Dengue

Common Name(s)

Dengue, Dengue virus, susceptibility to

Dengue is a virus that is carried by mosquitos and affects over 100 million people worldwide each year. The virus is passed to humans through mosquito bites. Those who inhabit or visit tropical or sub-tropical regions, particularly in urban or suburban areas, are most at risk for infection. Symptoms of Dengue include a high fever, intense headache or aching behind the eyes, joint pain, easy bruising, gum or nose bleeds, bone and muscle pain, swollen glands, and a rash. Symptoms usually appear 4-10 days after infection and last for 2-7 days.

There are four types of dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. Once an individual has recovered from one of these types, that individual will not develop symptoms from that same type again. When an individual is infected by a different type, however, there is a risk for severe dengue. Symptoms of severe dengue include vomiting (sometimes bloody), tiredness, severe stomach pain, fast breathing, restlessness, and bleeding gums. These symptoms occur after the high fever of dengue has dropped. Severe dengue requires immediate treatment, as it can cause the liquid part of the blood (plasma) to leak from small blood vessels (capillaries). This condition leads to severe loss of blood volume (shock) and can be life-threatening. Other complications may include internal bleeding, difficulty breathing, and accumulation of fluid in the body.

Severe dengue is treated by fluid replacement therapy. Dengue prevention methods focus on avoiding mosquitos, such as by getting rid of stagnant water in containers where mosquitos lay eggs and using bed nets during the night and mosquito repellant when outdoors. If you have been diagnosed with dengue, talk to your doctor about current treatment options. In addition, consult a medical professional for advice before traveling to areas where there is a potential to be infected by the dengue virus.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dengue" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dengue" returned 4169 free, full-text research articles on human participants. First 3 results:

Immunogenicity of the CYD tetravalent dengue vaccine using an accelerated schedule: randomised phase II study in US adults.
 

Author(s): Judith Kirstein, William Douglas, Manoj Thakur, Mark Boaz, Thomas Papa, Anna Skipetrova, Eric Plennevaux

Journal:

 

The live attenuated tetravalent dengue vaccine (CYD-TDV) is licensed using a 0-, 6- and 12-month schedule in dengue-endemic areas. An effective shorter schedule may provide more rapid, optimal protection of targeted populations during vaccine campaigns in dengue-endemic countries. ...

Last Updated: 31 Dec 1969

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Thrombotic thrombocytopenic purpura associated with dengue and chikungunya virus coinfection: case report during an epidemic period.
 

Author(s): Maria Luiza Almeida Bastos, Ruth Maria Oliveira de Araújo, Deivide de Sousa Oliveira, Ana Nery Melo Cavalcante, Geraldo Bezerra da Silva Junior

Journal: Rev. Inst. Med. Trop. Sao Paulo. 2018 ;60():e48.

 

The present report shows the occurrence of thrombotic thrombocytopenic purpura (TTP) associated with acute dengue and chikungunya virus coinfection, manifesting as a severe disease with high mortality potential. The patient was a 28 year-old man with clinical and epidemiological diagnosis ...

Last Updated: 31 Dec 1969

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Potential of Aedes aegypti populations in Madeira Island to transmit dengue and chikungunya viruses.
 

Author(s): Gonçalo Seixas, Henri Jupille, Pei-Shi Yen, Bela Viveiros, Anna-Bella Failloux, Carla Alexandra Sousa

Journal:

 

Aedes spp. mosquitoes mainly transmit the arboviruses dengue virus (DENV) and chikungunya virus (CHIKV) in urban areas, causing a severe public health problem. In 2012-2013, a major dengue outbreak occurred on Madeira Island where the mosquito Aedes aegypti was the only vector. Up ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dengue" returned 332 free, full-text review articles on human participants. First 3 results:

Ten-years trend of dengue research in Indonesia and South-east Asian countries: a bibliometric analysis.
 

Author(s): Ahmad Watsiq Maula, Anis Fuad, Adi Utarini

Journal: Glob Health Action. 2018 ;11(1):1504398.

 

Dengue fever is a mosquito-borne viral disease with high incidence in over 128 countries. WHO estimates 500,000 people with severe dengue are hospitalized annually and 2.5% of those affected die. Indonesia is a hyperendemic country for dengue with an increasing number of cases in ...

Last Updated: 31 Dec 1969

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Dengue Cerebellitis: A Case Report and Literature Review.
 

Author(s): Ching Soong Khoo

Journal:

 

BACKGROUND Dengue-associated neurological manifestations have recently been on the rise. Cerebellar syndrome complicating dengue fever has rarely been reported in the literature. We present a case report of dengue-associated cerebellar syndrome and performed a literature review to ...

Last Updated: 31 Dec 1969

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Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate.
 

Author(s): Hong-Ru Chen, Yen-Chung Lai, Trai-Ming Yeh

Journal:

 

Dengue virus (DENV) infection is the most common mosquito-transmitted viral infection. DENV infection can cause mild dengue fever or severe dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). Hemorrhage and vascular leakage are two characteristic symptoms of DHF/DSS. However, ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pilot Study to Detect DENGUE Virus in Sperm
 

Status: Not yet recruiting

Condition Summary: Dengue

 

Last Updated: 22 Aug 2018

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Last Updated: 14 Aug 2018

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The Use of Biomarkers in Predicting Dengue Outcome
 

Status: Recruiting

Condition Summary: Dengue

 

Last Updated: 24 Oct 2016

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