Cutaneous T-cell lymphoma

Common Name(s)

Cutaneous T-cell lymphoma

Cutaneous T-cell lymphomas (CTCLs) are a group of disorders characterized by an abnormal accumulation of cancerous T-cells (a type of white blood cells) in the skin resulting in an itchy, red rash that can thicken or form a tumor. CTCLs belong to a larger group of disorders known asnon-Hodgkin's lymphomas. The most common types are mycosis fungoides and SŽzary syndrome. In some cases, cancerous T-cells may spread to the lymph nodes and eventually to other body tissues and organs, potentially resulting in life-threatening complications. The specific signs and symptoms vary from person to person. The exact cause of these conditions is unknown.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous T-cell lymphoma" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

Last Updated: 6 Jan 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous T-cell lymphoma" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

http://www.clfoundation.org

Last Updated: 6 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous T-cell lymphoma" returned 477 free, full-text research articles on human participants. First 3 results:

[Extranodal Natural Killer/T-Cell Lymphoma, nasal-type with primary cutaneous involvement. A case report].
 

Author(s): Marcos Silva-Feistner, María Jesús Rojas-Lechuga, Elena Ortiz, Montserrat Molgó

Journal: Rev Chil Pediatr. 2018 Apr;89(2):246-250.

 

Extranodal natural killer/T-cell lymphoma (NK/T), nasal type, is an infrequent neoplasm with a high lethality, characterized by bone destruction around the sinus, nasal septum or obstruction of the airway. Also, may be primary skin involvement, airway and other organs. Objecti ve: ...

Last Updated: 31 Dec 1969

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Hydroa vacciniforme-like cutaneous T-cell lymphoma in a child: A case report.
 

Author(s): Jingyi Li, Yiheng Zan, Hongjie Liu, Hanmin Liu, Lina Chen

Journal: Medicine (Baltimore). 2018 04;97(15):e0319.

 

Hydroa vacciniforme (HV)-like T-cell lymphoma is a rare malignancy in childhood associated with Epstein-Barr virus infection.

Last Updated: 31 Dec 1969

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E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T-cell lymphoma: A phase I study.
 

Author(s): Ken Ohmachi, Kiyoshi Ando, Michinori Ogura, Toshiki Uchida, Kensei Tobinai, Dai Maruyama, Masayuki Namiki, Tadashi Nakanishi

Journal: Cancer Sci.. 2018 Mar;109(3):794-802.

 

E7777, a recombinant cytotoxic fusion protein comprising diphtheria toxin fragments A and B and human interleukin-2, shares an amino acid sequence with denileukin diftitox but has improved purity and an increased percentage of active protein monomer species. A phase I study was carried ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous T-cell lymphoma" returned 52 free, full-text review articles on human participants. First 3 results:

Clinical potential of mechlorethamine gel for the topical treatment of mycosis fungoides-type cutaneous T-cell lymphoma: a review on current efficacy and safety data.
 

Author(s): Kendall Liner, Celeste Brown, Laura Y McGirt

Journal:

 

Nitrogen mustard is a chemotherapeutic agent that has a well-documented safety and efficacy profile in the treatment of cutaneous T-cell lymphoma. Development of nitrogen mustard formulations and treatment regimens has been studied extensively over the last 40 years. In the last 5 ...

Last Updated: 31 Dec 1969

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Cutaneous T-cell lymphoma: 2017 update on diagnosis, risk-stratification, and management.
 

Author(s): Ryan A Wilcox

Journal: Am. J. Hematol.. 2017 Oct;92(10):1085-1102.

 

Cutaneous T-cell lymphomas are a heterogenous group of T-cell lymphoproliferative disorders involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS).

Last Updated: 31 Dec 1969

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Cutaneous T-cell Lymphoma.
 

Author(s): Melissa Pulitzer

Journal: Clin. Lab. Med.. 2017 09;37(3):527-546.

 

Cutaneous T-cell lymphomas comprise a heterogeneous group of diseases characterized by monoclonal proliferations of T lymphocytes primarily involving skin, modified skin appendages, and some mucosal sites. This article addresses the basic clinical, histologic, and immunohistochemical ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Micro Needle Array-Doxorubicin (MNA-D) in Patients With Cutaneous T-cell Lymphoma (CTCL)
 

Status: Recruiting

Condition Summary: Cutaneous T Cell Lymphoma

 

Last Updated: 16 Feb 2018

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Last Updated: 12 Oct 2018

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A Trial of E7777 in Persistent and Recurrent Cutaneous T-Cell Lymphoma
 

Status: Recruiting

Condition Summary: Persistent or Recurrent Cutaneous T-Cell Lymphoma

 

Last Updated: 21 Aug 2018

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