Dandy-Walker syndrome

Common Name(s)

Dandy-Walker syndrome, Dandy-Walker complex

Dandy-Walker complex is a congenital brain malformation involving the cerebellum (an area at the back of the brain that controls movement) and the fluid-filled spaces around it. This condition is characterized by an enlargement of the fourth ventricle (a small channel that allows fluid to flow freely between the upper and lower areas of the brain and spinal cord), a partial or complete absence of the cerebellar vermis (the area between the two cerebellar hemispheres), and cyst formation near the internal base of the skull. This condition may present with an increase in fluid and pressure around the skull (hydrocephalus). It may also be associated with developmental delay, or malformations of the heart, face, limbs, fingers, or toes. The term "Dandy-Walker complex" represents a spectrum of abnormalities that includes Dandy-Walker variant, Dandy-Walker malformation, and mega cisterna magna.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dandy-Walker syndrome" for support, advocacy or research.

Dandy-Walker Alliance, Inc.

The Dandy-Walker Alliance, Inc. is a non-profit corporation providing support and outreach to families, producing educational publications, hosting awareness events and programs, and funding research for the most common malformation of the hindbrain region, Dandy-Walker Syndrome. We support all efforts to determine the causes of, find the cure for and to ameliorate the effects of Dandy-Walker Syndrome.

Last Updated: 17 Jun 2016

View Details
Logo
Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

Last Updated: 22 Apr 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dandy-Walker syndrome" for support, advocacy or research.

Dandy-Walker Alliance, Inc.

The Dandy-Walker Alliance, Inc. is a non-profit corporation providing support and outreach to families, producing educational publications, hosting awareness events and programs, and funding research for the most common malformation of the hindbrain region, Dandy-Walker Syndrome. We support all efforts to determine the causes of, find the cure for and to ameliorate the effects of Dandy-Walker Syndrome.

http://www.dandy-walker.org

Last Updated: 17 Jun 2016

View Details
Logo
Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

http://www.pediatricbrainfoundation.org

Last Updated: 22 Apr 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dandy-Walker syndrome" returned 21 free, full-text research articles on human participants. First 3 results:

Dandy-Walker syndrome with duplex kidney abnormalities in trisomy 18 - A rare case report.
 

Author(s): Tun-Jun Wang, Yi-Ying Li, Wan-Ju Wu, Chi-Kang Lin, Chun-Kai Wang, Chen-Yu Wang, Kwei-Shuai Hwang, Her-Young Su

Journal: Taiwan J Obstet Gynecol. 2017 Oct;56(5):697-699.

 

Trisomy 18 is one of the major numerical chromosomal disorders. The incidence of trisomy 18 is approximately one in 6000 live births. Dandy-Walker malformation (DWM) is the most common congenital malformation of the cerebellum, with an incidence of about one in 5000 live births. The ...

Last Updated: 31 Dec 1969

Go To URL
Dandy-Walker Malformation and Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episode Syndrome: Is There a Causal or Coincidental Association?
 

Author(s): Pu-Gang Li, Ya-Nan Tang, Shuang-Shuang Zheng, Wei-Kang Chen, Li-Ping Lu

Journal: Chin. Med. J.. 2016 Mar;129(5):620-1.

 

Last Updated: 31 Dec 1969

Go To URL
Asymptomatic Dandy-Walker syndrome in an adult.
 

Author(s): Hatim Belfquih, Brahim Elmostarchid

Journal:

 

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dandy-Walker syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

The Most Common Comorbidities in Dandy-Walker Syndrome Patients: A Systematic Review of Case Reports.
 

Author(s): Emelina Stambolliu, Myrsini Ioakeim-Ioannidou, Kimonas Kontokostas, Maria Dakoutrou, Antonis A Kousoulis

Journal: J. Child Neurol.. 2017 Sep;32(10):886-902.

 

Dandy-Walker syndrome (DWS) is a rare neurologic multi-entity malformation. This review aimed at reporting its main nonneurologic comorbidities.

Last Updated: 31 Dec 1969

Go To URL
Successful treatment of Dandy-Walker syndrome by endoscopic third ventriculostomy in a 6-month-old girl with progressive hydrocephalus: a case report and literature review.
 

Author(s): Chih-Fen Hu, Hueng-Chuen Fan, Cheng-Fu Chang, Chih-Chien Wang, Shyi-Jou Chen

Journal: Pediatr Neonatol. 2011 Feb;52(1):42-5.

 

Dandy-Walker syndrome (DWS) is a congenital brain malformation involving the cerebellum and fourth ventricle. We report a 6-month-old girl with DWS presenting an initially normal ventricular system and mild cyst-like lesion over the posterior fossa as assessed by postnatal brain sonography. ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetic Analysis of PHACE Syndrome (Hemangioma With Other Congenital Anomalies)
 

Status: Recruiting

Condition Summary: PHACE Syndrome

 

Last Updated: 1 Feb 2018

Go to URL
Brain Development Research Program
 

Status: Recruiting

Condition Summary: Brain Disorders; Aicardi Syndrome

 

Last Updated: 9 Jan 2017

Go to URL