney and urinary tract diseases, improving the health and well-being of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation.

http://www.kidney.org

Last Updated: 23 Jun 2015

View Details
Logo
The Cain Foundation for Branchio-oto-renal Syndrome (BOR)

The CAIN FOUNDATION, a voluntary based Charity. Our mission is to represent the interests of many people affected by Branchio-oto-renal Syndrome and to improve their quality of life by providing support and information related to this Syndrome. We seek to educate both Medical Practitioners and the public by promoting Branchio-oto-renal (BOR) Syndrome awareness. Vision to Educate. Mission to Care.

http://www.thecainfoundation.com

Last Updated: 12 Oct 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic kidney disease" returned 3822 free, full-text research articles on human participants. First 3 results:

A randomized controlled trial for effectiveness of zolpidem versus acupressure on sleep in hemodialysis patients having chronic kidney disease-associated pruritus.
 

Author(s): Inayat Ur Rehman, David Wu Bin Chia, Raheel Ahmed, Nisar Ahmad Khan, Aziz Ur Rahman, Syed Munib, Learn Han Lee, Kok Gan Chan, Tahir Mehmood Khan

Journal: Medicine (Baltimore). 2018 Aug;97(31):e10764.

 

Pruritus adds to the complications of chronic kidney disease (CKD) patient and a well-recognized complication among the CKD patients. Majority of the patients on hemodialysis experience a generalized pruritus and patients reported being moderately to extremely disturbed by at least ...

Last Updated: 31 Dec 1969

Go To URL
Chronic kidney disease: susceptibility in a representative population-based sample.
 

Author(s): Chislene Pereira Vanelli, Rogério Baumgratz de Paula, Mônica Barros Costa, Marcus Gomes Bastos, Layla de Souza Pires Miranda, Fernando Antonio Basile Colugnati

Journal:

 

Chronic kidney disease has high morbidity and mortality. In order to track the disease, we conducted a population-based study in a medium-sized city in Southeastern Brazil. Based on instrument SCreening for Occult REnal Disease (SCORED), we evaluated 1,016 individuals with mean age ...

Last Updated: 31 Dec 1969

Go To URL
Effects of physician's specialty on regular chronic kidney disease care in predialysis: A population-based cross-sectional study.
 

Author(s): Ming-Yen Lin, Charles Tzu-Chi Lee, Mei-Chuan Kuo, Shang-Jyh Hwang, Hung-Chun Chen, Yi-Wen Chiu

Journal: Medicine (Baltimore). 2018 Jun;97(26):e11317.

 

Late referral in chronic kidney disease (CKD) is associated with irregular care and poor prognosis. How the specialty of healthcare provider affect late referral and irregular CKD care remain unclear.We conducted a population-based cross-sectional study to include incident dialysis ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic kidney disease" returned 933 free, full-text review articles on human participants. First 3 results:

Prevalence of chronic kidney disease-associated pruritus among adult dialysis patients: A meta-analysis of cross-sectional studies.
 

Author(s): Xinmiao Hu, Yan Sang, Mei Yang, Xue Chen, Wenjuan Tang

Journal: Medicine (Baltimore). 2018 May;97(21):e10633.

 

Chronic kidney disease (CKD)-associated pruritus is a common adverse symptom in patients with end-stage renal disease treated by dialysis. Herein, a systematic review and meta-analysis of the prevalence of CKD-associated pruritus among adult dialysis patients was conducted.An electronic ...

Last Updated: 31 Dec 1969

Go To URL
Chronic kidney disease in the global adult HIV-infected population: A systematic review and meta-analysis.
 

Author(s): Udeme E Ekrikpo, Andre P Kengne, Aminu K Bello, Emmanuel E Effa, Jean Jacques Noubiap, Babatunde L Salako, Brian L Rayner, Giuseppe Remuzzi, Ikechi G Okpechi

Journal:

 

The widespread use of antiretroviral therapies (ART) has increased life expectancy in HIV patients, predisposing them to chronic non-communicable diseases including Chronic Kidney Disease (CKD). We performed a systematic review and meta-analysis (PROSPERO registration number CRD42016036246) ...

Last Updated: 31 Dec 1969

Go To URL
Efficacy of febuxostat in hyperuricemic patients with mild-to-moderate chronic kidney disease: a meta-analysis of randomized clinical trials: A PRISMA-compliant article.
 

Author(s): Xiang Xia Zeng, Yunliang Tang, Kaixiang Hu, Xi Zhou, Jiao Wang, Lingyan Zhu, Jianying Liu, Jixiong Xu

Journal: Medicine (Baltimore). 2018 Mar;97(13):e0161.

 

To investigate the efficacy of febuxostat in hyperuricemic patients with chronic kidney disease (CKD), relevant randomized clinical trials (RCTs) were analyzed.

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Clearance of 25-hydroxyvitamin D in Chronic Kidney Disease
 

Status: Recruiting

Condition Summary: Chronic Kidney Disease

 

Last Updated: 22 Jun 2018

Go to URL
Inspiratory Muscle Training in Chronic Kidney Disease
 

Status: Not yet recruiting

Condition Summary: Chronic Kidney Disease

 

Last Updated: 12 Mar 2017

Go to URL
Cardiovascular Comorbidity in Children With Chronic Kidney Disease
 

Status: Recruiting

Condition Summary: Childhood Chronic Kidney Disease

 

Last Updated: 21 Jul 2017

Go to URL