Cutaneous lupus erythematosus

Common Name(s)

Cutaneous lupus erythematosus

Cutaneous lupus erythematosus is a form of lupus in which symptoms are limited to the skin and can cause various types of skin rashes. Lupus is an autoimmune disease. Autoimmune diseases occur when your body defense system attack its own healthy cells. Approximately 10% of people with cutaneous lupus erythematosus will develop systemic lupus (please also visit: systemic lupus erythematous) or potentially already have systemic lupus. There are three main categories of cutaneous lupus: chronic cutaneous lupus (CCLE), subacute cutaneous lupus (SCLE) and acute cutaneous lupus (ACLE). The type and location of rashes vary greatly depending on which form a person has. It is important to treat these lesions as they can become progressively worse and turn into skin cancer.

The primary cause of this condition is exposure to sunlight and most often affects women between ages 20-50. Prevention measures include the use of sunscreen or other barriers to prevent exposure to the sun (such as hats) as well as avoiding excess sun exposure during peak hours. Treatment may consist of steroid creams, injections and/or oral antibiotics to treat the skin symptoms. It is important to see a specialist to determine if other systemic symptoms may be present. Management of this condition requires a team of doctors. If you or a family member has been diagnosed with cutaneous lupus erythematosus, talk with your doctor and specialist about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous lupus erythematosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous lupus erythematosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous lupus erythematosus" returned 137 free, full-text research articles on human participants. First 3 results:

Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia.
 

Author(s): Luciana Lima do Nascimento, Milvia Maria Simões E Silva Enokihara, Mônica Ribeiro de Azevedo Vasconcellos

Journal: An Bras Dermatol. 2018 Mar;93(2):274-276.

 

Lupus erythemathosus is a chronic, relapsing disease with acute, subacute, and chronic lesions. Effluvium telogen occurs in the setting of systemic activity of the disease, and cicatricial alopecia results from discoid lesionsin on the scalp. Other types of alopecia, like alopecia ...

Last Updated: 31 Dec 1969

Go To URL
Intractable Cutaneous Nontuberculous Mycobacteriosis (Mycobacterium abscessus) during Treatment for Systemic Lupus Erythematosus.
 

Author(s): Dai Kishida, Mitsuto Sato, Chinatsu Kobayashi, Ken-Ichi Ueno, Tomomi Kinoshita, Minori Kodaira, Yasuhiro Shimojima, Wataru Ishii, Atsuhito Ushiki, Shu-Ichi Ikeda

Journal: Intern. Med.. 2017 ;56(10):1253-1257.

 

Mycobacterium abscessus infection tends to occur in patients with an advanced immunocompromised status. We encountered a case of intractable cutaneous M. abscessus infection that developed in a patient with systemic lupus erythematosus (SLE) during maintenance therapy. A 28-year-old ...

Last Updated: 31 Dec 1969

Go To URL
Effects of Hydroxychloroquine in Patients With Cutaneous Lupus Erythematosus: A Multicenter, Double-Blind, Randomized, Parallel-Group Trial.
 

Author(s): N Yokogawa, H Eto, A Tanikawa, T Ikeda, K Yamamoto, T Takahashi, H Mizukami, T Sato, N Yokota, F Furukawa

Journal: Arthritis Rheumatol. 2017 04;69(4):791-799.

 

To assess the efficacy and tolerability of hydroxychloroquine (HCQ) in patients with cutaneous lupus erythematosus (CLE), in a phase III clinical trial conducted in Japan.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous lupus erythematosus" returned 14 free, full-text review articles on human participants. First 3 results:

Prevalence of cutaneous warts in patients with systemic lupus erythematosus: a systematic review.
 

Author(s): Luisa Moreira Silva, Willer Goncalves Dourado Santos, Mittermayer Barretto Santiago

Journal:

 

The aim of this study was to review and evaluate systematically the scientific evidence on the relationship between systemic lupus erythematosus (SLE) and cutaneous warts (CW) caused by human papillomavirus (HPV) infection. With strict inclusion and exclusion criteria, we extensively ...

Last Updated: 31 Dec 1969

Go To URL
Immunogenetics of cutaneous lupus erythematosus.
 

Author(s): Aimee O Hersh, Lisa M Arkin, Sampath Prahalad

Journal: Curr. Opin. Pediatr.. 2016 Aug;28(4):470-5.

 

Systemic lupus erythematosus (SLE) is the prototypic autoimmune condition, often affecting multiple organ systems, including the skin. Cutaneous lupus erythematosus (CLE) is distinct from SLE and may be skin limited or associated with systemic disease. Histopathologically, the hallmark ...

Last Updated: 31 Dec 1969

Go To URL
Cutaneous lupus erythematosus: updates on pathogenesis and associations with systemic lupus.
 

Author(s): Jasmine N Stannard, J Michelle Kahlenberg

Journal: Curr Opin Rheumatol. 2016 09;28(5):453-9.

 

Cutaneous lupus erythematosus (CLE) is a common manifestation among systemic lupus patients. There are no U.S. Food and Drug Administration approved therapies for CLE, and these lesions are frequently disfiguring and refractory to treatment. The present review will cover the recent ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 20 Jun 2018

Go to URL
Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus
 

Status: Recruiting

Condition Summary: Cutaneous Lupus Erythematosus

 

Last Updated: 24 Oct 2016

Go to URL
Study to Evaluate BIIB059 in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus; Active Cutaneous Lupus Erythematosus

 

Last Updated: 14 May 2018

Go to URL