Developmental delay

Common Name(s)

Developmental delay

Developmental delay is a lag in one or more areas of development for a child. The major areas of childhood development include cognitive (intelligence and ability to process information), social and emotional (ability to interact with and appropriately respond to others), speech and language (ability to speak and understand language), fine motor (small movements), and gross motor (large movements). Children can have a delay in only one area of development, such as speech delay, or can have delay in all areas of development, called global developmental delay. It is important to keep in mind that there is a large range of normal development and each child develops at his or her own pace. However, any concern for development delay should be addressed.

Developmental delay can be caused by any number of inherited or acquired reasons, including an underlying genetic condition or metabolic disorder (Down syndrome, Fragile X syndrome, or phenylketonuria (PKU)), autism spectrum disorder, exposure to harmful agents before a baby is born (prenatal alcohol exposure, prenatal drug exposure, prenatal infection or poor maternal nutrition), and premature birth. Developmental delay is identified and diagnosed through developmental screenings and evaluations that are typically performed by a doctor or a specialist, such as a neuropsychologist. Treatment of developmental delay typically consists of therapies that focus on the area, or areas, of delay. Children with delays in language development typically receive speech therapy. Children with delays in fine motor development typically receive occupational therapy. Children with delays in gross motor development typically receive physical therapy. If an underlying treatable condition is identified as the reason for developmental delay, treatment of that condition may help improve development. Speak to your doctor about the best treatment options for your child.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Developmental delay" for support, advocacy or research.

Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Developmental delay" for support, advocacy or research.

Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Developmental delay" returned 244 free, full-text research articles on human participants. First 3 results:

Genomic diagnosis for children with intellectual disability and/or developmental delay.
 

Author(s): Kevin M Bowling, Michelle L Thompson, Michelle D Amaral, Candice R Finnila, Susan M Hiatt, Krysta L Engel, J Nicholas Cochran, Kyle B Brothers, Kelly M East, David E Gray, Whitley V Kelley, Neil E Lamb, Edward J Lose, Carla A Rich, Shirley Simmons, Jana S Whittle, Benjamin T Weaver, Amy S Nesmith, Richard M Myers, Gregory S Barsh, E Martina Bebin, Gregory M Cooper

Journal:

 

Developmental disabilities have diverse genetic causes that must be identified to facilitate precise diagnoses. We describe genomic data from 371 affected individuals, 309 of which were sequenced as proband-parent trios.

Last Updated: 30 May 2017

Go To URL
Novel missense mutation in the bZIP transcription factor, MAF, associated with congenital cataract, developmental delay, seizures and hearing loss (Aymé-Gripp syndrome).
 

Author(s): Shari Javadiyan, Jamie E Craig, Shiwani Sharma, Karen M Lower, Theresa Casey, Eric Haan, Emmanuelle Souzeau, Kathryn P Burdon

Journal:

 

Cataract is a major cause of severe visual impairment in childhood. The purpose of this study was to determine the genetic cause of syndromic congenital cataract in an Australian mother and son.

Last Updated: 9 May 2017

Go To URL
Factors Influencing the Gross Motor Outcome of Intensive Therapy in Children with Cerebral Palsy and Developmental Delay.
 

Author(s): Bo Young Hong, Leechan Jo, Joon Sung Kim, Seong Hoon Lim, Jung Min Bae

Journal: J. Korean Med. Sci.. 2017 May;32(5):873-879.

 

The study was designed to identify factors influencing the short term effect of intensive therapy on gross motor function in children with cerebral palsy or developmental delay. Retrospectively, total Gross Motor Function Measure-88 (GMFM-88) scores measured during the first and last ...

Last Updated: 5 Apr 2017

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Developmental delay" returned 19 free, full-text review articles on human participants. First 3 results:

Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, microcephaly, and developmental delay: Case report and literature review.
 

Author(s): Niu Li, Yufei Xu, Guoqiang Li, Tingting Yu, Ru-En Yao, Xiumin Wang, Jian Wang

Journal: Medicine (Baltimore). 2017 May;96(20):e6914.

 

The CTNNB1 (β-catenin) gene is well known for its crucial role in cell adhesion and the Wnt-signaling pathway. Previous studies have shown that gain-of-function mutations in the CTNNB1 gene contribute to the occurrence and development of a variety of carcinomas in humans. Recently, ...

Last Updated: 17 May 2017

Go To URL
Recommendations on screening for developmental delay.
 

Author(s): , Marcello Tonelli, Patricia Parkin, Paula Brauer, Denis Leduc, Kevin Pottie, Alejandra Jaramillo Garcia, Wendy Martin, Sarah Connor Gorber, Anne-Marie Ugnat, Marianna Ofner, Brett D. Thombs

Journal: CMAJ. 2016 05;188(8):579-87.

 

Last Updated: 17 May 2016

Go To URL
[Microdeletion 12p12 involving SOX5 gene: a new syndrome with developmental delay].
 

Author(s): Ignacio Arroyo-Carrera, M Solo de Zaldívar-Tristancho, Rebeca Martín-Fernández, Raquel Hernández-Martín, Amparo López-Lafuente, Laia Rodríguez-Revenga

Journal: Rev Neurol. 2015 May;60(10):453-6.

 

The SOX5 gene encodes a transcription factor involved in the regulation of chondrogenesis and the development of the nervous system.

Last Updated: 8 May 2015

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Insoles on Children With Developmental Delays
 

Status: Not yet recruiting

Condition Summary: Developmental Delay

 

Last Updated: 22 Jun 2017

Go to URL

Last Updated: 15 Aug 2017

Go to URL
Effects of Family Work Shop for Children With Developmental Delays: a Randomized Trial
 

Status: Not yet recruiting

Condition Summary: Development Delay

 

Last Updated: 4 Jul 2017

Go to URL