Cutaneous T-cell lymphoma

Common Name(s)

Cutaneous T-cell lymphoma

Cutaneous T-cell lymphomas (CTCLs) are a group of disorders characterized by an abnormal accumulation of cancerous T-cells (a type of white blood cells) in the skin resulting in an itchy, red rash that can thicken or form a tumor. CTCLs belong to a larger group of disorders known asnon-Hodgkin's lymphomas. The most common types are mycosis fungoides and SŽzary syndrome. In some cases, cancerous T-cells may spread to the lymph nodes and eventually to other body tissues and organs, potentially resulting in life-threatening complications. The specific signs and symptoms vary from person to person. The exact cause of these conditions is unknown.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous T-cell lymphoma" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

Last Updated: 6 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous T-cell lymphoma" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

http://www.clfoundation.org

Last Updated: 6 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous T-cell lymphoma" returned 460 free, full-text research articles on human participants. First 3 results:

Hydroa vacciniforme-like cutaneous T-cell lymphoma in a child: A case report.
 

Author(s): Jingyi Li, Yiheng Zan, Hongjie Liu, Hanmin Liu, Lina Chen

Journal: Medicine (Baltimore). 2018 04;97(15):e0319.

 

Hydroa vacciniforme (HV)-like T-cell lymphoma is a rare malignancy in childhood associated with Epstein-Barr virus infection.

Last Updated: 31 Dec 1969

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E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T-cell lymphoma: A phase I study.
 

Author(s): Ken Ohmachi, Kiyoshi Ando, Michinori Ogura, Toshiki Uchida, Kensei Tobinai, Dai Maruyama, Masayuki Namiki, Tadashi Nakanishi

Journal: Cancer Sci.. 2018 Mar;109(3):794-802.

 

E7777, a recombinant cytotoxic fusion protein comprising diphtheria toxin fragments A and B and human interleukin-2, shares an amino acid sequence with denileukin diftitox but has improved purity and an increased percentage of active protein monomer species. A phase I study was carried ...

Last Updated: 31 Dec 1969

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Primary cutaneous T-cell lymphoma: experience from the Peruvian National Cancer Institute.
 

Author(s): Rosana Ruiz, Zaida Morante, Raul Mantilla, Luis Mas, Luis Casanova, Henry L Gomez

Journal: An Bras Dermatol. ;92(5):649-654.

 

Primary cutaneous T-cell lymphomas constitute a heterogeneous and rare group of diseases with regional particularities in Latin America.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous T-cell lymphoma" returned 47 free, full-text review articles on human participants. First 3 results:

Total Skin Electron Beam Therapy as Part of Multimodal Treatment Strategies for Primary Cutaneous T-Cell Lymphoma.
 

Author(s): Khaled Elsayad, Katharina H Susek, Hans T Eich

Journal: Oncol Res Treat. 2017 ;40(5):244-252.

 

Total-skin electron beam therapy (TSEBT) is one of most effective treatments that has been used for cutaneous T-cell lymphoma. Low-dose TSEBT regimens (10-12 Gy) appear to be an effective alternative to conventional-dose TSEBT (30-36 Gy), yielding short-term remission of cutaneous ...

Last Updated: 31 Dec 1969

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Proteomic Approaches to Biomarker Discovery in Cutaneous T-Cell Lymphoma.
 

Author(s): Alexandra Ion, Iris Maria Popa, Laura Maria Lucia Papagheorghe, Cristina Lisievici, Mihai Lupu, Vlad Voiculescu, Constantin Caruntu, Daniel Boda

Journal: Dis. Markers. 2016 ;2016():9602472.

 

Cutaneous T-cell lymphoma (CTCL) is the most frequently encountered type of skin lymphoma in humans. CTCL encompasses multiple variants, but the most common types are mycosis fungoides (MF) and Sezary syndrome (SS). While most cases of MF run a mild course over a period of many years, ...

Last Updated: 31 Dec 1969

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Malignant inflammation in cutaneous T-cell lymphoma-a hostile takeover.
 

Author(s): Thorbjørn Krejsgaard, Lise M Lindahl, Nigel P Mongan, Mariusz A Wasik, Ivan V Litvinov, Lars Iversen, Erik Langhoff, Anders Woetmann, Niels Odum

Journal: Semin Immunopathol. 2017 04;39(3):269-282.

 

Cutaneous T-cell lymphomas (CTCL) are characterized by the presence of chronically inflamed skin lesions containing malignant T cells. Early disease presents as limited skin patches or plaques and exhibits an indolent behavior. For many patients, the disease never progresses beyond ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Micro Needle Array-Doxorubicin (MNA-D) in Patients With Cutaneous T-cell Lymphoma (CTCL)
 

Status: Recruiting

Condition Summary: Cutaneous T Cell Lymphoma

 

Last Updated: 16 Feb 2018

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Last Updated: 10 Apr 2018

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Study of IPH4102 in Patients With Relapsed/Refractory Cutaneous T-cell Lymphomas (CTCL)
 

Status: Recruiting

Condition Summary: Cutaneous T-Cell Lymphoma

 

Last Updated: 2 Mar 2017

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