Diffuse esophageal spasm

Common Name(s)

Diffuse esophageal spasm, DES

Diffuse esophageal spasm (DES) is a condition characterized by uncoordinated contractions of the esophagus during swallowing. The esophagus is the tube that contracts or squeezes to help move food from the mouth to the stomach. These spasms do not properly propel food into the stomach and can cause chest pain, regurgitation, heartburn, the feeling that something is stuck, or difficulty swallowing (dysphagia).

Though the exact cause of DES is unknown, there are several suspected causes. One is by atypical brain signals to the esophagus which triggers a spasm or that there may be an underlying condition such as reflux causing it. Another cause may be a problem with the muscles in the lower portion of the esophagus (achalasia). It is thought that anxiety or panic attacks may also be a culprit in some. Treatment includes treating the underlying medical condition if there is one determined. Other options include dietary changes or medications to reduce the level of acid in the stomach. It is also thought that that DES can be triggered by very hot or cold beverages. Therefore, avoiding these beverages may alleviate symptoms. Diagnosis is made by documenting a history of spasms and possible triggers along with specific testing such as a barium swallow. If you or a loved one has been diagnosed with diffuse esophageal spasm, talk to your doctor to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diffuse esophageal spasm" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diffuse esophageal spasm" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diffuse esophageal spasm" returned 4 free, full-text research articles on human participants. First 3 results:

Rare radiological pattern of diffuse esophageal spasm.
 

Author(s): Demis N Lipe, Nathan Borden

Journal: West J Emerg Med. 2015 May;16(3):426-7.

 

Last Updated: 19 May 2015

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Symptomatic improvement of diffuse esophageal spasm after botulinum toxin injection.
 

Author(s): Jae Pil Han, Su Jin Hong, Hoon Il Kim, Jin Myung Byun, Hwa Jong Kim, Bong Min Ko, Joon Seong Lee, Moon Sung Lee

Journal: Korean J Gastroenterol. 2012 Aug;60(2):109-12.

 

Diffuse esophageal spasm, an uncommon esophageal motility disorder, has recently been defined using high-resolution manometry. Patients with distal esophageal spasm usually complain of chest pain or dysphagia. The etiology and pathophysiology of this disorder are poorly known, and ...

Last Updated: 28 Aug 2012

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Physiologic evaluation of esophageal function in patients with achalasia and diffuse esophageal spasm.
 

Author(s): A G Little, D B Skinner, W H Chen, A Evander, M K Ferguson, M Krzystek

Journal: Ann. Surg.. 1986 May;203(5):500-4.

 

To evaluate function of the normal and pathologic esophageal body under more physiologic conditions than those utilized for traditional laboratory testing, manometry was performed before and during eating using a catheter assembly containing three peripheral transducers. Studies were ...

Last Updated: 30 May 1986

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diffuse esophageal spasm" returned 1 free, full-text review articles on human participants. First 3 results:

Diffuse esophageal spasm: transforming into achalasia.
 

Author(s): S W Shah, A A Khan, A Alam, A K Butt, F Shafqat

Journal: J Pak Med Assoc. 1998 Feb;48(2):58-60.

 

Last Updated: 30 Jun 1998

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Clinical Trial Information This information is provided by ClinicalTrials.gov

NEQOL Survey Spanish Validation in a Hispanic Clinic Based Population
 

Status: Recruiting

Condition Summary: Gastroesophageal Reflux Disease and Esophageal Motility Disorders

 

Last Updated: 8 Nov 2016

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Different Surgical Procedures of Peroral Endoscopic Myotomy(POEM) for Esophageal Achalasia
 

Status: Recruiting

Condition Summary: Esophageal Achalasia; Esophageal Motility Disorders

 

Last Updated: 11 May 2017

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Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders
 

Status: Not yet recruiting

Condition Summary: Esophageal Achalasia; Esophageal Spasm, Diffuse; Esophageal Motility Disorders

 

Last Updated: 29 Aug 2016

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