Clear Cell Renal Cell Carcinoma

Common Name(s)

Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma is a cancer of the kidney.  The name "clear cell" refers to the appearance of the cancer cells when viewed with a microscope.   Clear cell renal cell carcinoma occurs when cells in the kidney quickly increase in number, creating a lump (mass).  Though the exact cause of clear cell renal cell carcinoma is unknown, smoking, the excessive use of certain medications, and several genetic predisposition conditions (such as von Hippel Lindau syndrome) may contribute to the development of this type of cancer.  Treatment often begins with surgery to remove as much of the cancer as possible, and may be followed by radiation therapy, chemotherapy, biological therapy, or targeted therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clear Cell Renal Cell Carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clear Cell Renal Cell Carcinoma" returned 692 free, full-text research articles on human participants. First 3 results:

Identification and Validation of Two Novel Prognostic lncRNAs in Kidney Renal Clear Cell Carcinoma.
 

Author(s): Jukun Song, Juxiang Peng, Chen Zhu, Guohui Bai, Yongda Liu, Jianguo Zhu, Jianguo Liu

Journal: Cell. Physiol. Biochem.. 2018 ;48(6):2549-2562.

 

Kidney renal clear cell carcinoma (KIRC) is one of the most fatal malignancies due to late diagnosis and poor treatment. To improve its prognosis, a screening for molecular biomarkers of KIRC is urgently needed. Long non-coding RNAs (lncRNAs) play important roles in tumorigenesis ...

Last Updated: 31 Dec 1969

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Fifteen-gene expression based model predicts the survival of clear cell renal cell carcinoma.
 

Author(s): Ping Li, He Ren, Yan Zhang, Zhaoli Zhou

Journal: Medicine (Baltimore). 2018 Aug;97(33):e11839.

 

Clear-cell renal cell carcinoma (ccRCC) is the major renal cell carcinoma subtype, but its postsurgical prognosis varies among individual patients.We used gene expression, machine learning (random forest variable hunting), and Cox regression analysis to develop a risk score model ...

Last Updated: 31 Dec 1969

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Upregulation of MIAT Regulates LOXL2 Expression by Competitively Binding MiR-29c in Clear Cell Renal Cell Carcinoma.
 

Author(s): Yan Qu, Haibing Xiao, Wen Xiao, Zhiyong Xiong, Wenjun Hu, Yaoying Gao, Zeyuan Ru, Cheng Wang, Lin Bao, Kesan Wang, Hailong Ruan, Zhengshuai Song, Ke Chen, Xiaoping Zhang, Hongmei Yang

Journal: Cell. Physiol. Biochem.. 2018 ;48(3):1075-1087.

 

MIAT is a long noncoding RNA (lncRNA) involved in cell proliferation and the development of tumor. However, the exact effects and molecular mechanisms of MIAT in clear cell renal cell carcinoma (ccRCC) progression are still unknown.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clear Cell Renal Cell Carcinoma" returned 31 free, full-text review articles on human participants. First 3 results:

Multiple metastases of clear-cell renal cell carcinoma to different region of the nasal cavity and paranasal sinus 3 times successively: A case report and literature review.
 

Author(s): Na Zhang, Bing Zhou, Qian Huang, Xiaohong Chen, Shunjiu Cui, Zhenxiao Huang, Yan Sun

Journal: Medicine (Baltimore). 2018 Apr;97(14):e0286.

 

Distant metastasis of clear-cell renal cell carcinoma (ccRCC) to the nasal cavity and paranasal sinus is rare. Endoscopic biopsy used to be performed for diagnosis when it is difficult for complete resection due to intense bleeding during surgery. According to previous literature, ...

Last Updated: 31 Dec 1969

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miRNAs in Prediction of Prognosis in Clear Cell Renal Cell Carcinoma.
 

Author(s): LongJiao Ran, Jian Liang, Xin Deng, JinYu Wu

Journal: Biomed Res Int. 2017 ;2017():4832931.

 

Renal cell carcinoma (RCC) is the most common type of urinary malignancy. Clear cell renal cell carcinoma (ccRCC) is the predominant RCC subtype, accounting for 70-80% of RCC. In recent years, miRNAs have been found to be closely associated with the outcome of the patients with ccRCC. ...

Last Updated: 31 Dec 1969

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Renal clear cell carcinoma metastasis to the breast ten years after nephrectomy: a case report and literature review.
 

Author(s): Yanjun Xu, Rui Hou, Qijie Lu, Yifan Deng, Bin Hu

Journal:

 

Renal cell carcinoma most commonly metastasizes to the lungs, skeleton or liver. Metastatic renal cell carcinoma to the breast is very rare, especially for clear cell carcinoma, and few cases regarding this condition have been reported.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnostic Imaging for Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 26 Sep 2017

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Study of Neoadjuvant Nivolumab in Patients With Non-metastatic Stage II-IV Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 6 Jul 2017

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Nivolumab and Stereotactic Ablative Radiation Therapy (SAbR) for Metastatic Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Metastatic Clear Cell Renal Cell Carcinoma

 

Last Updated: 17 Jul 2018

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