Dementia

Common Name(s)

Dementia

Dementia is not a disease, but is a term that describes a loss of cognitive functioning, such as thinking, remembering, and reasoning, and behavioral abilities to the extent that it interferes with a person’s daily life. Many conditions cause dementia and symptoms may vary depending on the cause. However, common symptoms include memory loss, difficulty communicating, difficulty planning and organizing, difficulty with motor functions, personality changes, disorientation, paranoia, inability to reason and inappropriate behavior. A physician can diagnose dementias after taking into account medical history and performance on a number of tests such as cognitive and neuropsychological tests, brain scans, blood tests, and psychiatric evaluation. Most types of dementia cannot be cured, however medication and occupational therapy can be used to manage symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia" for support, advocacy or research.

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Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

Last Updated: 8 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia" for support, advocacy or research.

Logo
Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

http://www.nia.nih.gov/alzheimers

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

http://www.theaftd.org

Last Updated: 8 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dementia" returned 5313 free, full-text research articles on human participants. First 3 results:

A novel network analysis approach reveals DNA damage, oxidative stress and calcium/cAMP homeostasis-associated biomarkers in frontotemporal dementia.
 

Author(s): Fernando Palluzzi, Raffaele Ferrari, Francesca Graziano, Valeria Novelli, Giacomina Rossi, Daniela Galimberti, Innocenzo Rainero, Luisa Benussi, Benedetta Nacmias, Amalia C Bruni, Daniele Cusi, Erika Salvi, Barbara Borroni, Mario Grassi

Journal:

 

Frontotemporal Dementia (FTD) is the form of neurodegenerative dementia with the highest prevalence after Alzheimer's disease, equally distributed in men and women. It includes several variants, generally characterized by behavioural instability and language impairments. Although ...

Last Updated: 11 Oct 2017

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Thrombolysis in acute ischemic stroke in patients with dementia: A Swedish registry study.
 

Author(s): Eva Zupanic, Mia von Euler, Ingemar Kåreholt, Beatriz Contreras Escamez, Johan Fastbom, Bo Norrving, Dorota Religa, Milica G Kramberger, Bengt Winblad, Kristina Johnell, Maria Eriksdotter, Sara Garcia-Ptacek

Journal: Neurology. 2017 Oct;89(18):1860-1868.

 

To compare access to intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) and its outcomes in patients with and without dementia.

Last Updated: 7 Oct 2017

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Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease.
 

Author(s): Eva A Zeestraten, Andrew J Lawrence, Christian Lambert, Philip Benjamin, Rebecca L Brookes, Andrew D Mackinnon, Robin G Morris, Thomas R Barrick, Hugh S Markus

Journal: Neurology. 2017 Oct;89(18):1869-1876.

 

To determine whether MRI markers, including diffusion tensor imaging (DTI), can predict cognitive decline and dementia in patients with cerebral small vessel disease (SVD).

Last Updated: 5 Oct 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dementia" returned 894 free, full-text review articles on human participants. First 3 results:

What do Cochrane systematic reviews say about non-pharmacological interventions for treating cognitive decline and dementia?
 

Author(s): Vitória Carvalho Vilela, Rafael Leite Pacheco, Carolina Oliveira Cruz Latorraca, Daniela Vianna Pachito, Rachel Riera

Journal: Sao Paulo Med J. ;135(3):309-320.

 

Dementia is a highly prevalent condition worldwide. Its chronic and progressive presentation has an impact on physical and psychosocial characteristics and on public healthcare. Our aim was to summarize evidence from Cochrane reviews on non-pharmacological treatments for cognitive ...

Last Updated: 26 Jul 2017

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Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia.
 

Author(s): Deepti Lall, Robert H Baloh

Journal: J. Clin. Invest.. 2017 Sep;127(9):3250-3258.

 

Amyotrophic lateral sclerosis (ALS) is a degenerative disorder that is characterized by loss of motor neurons and shows clinical, pathological, and genetic overlap with frontotemporal dementia (FTD). Activated microglia are a universal feature of ALS/FTD pathology; however, their ...

Last Updated: 24 Jul 2017

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Core outcome measures for interventions to prevent or slow the progress of dementia for people living with mild to moderate dementia: Systematic review and consensus recommendations.
 

Author(s): Lucy Webster, Derek Groskreutz, Anna Grinbergs-Saull, Rob Howard, John T O'Brien, Gail Mountain, Sube Banerjee, Bob Woods, Robert Perneczky, Louise Lafortune, Charlotte Roberts, Jenny McCleery, James Pickett, Frances Bunn, David Challis, Georgina Charlesworth, Katie Featherstone, Chris Fox, Claire Goodman, Roy Jones, Sarah Lamb, Esme Moniz-Cook, Justine Schneider, Sasha Shepperd, Claire Surr, Jo Thompson-Coon, Clive Ballard, Carol Brayne, Alistair Burns, Linda Clare, Peter Garrard, Patrick Kehoe, Peter Passmore, Clive Holmes, Ian Maidment, Louise Robinson, Gill Livingston

Journal:

 

There are no disease-modifying treatments for dementia. There is also no consensus on disease modifying outcomes. We aimed to produce the first evidence-based consensus on core outcome measures for trials of disease modification in mild-to-moderate dementia.

Last Updated: 29 Jun 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hand Grasping Techniques on Eliciting the Grasp Reflex in Patients With Dementia
 

Status: Recruiting

Condition Summary: Dementia

 

Last Updated: 4 Oct 2016

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A Trial of the C-TraC Intervention for Dementia Patients
 

Status: Recruiting

Condition Summary: Dementia

 

Last Updated: 2 May 2017

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