Cutaneous lupus erythematosus

Common Name(s)

Cutaneous lupus erythematosus

Cutaneous lupus erythematosus is a form of lupus in which symptoms are limited to the skin and can cause various types of skin rashes. Lupus is an autoimmune disease. Autoimmune diseases occur when your body defense system attack its own healthy cells. Approximately 10% of people with cutaneous lupus erythematosus will develop systemic lupus (please also visit: systemic lupus erythematous) or potentially already have systemic lupus. There are three main categories of cutaneous lupus: chronic cutaneous lupus (CCLE), subacute cutaneous lupus (SCLE) and acute cutaneous lupus (ACLE). The type and location of rashes vary greatly depending on which form a person has. It is important to treat these lesions as they can become progressively worse and turn into skin cancer.

The primary cause of this condition is exposure to sunlight and most often affects women between ages 20-50. Prevention measures include the use of sunscreen or other barriers to prevent exposure to the sun (such as hats) as well as avoiding excess sun exposure during peak hours. Treatment may consist of steroid creams, injections and/or oral antibiotics to treat the skin symptoms. It is important to see a specialist to determine if other systemic symptoms may be present. Management of this condition requires a team of doctors. If you or a family member has been diagnosed with cutaneous lupus erythematosus, talk with your doctor and specialist about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous lupus erythematosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous lupus erythematosus" returned 143 free, full-text research articles on human participants. First 3 results:

Rituximab in the treatment of extensive and refractory subacute cutaneous lupus erythematosus.
 

Author(s): Mariana Álvares Penha, Ricardo da Silva Libório, Hélio Amante Miot

Journal: An Bras Dermatol. 2018 Jun;93(3):467-469.

 

Last Updated: 31 Dec 1969

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Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia.
 

Author(s): Luciana Lima do Nascimento, Milvia Maria Simões E Silva Enokihara, Mônica Ribeiro de Azevedo Vasconcellos

Journal: An Bras Dermatol. 2018 Mar;93(2):274-276.

 

Lupus erythemathosus is a chronic, relapsing disease with acute, subacute, and chronic lesions. Effluvium telogen occurs in the setting of systemic activity of the disease, and cicatricial alopecia results from discoid lesionsin on the scalp. Other types of alopecia, like alopecia ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous lupus erythematosus" returned 16 free, full-text review articles on human participants. First 3 results:

Cutaneous lupus erythematosus: clinico-pathologic correlation.
 

Author(s): Raffaele Filotico, Valentina Mastrandrea

Journal: G Ital Dermatol Venereol. 2018 Apr;153(2):216-229.

 

Cutaneous lupus erythematosus (CLE) is a chronic-relapsing disease. It is defined as a LE localized to the skin without any significant systemic symptoms. Its annual incidence is of 4 cases per 100,000 persons with a prevalence of 73 cases per 100,000 persons. The etiology is unknown ...

Last Updated: 31 Dec 1969

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Prevalence of cutaneous warts in patients with systemic lupus erythematosus: a systematic review.
 

Author(s): Luisa Moreira Silva, Willer Goncalves Dourado Santos, Mittermayer Barretto Santiago

Journal:

 

The aim of this study was to review and evaluate systematically the scientific evidence on the relationship between systemic lupus erythematosus (SLE) and cutaneous warts (CW) caused by human papillomavirus (HPV) infection. With strict inclusion and exclusion criteria, we extensively ...

Last Updated: 31 Dec 1969

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Immunogenetics of cutaneous lupus erythematosus.
 

Author(s): Aimee O Hersh, Lisa M Arkin, Sampath Prahalad

Journal: Curr. Opin. Pediatr.. 2016 08;28(4):470-5.

 

Systemic lupus erythematosus (SLE) is the prototypic autoimmune condition, often affecting multiple organ systems, including the skin. Cutaneous lupus erythematosus (CLE) is distinct from SLE and may be skin limited or associated with systemic disease. Histopathologically, the hallmark ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 10 Oct 2018

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Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus
 

Status: Recruiting

Condition Summary: Cutaneous Lupus Erythematosus

 

Last Updated: 24 Oct 2016

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Study to Evaluate BIIB059 in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus; Active Cutaneous Lupus Erythematosus

 

Last Updated: 28 Sep 2018

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