Diabetes Insipidus

Common Name(s)

Diabetes Insipidus

Diabetes insipidus is a condition where the kidneys do not function properly, causing individuals to have to urinate frequently and often become dehydrated. Normally, the kidneys, which are small organs located in the abdomen (belly), filter a person’s blood multiple times a day and create urine. However, when a person has diabetes insipidus, they filter out too much water and create too much urine. This causes the individual to have to urinate more frequently, often every hour of the day and night. There are different types of diabetes insipidus depending on the actual chemical cause of the disorder. Onset of diabetes insipidus can occur at any age beyond infancy. Most symptoms of diabetes insipidus can be controlled with medication, and depending on the cause, it may sometimes resolve after a period of time. During this time, however, it is important to have a physician manage the condition to prevent dehydration or other potential consequences of diabetes insipidus. The frequency of diabetes insipidus is 3 in every 100,000 people.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes Insipidus" for support, advocacy or research.

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Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes Insipidus" for support, advocacy or research.

Logo
Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

http://www.pituitary.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes Insipidus" returned 454 free, full-text research articles on human participants. First 3 results:

Nephrogenic diabetes insipidus in initial stage of acute lymphoblastic leukemia and relapse after haploidentical hematopoietic stem-cell transplantation: A case report.
 

Author(s): Dezhi Li, Qian Liu, Zhifang Feng, Qi Zhang, Saran Feng

Journal: Medicine (Baltimore). 2018 Jun;97(24):e11157.

 

Nephrogenic diabetes insipidus (NDI) rarely presents in the initial stage of acute lymphoblastic leukemia (ALL) and relapse due to renal infiltration is also rare.

Last Updated: 31 Dec 1969

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[Alobar holoprosencephaly associated with diabetes insipidus and hypothyroidism in a 10-month old infant].
 

Author(s): Ndiogou Seck, Idrissa Basse, Younoussa Keita, Djiril Boiro, Lamine Thiam, Aliou Adoulaye Ndongo, Ibrahima Diagne

Journal:

 

Holoprosencephaly (HPE) is a serious brain malformation due to a failure of medial forebrain cleavage. This is an abnormality which is more often associated with craniofacial malformations, psychomotor development delay, diabetes insipidus and variable endocrine disorders. It is due ...

Last Updated: 31 Dec 1969

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Treatment of congenital nephrogenic diabetes insipidus in pregnancy.
 

Author(s): Agnieszka Gala-Błądzińska, Adam Mrozek, Aleksandra Kędzior, Artur Mazur, Dorota Darmochwał-Kolarz

Journal: Ginekol. Pol.. 2018 ;89(2):112-113.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes Insipidus" returned 32 free, full-text review articles on human participants. First 3 results:

Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update.
 

Author(s): Serena Milano, Monica Carmosino, Andrea Gerbino, Maria Svelto, Giuseppe Procino

Journal:

 

Under physiological conditions, excessive loss of water through the urine is prevented by the release of the antidiuretic hormone arginine-vasopressin (AVP) from the posterior pituitary. In the kidney, AVP elicits a number of cellular responses, which converge on increasing the osmotic ...

Last Updated: 31 Dec 1969

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Overlap of Post-obstructive Diuresis and Unmasked Diabetes Insipidus in a Case of IgG4-related Retroperitoneal Fibrosis and Tuberoinfundibular Hypophysitis: A Case Report and Review of the Literature.
 

Author(s): Midori Sasaki Yatabe, Kimio Watanabe, Yoshimitsu Hayashi, Junichi Yatabe, Satoshi Morimoto, Atsuhiro Ichihara, Masaaki Nakayama, Tsuyoshi Watanabe

Journal: Intern. Med.. ;56(1):47-53.

 

The clinical picture of IgG4-related disease (IgG4-RD) is diverse because various organs can be affected. We describe the case of a 56-year-old man with acute renal failure and tuberoinfundibular hypophysitis due to IgG4-RD. Steroid therapy lowered the serum IgG4 level and ameliorated ...

Last Updated: 31 Dec 1969

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Physiological insights into novel therapies for nephrogenic diabetes insipidus.
 

Author(s): Jeff M Sands, Janet D Klein

Journal: Am. J. Physiol. Renal Physiol.. 2016 12;311(6):F1149-F1152.

 

Fundamental kidney physiology research can provide important insight into how the kidney works and suggest novel therapeutic opportunities to treat human diseases. This is especially true for nephrogenic diabetes insipidus (NDI). Over the past decade, studies elucidating the molecular ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Atorvastatin for the Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus
 

Status: Recruiting

Condition Summary: Lithium Use, Nephrogenic Diabetes Insipidus

 

Last Updated: 12 Oct 2017

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Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study
 

Status: Not yet recruiting

Condition Summary: Diabetes Insipidus; Polydipsia, Primary

 

Last Updated: 13 Jul 2018

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Copeptin Serum Level in Liver Transplant Recipients
 

Status: Recruiting

Condition Summary: Liver Cirrhosis; Copeptin; Liver Transplant

 

Last Updated: 13 Jul 2018

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