Depression

Common Name(s)

Depression

Depression is a condition in which a person feels discouraged, sad, hopeless, unmotivated, or disinterested in life in general. When these feelings last for a short period of time, it may be a case of "the blues." But when such feelings last for more than two weeks and interfere with daily activities such as taking care of family, spending time with friends, or going to work or school, it is a major depressive episode. Other symptoms may include changes in appetite and sleeping pattern, feelings of worthlessness or guilt, inability to concentrate, inability to find pleasure in former interests, social withdrawal, irritability, anger, anxiety, indecisiveness and unexplained aches and pains. Individuals with recurrent thoughts of suicide and death should seek immediate help either by contacting a suicide help line or going to a medical emergency center.

Depression is a medical illness involving an imbalance of brain chemicals. It is not a sign of personal weakness or character flaw. The exact cause of depression is unknown at this time. However, it is believed that depression may be caused by a combination of genetics and a stressful environment or life situation. Treatment of depression may include becoming involved with support groups, medications, and attending counseling sessions. Talk to your doctor to decide on the best treatment options if you or a family member has depression. Support groups are also a good source of up to date information and can help connect you with others affected by depression. Please also see: major depression, dysthymia, bipolar disorder, and postpartum depression.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Depression" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 24 Jun 2015

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Depression and Bipolar Support Alliance

The mission of DBSA is to provide hope, help, support and education to improve the lives of people who have mood disorders.

Last Updated: 15 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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The Balanced Mind Foundation

The Balanced Mind Foundation guides families raising children with mood disorders to the answers, support and stability they seek.

Last Updated: 18 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Depression" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 24 Jun 2015

View Details
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Depression and Bipolar Support Alliance

The mission of DBSA is to provide hope, help, support and education to improve the lives of people who have mood disorders.

http://www.ndmda.org

Last Updated: 15 Apr 2014

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

View Details
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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

View Details
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The Balanced Mind Foundation

The Balanced Mind Foundation guides families raising children with mood disorders to the answers, support and stability they seek.

http://www.thebalancedmind.org

Last Updated: 18 Oct 2012

View Details

 

General Support Organizations

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General Resources

Depression

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Depression" returned 12452 free, full-text research articles on human participants. First 3 results:

Prevalence of depression and anxiety among participants with glaucoma in a population-based cohort study: The Gutenberg Health Study.
 

Author(s): J Rezapour, S Nickels, A K Schuster, M Michal, T Münzel, P S Wild, I Schmidtmann, K Lackner, A Schulz, N Pfeiffer, M E Beutel

Journal:

 

To investigate the prevalence of depression and anxiety among subjects with self-reported glaucoma and the association between self-reported glaucoma and depression respectively anxiety in a European cohort.

Last Updated: 31 Dec 1969

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The association of different types of cerebral infarction with post-stroke depression and cognitive impairment.
 

Author(s): Jun Tu, Ling-Xiao Wang, Hong-Feng Wen, Yi-Cheng Xu, Pei-Fu Wang

Journal: Medicine (Baltimore). 2018 Jun;97(23):e10919.

 

The aim of this study was to investigate post-stroke depression (PSD) and cognitive impairments in patients with different types of cerebral infarction.A total of 110 patients with cerebral infarction treated in our hospital from January 2015 to February 2016 were included in present ...

Last Updated: 31 Dec 1969

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Relationship between Emotional Abuse and Depression among Community-Dwelling Older Adults in Korea.
 

Author(s): Jong Il Park

Journal: Yonsei Med. J.. 2018 Jul;59(5):693-697.

 

Despite recent advances, there is little research on factors associated with emotional abuse among Korean older adults. The present study investigated the relationships between depression and emotional abuse among community-dwelling Korean older adults. We analyzed the dataset from ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Depression" returned 1805 free, full-text review articles on human participants. First 3 results:

Efficacy, acceptability, and tolerability of antidepressant treatments for patients with post-stroke depression: a network meta-analysis.
 

Author(s): B Qin, H Chen, W Gao, L B Zhao, M J Zhao, H X Qin, W Chen, L Chen, M X Yang

Journal: Braz. J. Med. Biol. Res.. 2018 ;51(7):e7218.

 

The aim of this study was to investigate the efficacy, acceptability, and tolerability of antidepressants in treating post-stroke depression (PSD) by performing a network meta-analysis of randomized controlled trials of the current literature. Eligible studies were retrieved from ...

Last Updated: 31 Dec 1969

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Treatment of depression with Chai Hu Shu Gan San: a systematic review and meta-analysis of 42 randomized controlled trials.
 

Author(s): Yan Sun, Xia Xu, Jinping Zhang, Yuanyuan Chen

Journal:

 

Depression is a common mental disorder. Chai Hu Shu Gan San, a traditional Chinese medicine, is used to treat depression empirically. We present a systematic review and meta-analysis of the therapeutic efficacy and safety of Chai Hu Shu Gan San in treating depression.

Last Updated: 31 Dec 1969

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The effectiveness of acupuncture for chronic pain with depression: A systematic review protocol.
 

Author(s): Ziyi Yang, Ling Zhao, Xianze Xie, Tao Xu, Yutong Zhang, Xing Wang, Jiarong Du, Ziwen Wang, Mengyuan Zhou, Ying Li, Siyuan Zhou

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8800.

 

Chronic pain is a major public health problem and 30% to 45% of sufferers experience severe depression. Acupuncture is often used to treat both depression and a range of pain disorders. We aim to conduct a systematic review of randomized controlled trials (RCTs) to evaluate the efficacy ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Creatine Monohydrate Use for Preventing Altitude Induced Depression
 

Status: Not yet recruiting

Condition Summary: Depression

 

Last Updated: 8 Feb 2018

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Inflammatory Markers and Resistant Depression
 

Status: Not yet recruiting

Condition Summary: Depression

 

Last Updated: 25 Jul 2016

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Brief CBT for the Treatment of Depression During Inpatient Hospitalization
 

Status: Recruiting

Condition Summary: Depression

 

Last Updated: 24 Jan 2018

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