Developmental delay

Common Name(s)

Developmental delay

Developmental delay is a lag in one or more areas of development for a child. The major areas of childhood development include cognitive (intelligence and ability to process information), social and emotional (ability to interact with and appropriately respond to others), speech and language (ability to speak and understand language), fine motor (small movements), and gross motor (large movements). Children can have a delay in only one area of development, such as speech delay, or can have delay in all areas of development, called global developmental delay. It is important to keep in mind that there is a large range of normal development and each child develops at his or her own pace. However, any concern for development delay should be addressed.

Developmental delay can be caused by any number of inherited or acquired reasons, including an underlying genetic condition or metabolic disorder (Down syndrome, Fragile X syndrome, or phenylketonuria (PKU)), autism spectrum disorder, exposure to harmful agents before a baby is born (prenatal alcohol exposure, prenatal drug exposure, prenatal infection or poor maternal nutrition), and premature birth. Developmental delay is identified and diagnosed through developmental screenings and evaluations that are typically performed by a doctor or a specialist, such as a neuropsychologist. Treatment of developmental delay typically consists of therapies that focus on the area, or areas, of delay. Children with delays in language development typically receive speech therapy. Children with delays in fine motor development typically receive occupational therapy. Children with delays in gross motor development typically receive physical therapy. If an underlying treatable condition is identified as the reason for developmental delay, treatment of that condition may help improve development. Speak to your doctor about the best treatment options for your child.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Developmental delay" for support, advocacy or research.

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Developmental delay" for support, advocacy or research.

Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Developmental delay" returned 253 free, full-text research articles on human participants. First 3 results:

De novo chromosome 7q36.1q36.2 triplication in a child with developmental delay, growth failure, distinctive facial features, and multiple congenital anomalies: a case report.
 

Author(s): Muna A Al Dhaibani, Diane Allingham-Hawkins, Ayman W El-Hattab

Journal:

 

Studying human genome using chromosomal microarrays has significantly improved the accuracy and yield of diagnosing genomic disorders. Chromosome 7q36 deletions and duplications are rare genomic disorders that have been reported in a limited number of children with developmental delay, ...

Last Updated: 24 Oct 2017

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Genomic diagnosis for children with intellectual disability and/or developmental delay.
 

Author(s): Kevin M Bowling, Michelle L Thompson, Michelle D Amaral, Candice R Finnila, Susan M Hiatt, Krysta L Engel, J Nicholas Cochran, Kyle B Brothers, Kelly M East, David E Gray, Whitley V Kelley, Neil E Lamb, Edward J Lose, Carla A Rich, Shirley Simmons, Jana S Whittle, Benjamin T Weaver, Amy S Nesmith, Richard M Myers, Gregory S Barsh, E Martina Bebin, Gregory M Cooper

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Developmental disabilities have diverse genetic causes that must be identified to facilitate precise diagnoses. We describe genomic data from 371 affected individuals, 309 of which were sequenced as proband-parent trios.

Last Updated: 30 May 2017

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Novel missense mutation in the bZIP transcription factor, MAF, associated with congenital cataract, developmental delay, seizures and hearing loss (Aymé-Gripp syndrome).
 

Author(s): Shari Javadiyan, Jamie E Craig, Shiwani Sharma, Karen M Lower, Theresa Casey, Eric Haan, Emmanuelle Souzeau, Kathryn P Burdon

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Cataract is a major cause of severe visual impairment in childhood. The purpose of this study was to determine the genetic cause of syndromic congenital cataract in an Australian mother and son.

Last Updated: 9 May 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Developmental delay" returned 20 free, full-text review articles on human participants. First 3 results:

Current evidence-based recommendations on investigating children with global developmental delay.
 

Author(s): Renuka Mithyantha, Rachel Kneen, Emma McCann, Melissa Gladstone

Journal: Arch. Dis. Child.. 2017 Nov;102(11):1071-1076.

 

Global developmental delay (GDD) affects 1%-3% of the population of children under 5 years of age, making it one of the most common conditions presenting in paediatric clinics; causes are exogenous, genetic (non-metabolic) or genetic (metabolic). Recent advances in biotechnology ...

Last Updated: 21 Oct 2017

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Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, microcephaly, and developmental delay: Case report and literature review.
 

Author(s): Niu Li, Yufei Xu, Guoqiang Li, Tingting Yu, Ru-En Yao, Xiumin Wang, Jian Wang

Journal: Medicine (Baltimore). 2017 May;96(20):e6914.

 

The CTNNB1 (β-catenin) gene is well known for its crucial role in cell adhesion and the Wnt-signaling pathway. Previous studies have shown that gain-of-function mutations in the CTNNB1 gene contribute to the occurrence and development of a variety of carcinomas in humans. Recently, ...

Last Updated: 17 May 2017

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Recommendations on screening for developmental delay.
 

Author(s): , Marcello Tonelli, Patricia Parkin, Paula Brauer, Denis Leduc, Kevin Pottie, Alejandra Jaramillo Garcia, Wendy Martin, Sarah Connor Gorber, Anne-Marie Ugnat, Marianna Ofner, Brett D. Thombs

Journal: CMAJ. 2016 05;188(8):579-87.

 

Last Updated: 17 May 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Insoles on Children With Developmental Delays
 

Status: Not yet recruiting

Condition Summary: Developmental Delay

 

Last Updated: 22 Jun 2017

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Last Updated: 15 Aug 2017

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Effects of Family Work Shop for Children With Developmental Delays: a Randomized Trial
 

Status: Not yet recruiting

Condition Summary: Development Delay

 

Last Updated: 4 Jul 2017

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