Dengue

Common Name(s)

Dengue, Dengue virus, susceptibility to

Dengue is a virus that is carried by mosquitos and affects over 100 million people worldwide each year. The virus is passed to humans through mosquito bites. Those who inhabit or visit tropical or sub-tropical regions, particularly in urban or suburban areas, are most at risk for infection. Symptoms of Dengue include a high fever, intense headache or aching behind the eyes, joint pain, easy bruising, gum or nose bleeds, bone and muscle pain, swollen glands, and a rash. Symptoms usually appear 4-10 days after infection and last for 2-7 days.

There are four types of dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. Once an individual has recovered from one of these types, that individual will not develop symptoms from that same type again. When an individual is infected by a different type, however, there is a risk for severe dengue. Symptoms of severe dengue include vomiting (sometimes bloody), tiredness, severe stomach pain, fast breathing, restlessness, and bleeding gums. These symptoms occur after the high fever of dengue has dropped. Severe dengue requires immediate treatment, as it can cause the liquid part of the blood (plasma) to leak from small blood vessels (capillaries). This condition leads to severe loss of blood volume (shock) and can be life-threatening. Other complications may include internal bleeding, difficulty breathing, and accumulation of fluid in the body.

Severe dengue is treated by fluid replacement therapy. Dengue prevention methods focus on avoiding mosquitos, such as by getting rid of stagnant water in containers where mosquitos lay eggs and using bed nets during the night and mosquito repellant when outdoors. If you have been diagnosed with dengue, talk to your doctor about current treatment options. In addition, consult a medical professional for advice before traveling to areas where there is a potential to be infected by the dengue virus.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dengue" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dengue" returned 4098 free, full-text research articles on human participants. First 3 results:

Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report.
 

Author(s): Rakitha Higgoda, Dilshan Perera, Kanapathipillai Thirumavalavan

Journal:

 

Dengue infection is an endemic illness in the tropics and it is associated with a wide variety of post infectious complications. With the increasing prevalence of dengue infection in endemic regions, post-infectious neurological complications following dengue infection are now been ...

Last Updated: 31 Dec 1969

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First documented evidence of dengue and malaria co-infection in children attending two health centers in Yaoundé, Cameroon.
 

Author(s): Gwladys Chavely Monamele, Maurice Demanou

Journal:

 

To date, only a few cases of malaria and dengue co-infections have been reported around the world. We describe for the first time in Cameroon, concurrent infections among children (2 to 10 years) in two health centers of Yaoundé. The two dengue strains isolated in Cameroon clustered ...

Last Updated: 31 Dec 1969

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Dengue fever-associated necrotizing scleritis: A case report with long-term follow-up.
 

Author(s): Koju Kamoi, Manabu Mochizuki, Kyoko Ohno-Matsui

Journal: Medicine (Baltimore). 2018 Aug;97(32):e11875.

 

Dengue fever is a notable emerging infectious disease that is now seen worldwide, with an estimated incidence of approximately 390 million cases per year. Although ocular complications are uncommon among dengue fever-infected patients, caution is needed to prevent vision loss. Here ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dengue" returned 323 free, full-text review articles on human participants. First 3 results:

[Plasma viraemia as a factor associated to severity in dengue virus infection: systematic review of literature].
 

Author(s): Sergio Alejandro Gómez-Ochoa

Journal: Rev Chilena Infectol. 2018 04;35(2):176-183.

 

Plasma viremia is a factor whose role in the severity of dengue virus infection has been widely discussed in recent years, with divergent results found in the multiple contexts evaluated.

Last Updated: 31 Dec 1969

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The Autoimmune Mechanism in Dengue Hemorrhagic Fever.
 

Author(s): Soroy Lardo, Marsetyawan Hne Soesatyo, Juffrie Juffrie, Sitti Rahmah Umniyati

Journal: Acta Med Indones. 2018 Jan;50(1):70-79.

 

The immune response of dengue fever/dengue hemorrhagic fever is a series of immunopathogenesis processes starting from viral infection to the target on monocytes and macrophages. It may consequently cause a cascade of viremia in the circulation that stimulates the afferent, efferent, ...

Last Updated: 31 Dec 1969

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Dengue Virus and Its Inhibitors: A Brief Review.
 

Author(s): Yu-Shi Tian, Yi Zhou, Tatsuya Takagi, Masanori Kameoka, Norihito Kawashita

Journal: Chem. Pharm. Bull.. 2018 ;66(3):191-206.

 

The global occurrence of viral infectious diseases poses a significant threat to human health. Dengue virus (DENV) infection is one of the most noteworthy of these infections. According to a WHO survey, approximately 400 million people are infected annually; symptoms deteriorate in ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pilot Study to Detect DENGUE Virus in Sperm
 

Status: Not yet recruiting

Condition Summary: Dengue

 

Last Updated: 22 Aug 2018

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Last Updated: 14 Aug 2018

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The Use of Biomarkers in Predicting Dengue Outcome
 

Status: Recruiting

Condition Summary: Dengue

 

Last Updated: 24 Oct 2016

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