Cytokine Deficiency

Common Name(s)

Cytokine Deficiency

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cytokine Deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cytokine Deficiency" returned 24 free, full-text research articles on human participants. First 3 results:

Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice.
 

Author(s): Lisa K Wagner, Kate E Gilling, Eileen Schormann, Peter M Kloetzel, Frank L Heppner, Elke Kr├╝ger, Stefan Prokop

Journal:

 

The immunoproteasome (iP) represents a specialized type of proteasomes, which plays an important role in the clearance of oxidant-damaged proteins under inflammatory and pathological conditions determining the outcome of various diseases. In Alzheimer's disease (AD)-like APPPS1 mice ...

Last Updated: 31 Dec 1969

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STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.
 

Author(s): Shohei Koyama, Esra A Akbay, Yvonne Y Li, Amir R Aref, Ferdinandos Skoulidis, Grit S Herter-Sprie, Kevin A Buczkowski, Yan Liu, Mark M Awad, Warren L Denning, Lixia Diao, Jing Wang, Edwin R Parra-Cuentas, Ignacio I Wistuba, Margaret Soucheray, Tran Thai, Hajime Asahina, Shunsuke Kitajima, Abigail Altabef, Jillian D Cavanaugh, Kevin Rhee, Peng Gao, Haikuo Zhang, Peter E Fecci, Takeshi Shimamura, Matthew D Hellmann, John V Heymach, F Stephen Hodi, Gordon J Freeman, David A Barbie, Glenn Dranoff, Peter S Hammerman, Kwok-Kin Wong

Journal: Cancer Res.. 2016 Mar;76(5):999-1008.

 

STK11/LKB1 is among the most commonly inactivated tumor suppressors in non-small cell lung cancer (NSCLC), especially in tumors harboring KRAS mutations. Many oncogenes promote immune escape, undermining the effectiveness of immunotherapies, but it is unclear whether the inactivation ...

Last Updated: 31 Dec 1969

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Cytokine secretion and NK cell activity in human ADAM17 deficiency.
 

Author(s): Pinchas Tsukerman, Eli M Eisenstein, Maor Chavkin, Dominik Schmiedel, Eitan Wong, Marion Werner, Barak Yaacov, Diana Averbuch, Vered Molho-Pessach, Polina Stepensky, Noa Kaynan, Yotam Bar-On, Einat Seidel, Rachel Yamin, Irit Sagi, Orly Elpeleg, Ofer Mandelboim

Journal: Oncotarget. 2015 Dec;6(42):44151-60.

 

Genetic deficiencies provide insights into gene function in humans. Here we describe a patient with a very rare genetic deficiency of ADAM17. We show that the patient's PBMCs had impaired cytokine secretion in response to LPS stimulation, correlating with the clinical picture of severe ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cytokine Deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Vitamin D Supplementation in Patients With Heart Failure and Vitamin D Deficiency
 

Status: Recruiting

Condition Summary: Heart Failure; Vitamin D Deficiency

 

Last Updated: 12 Sep 2017

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Last Updated: 20 Jun 2018

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Genetic Basis of Primary Immunodeficiencies
 

Status: Recruiting

Condition Summary: Immunologic Deficiency Syndrome

 

Last Updated: 27 Mar 2018

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