Cryptococcosis

Common Name(s)

Cryptococcosis

Cryptococcosis is a fungal infection caused specifically by the fungus cryptococcus neofromans, which is usually found in soil and bird droppings or less commonly, the fungus cryptococcus gatti, found in sub-tropical regions. An individual usually contracts this infection through the air by breathing in the spores. Cryptococcocsis is most commonly associated with HIV and with people with weakened immune systems such as Hodgkin’s disease, individuals taking high doses of corticosteroid medications or undergoing chemotherapy. However, cryptococcocsis may affect individuals with normal immune systems as well. In some cases, there are no symptoms at all, however because the fungus is typically inhaled, the lungs are most commonly infected. It is more likely to spread beyond the lungs to the brain (and cause meningitis) in individuals with weakened immune systems. Symptoms may include blurred vision, chest pain, fatigue, dry coughs, fever, headache, nausea, sweating, and skin rashes. Other symptoms include mental confusion or unintentional weight loss. Cryptococcosis can be diagnosed through blood tests, CT scans, biopsies, and samples of cerebrospinal fluid (CSF). Cryptococcocis is treated with medications including Amphotericin B, flucytosine, and fluconazole. Cryptococcosis is one of the leading causes of death in individuals living with HIV/AIDS in sub-Saharan Africa. Many efforts are being made to combat this infection. Talk with your doctor about current treatment options if you or a family member has been diagnosed with cryptococcosis

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cryptococcosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cryptococcosis" returned 308 free, full-text research articles on human participants. First 3 results:

Neglected disease, neglected populations: the fight against Cryptococcus and cryptococcosis.
 

Author(s): Marcio L Rodrigues

Journal: Mem. Inst. Oswaldo Cruz. ;113(7):e180111.

 

Last Updated: 31 Dec 1969

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Ulcerative cellulitis of the arm: a case of primary cutaneous cryptococcosis.
 

Author(s): G P Henderson, Sean Dreyer

Journal:

 

Cutaneous cryptococcosis is usually secondary to the hematogenous dissemination of pulmonary or meningeal Cryptococcus neoformans. Primary cutaneous cryptococcosis (PCC) is a rare form of the infection, typically caused by direct inoculation from trauma to the skin [1]. Most cases ...

Last Updated: 31 Dec 1969

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Isolated iliac cryptococcosis in an immunocompetent patient.
 

Author(s): Junjun Sang, Yali Yang, Yibin Fan, Guizhen Wang, Jiu Yi, Wei Fang, Weihua Pan, Jinhua Xu, Wanqing Liao

Journal:

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cryptococcosis" returned 37 free, full-text review articles on human participants. First 3 results:

Diagnostic and therapeutic strategies in cryptococcosis: impact on outcome.
 

Author(s): Timothée Boyer Chammard, Elvis Temfack, Olivier Lortholary, Alexandre Alanio

Journal: Mem. Inst. Oswaldo Cruz. 2018 ;113(7):e180050.

 

Cryptococcosis diagnosis has been recently improved by the use of rapid cryptococcal antigen testing with lateral flow assays, which have proved sensitive and specific. Using "test and treat" screening strategies for cryptococcal disease with these tests has been showed effective ...

Last Updated: 31 Dec 1969

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Variability in innate host immune responses to cryptococcosis.
 

Author(s): Mariam Garelnabi, Robin C May

Journal: Mem. Inst. Oswaldo Cruz. 2018 ;113(7):e180060.

 

Cryptococcosis is an invasive fungal disease caused by Cryptococcus neoformans and the closely related species C. gattii. The severe form of the disease, cryptococcal meningitis (CM), is rapidly fatal without treatment. Although typically a disease of immunocompromised (especially ...

Last Updated: 31 Dec 1969

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The status of cryptococcosis in Latin America.
 

Author(s): Carolina Firacative, Jairo Lizarazo, María Teresa Illnait-Zaragozí, Elizabeth Castañeda,

Journal: Mem. Inst. Oswaldo Cruz. 2018 ;113(7):e170554.

 

Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as occurring worldwide, C. neoformans causes more than 90% of the cases of cryptococcosis, affecting predominantly ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation and Follow-up of Patients With Cryptococcosis
 

Status: Recruiting

Condition Summary: Cryptococcosis

 

Last Updated: 1 Nov 2018

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Vicente Ferrer HIV Cohort Study
 

Status: Recruiting

Condition Summary: HIV; Tuberculosis; Cryptococcosis; Opportunistic Infections; Noncommunicable Diseases

 

Last Updated: 18 Apr 2018

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Treatment With Tamoxifen in Cryptococcal Meningitis
 

Status: Recruiting

Condition Summary: Meningitis Streptococcal; Hiv; Meningitis; Meningoencephalitis

 

Last Updated: 9 Apr 2018

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