Developmental delay

Common Name(s)

Developmental delay

Developmental delay is a lag in one or more areas of development for a child. The major areas of childhood development include cognitive (intelligence and ability to process information), social and emotional (ability to interact with and appropriately respond to others), speech and language (ability to speak and understand language), fine motor (small movements), and gross motor (large movements). Children can have a delay in only one area of development, such as speech delay, or can have delay in all areas of development, called global developmental delay. It is important to keep in mind that there is a large range of normal development and each child develops at his or her own pace. However, any concern for development delay should be addressed.

Developmental delay can be caused by any number of inherited or acquired reasons, including an underlying genetic condition or metabolic disorder (Down syndrome, Fragile X syndrome, or phenylketonuria (PKU)), autism spectrum disorder, exposure to harmful agents before a baby is born (prenatal alcohol exposure, prenatal drug exposure, prenatal infection or poor maternal nutrition), and premature birth. Developmental delay is identified and diagnosed through developmental screenings and evaluations that are typically performed by a doctor or a specialist, such as a neuropsychologist. Treatment of developmental delay typically consists of therapies that focus on the area, or areas, of delay. Children with delays in language development typically receive speech therapy. Children with delays in fine motor development typically receive occupational therapy. Children with delays in gross motor development typically receive physical therapy. If an underlying treatable condition is identified as the reason for developmental delay, treatment of that condition may help improve development. Speak to your doctor about the best treatment options for your child.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Developmental delay" for support, advocacy or research.

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Developmental delay" for support, advocacy or research.

Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Developmental delay" returned 278 free, full-text research articles on human participants. First 3 results:

Phenotypic Analysis of Korean Patients with Abnormal Chromosomal Microarray in Patients with Unexplained Developmental Delay/Intellectual Disability.
 

Author(s): Hyo Jeong Kim, Chang Il Park, Jae Woo Lim, Gyung Min Lee, Eunhae Cho, Hyon J Kim

Journal: Yonsei Med. J.. 2018 May;59(3):431-437.

 

The present study aimed to investigate chromosomal microarray (CMA) and clinical data in patients with unexplained developmental delay/intellectual disability (DD/ID) accompanying dysmorphism, congenital anomalies, or epilepsy. We also aimed to evaluate phenotypic clues in patients ...

Last Updated: 31 Dec 1969

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Vocalization of Emotional and Social Expressions in Korean-Speaking Toddlers with Autism Spectrum Disorder and Those with Developmental Delay.
 

Author(s): Kyung Sook Lee, Yee Jin Shin, Hee Jeong Yoo, Gui Jong Lee, Jeong Ryu, Oweol Son, Sook Whan Cho

Journal: Yonsei Med. J.. 2018 May;59(3):425-430.

 

This study aimed to examine the development of socializing and emotional expressions through vocalizations and joint attention (JA) behaviors in Korean-speaking children with autism spectrum disorder (ASD), compared to those with developmental delay (DD).

Last Updated: 31 Dec 1969

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Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism.
 

Author(s): Kit San Yeung, Winnie Wan Yee Tso, Janice Jing Kun Ip, Christopher Chun Yu Mak, Gordon Ka Chun Leung, Mandy Ho Yin Tsang, Dingge Ying, Steven Lim Cho Pei, So Lun Lee, Wanling Yang, Brian Hon-Yin Chung

Journal:

 

Macrocephaly, which is defined as a head circumference greater than or equal to + 2 standard deviations, is a feature commonly observed in children with developmental delay and/or autism spectrum disorder. Although is a well-known gene identified in patients with this syndromic ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Developmental delay" returned 21 free, full-text review articles on human participants. First 3 results:

Current evidence-based recommendations on investigating children with global developmental delay.
 

Author(s): Renuka Mithyantha, Rachel Kneen, Emma McCann, Melissa Gladstone

Journal: Arch. Dis. Child.. 2017 11;102(11):1071-1076.

 

Global developmental delay (GDD) affects 1%-3% of the population of children under 5 years of age, making it one of the most common conditions presenting in paediatric clinics; causes are exogenous, genetic (non-metabolic) or genetic (metabolic). Recent advances in biotechnology ...

Last Updated: 31 Dec 1969

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Partial monosomy 8p and trisomy 16q in two children with developmental delay detected by array comparative genomic hybridization.
 

Author(s): Zoe Papadopoulou, Ioannis Papoulidis, Stavros Sifakis, Georgios Markopoulos, Annalisa Vetro, Angeliki-Maria Vlaikou, Monica Ziegler, Thomas Liehr, Loretta Thomaidis, Orsetta Zuffardi, Maria Syrrou, Kitsos George, Emmanouil Manolakos

Journal: Mol Med Rep. 2017 Dec;16(6):8808-8818.

 

Two cases of liveborn unrelated children with developmental delay and overlapping unbalanced translocations der(8)t(8;16)(p23.2;q23.3) and der (8)t(8;16)(p23.1;q23.1), leading to partial monosomy 8p and partial trisomy 16q, are reported in the present study. The first patient was ...

Last Updated: 31 Dec 1969

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Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, microcephaly, and developmental delay: Case report and literature review.
 

Author(s): Niu Li, Yufei Xu, Guoqiang Li, Tingting Yu, Ru-En Yao, Xiumin Wang, Jian Wang

Journal: Medicine (Baltimore). 2017 May;96(20):e6914.

 

The CTNNB1 (β-catenin) gene is well known for its crucial role in cell adhesion and the Wnt-signaling pathway. Previous studies have shown that gain-of-function mutations in the CTNNB1 gene contribute to the occurrence and development of a variety of carcinomas in humans. Recently, ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Insoles on Children With Developmental Delays
 

Status: Not yet recruiting

Condition Summary: Developmental Delay

 

Last Updated: 22 Jun 2017

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Last Updated: 15 Aug 2017

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Effects of Family Work Shop for Children With Developmental Delays: a Randomized Trial
 

Status: Not yet recruiting

Condition Summary: Development Delay

 

Last Updated: 4 Jul 2017

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