Cyclic Vomiting Syndrome

Common Name(s)

Cyclic Vomiting Syndrome, Cyclic Vomiting

Cyclic vomiting syndrome (CVS) is a condition characterized by recurrent episodes of severe nausea and vomiting. Episodes can last for hours or days. Each episode is usually similar to previous ones. Other symptoms may include physical exhaustion, pale skin, abdominal pain, diarrhea, headache, and/or fever. CVS can begin at any age but is most often diagnosed in children around 5 years of age. The underlying cause of CVS is not known, but children who suffer from migraines are more likely to develop CVS. Treatment aims to control symptoms and may include anti-nausea drugs, sedatives, medications that suppress stomach acid, and/or antidepressants.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cyclic Vomiting Syndrome" for support, advocacy or research.

Cyclic Vomiting Syndrome Association

CVSA will raise awareness, provide education and support to those affected by CVS and advocate for research about nausea and vomiting.

Last Updated: 2 Nov 2012

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cyclic Vomiting Syndrome" for support, advocacy or research.

Cyclic Vomiting Syndrome Association

CVSA will raise awareness, provide education and support to those affected by CVS and advocate for research about nausea and vomiting.

http://www.cvsaonline.org

Last Updated: 2 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cyclic Vomiting Syndrome" returned 23 free, full-text research articles on human participants. First 3 results:

Anxiety and physiological responses to the Trier Social Stress Test for Children in adolescents with cyclic vomiting syndrome.
 

Author(s): Sally E Tarbell, Amanda Millar, Mark Laudenslager, Claire Palmer, John E Fortunato

Journal: Auton Neurosci. 2017 01;202():79-85.

 

This study compared anxiety and physiological responses during the Trier Social Stress Test for Children (TSST-C) in adolescents. 38 subjects (26 females) were enrolled: 11 cyclic vomiting syndrome (CVS), 11 anxiety, and 16 controls. Salivary cortisol, α-amylase and heart rate variability ...

Last Updated: 31 Dec 1969

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Cerebral vasospasm and wernicke encephalopathy secondary to adult cyclic vomiting syndrome: the role of magnesium.
 

Author(s): Álvaro Sánchez-Larsen, Tomás Segura, Susana García-Muñozguren, Javier Peinado-Ródenas, Joaquín Zamarro, Francisco Hernández-Fernández

Journal:

 

Magnesium has a regulatory role in the excitability of cell membranes, and is also a cofactor in the phosphorylation of thiamine. Hypomagnesemia has been associated with coronary vasospasm, but its role in cerebrovascular pathology is controversial, and cerebral vasospasm exclusively ...

Last Updated: 31 Dec 1969

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Endocannabinoid-related lipids are increased during an episode of cyclic vomiting syndrome.
 

Author(s): T Venkatesan, Y Zadvornova, H Raff, C J Hillard

Journal: Neurogastroenterol. Motil.. 2016 Sep;28(9):1409-18.

 

The endocannabinoid system and the hypothalamic-pituitary-adrenal axis are important neuromodulators of nausea and vomiting. This led us to hypothesize that patients with cyclic vomiting syndrome (CVS) have lower serum endocannabinoids (eCBs) and higher salivary cortisol and alpha amylase.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cyclic Vomiting Syndrome" returned 4 free, full-text review articles on human participants. First 3 results:

Cyclic Vomiting Syndrome: An Update Illustrated by a Case Report.
 

Author(s): Ingeborg P M Hermus, Stacey J B Willems, Aimée C C F Bogman, Paddy K C Janssen, Leonie Brabers, Jan N M Schieveld

Journal:

 

This article presents an update on cyclic vomiting syndrome, a potentially exhausting disorder that can occur in children, adolescents, and adults and and has a huge impact on the quality of life. A structured literature search was conducted to explore the current knowledge about ...

Last Updated: 31 Dec 1969

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Acute episode of cyclic vomiting syndrome preceded by arterial hypertension – Case presentation and review.
 

Author(s): K Keller, A Desuki, L Hobohm, T Münzel, M A Ostad

Journal: Neth J Med. 2015 Oct;73(8):379-82.

 

Cyclic vomiting syndrome (CVS) is a functional disorder with recurrent episodes of vomiting. Between these episodes patients recover to well-being. Lack of awareness often leads to a delay in making the diagnosis. The diagnosis is based on a typical medical history and exclusion of ...

Last Updated: 31 Dec 1969

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Review article: cyclic vomiting syndrome in adults--rediscovering and redefining an old entity.
 

Author(s): R A Hejazi, R W McCallum

Journal: Aliment. Pharmacol. Ther.. 2011 Aug;34(3):263-73.

 

Cyclic vomiting syndrome is a disorder characterised by recurrent episodes of severe nausea and vomiting separated by symptom-free periods.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Auricular Neurostimulation for Cyclic Vomiting Syndrome
 

Status: Recruiting

Condition Summary: Cyclic Vomiting Syndrome; Abdominal Migraine

 

Last Updated: 14 Feb 2018

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Topical Capsaicin for Cyclical Vomiting
 

Status: Recruiting

Condition Summary: Cyclical Vomiting

 

Last Updated: 20 Dec 2017

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Genetic Analysis of Children With Cyclic Vomiting Syndrome (CVS) and Migraines
 

Status: Recruiting

Condition Summary: Vomiting; Migraines

 

Last Updated: 22 Mar 2018

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