Diabetes Insipidus

Common Name(s)

Diabetes Insipidus

Diabetes insipidus is a condition where the kidneys do not function properly, causing individuals to have to urinate frequently and often become dehydrated. Normally, the kidneys, which are small organs located in the abdomen (belly), filter a person’s blood multiple times a day and create urine. However, when a person has diabetes insipidus, they filter out too much water and create too much urine. This causes the individual to have to urinate more frequently, often every hour of the day and night. There are different types of diabetes insipidus depending on the actual chemical cause of the disorder. Onset of diabetes insipidus can occur at any age beyond infancy. Most symptoms of diabetes insipidus can be controlled with medication, and depending on the cause, it may sometimes resolve after a period of time. During this time, however, it is important to have a physician manage the condition to prevent dehydration or other potential consequences of diabetes insipidus. The frequency of diabetes insipidus is 3 in every 100,000 people.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes Insipidus" for support, advocacy or research.

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Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes Insipidus" for support, advocacy or research.

Logo
Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

http://www.pituitary.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes Insipidus" returned 448 free, full-text research articles on human participants. First 3 results:

Diabetes Insipidus Presenting with Oligohydramnios and Polyuria During Pregnancy.
 

Author(s): Hong Sang Choi, Yoon Ha Kim, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae

Journal: J Nippon Med Sch. 2018 ;85(3):191-193.

 

We report a case of subclinical central diabetes insipidus (DI), due to Rathke's cleft cysts, that was initially misdiagnosed as transient DI of pregnancy because it presented in the third trimester of pregnancy. A 37-year-old primigravida visited the Department of Obstetrics in the ...

Last Updated: 31 Dec 1969

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Nephrogenic diabetes insipidus in initial stage of acute lymphoblastic leukemia and relapse after haploidentical hematopoietic stem-cell transplantation: A case report.
 

Author(s): Dezhi Li, Qian Liu, Zhifang Feng, Qi Zhang, Saran Feng

Journal: Medicine (Baltimore). 2018 Jun;97(24):e11157.

 

Nephrogenic diabetes insipidus (NDI) rarely presents in the initial stage of acute lymphoblastic leukemia (ALL) and relapse due to renal infiltration is also rare.

Last Updated: 31 Dec 1969

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[Alobar holoprosencephaly associated with diabetes insipidus and hypothyroidism in a 10-month old infant].
 

Author(s): Ndiogou Seck, Idrissa Basse, Younoussa Keita, Djiril Boiro, Lamine Thiam, Aliou Adoulaye Ndongo, Ibrahima Diagne

Journal:

 

Holoprosencephaly (HPE) is a serious brain malformation due to a failure of medial forebrain cleavage. This is an abnormality which is more often associated with craniofacial malformations, psychomotor development delay, diabetes insipidus and variable endocrine disorders. It is due ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes Insipidus" returned 32 free, full-text review articles on human participants. First 3 results:

Severe localised granulomatosis with polyangiitis (Wegener's granulomatosis) manifesting with extensive cranial nerve palsies and cranial diabetes insipidus: a case report and literature review.
 

Author(s): James E Peters, Vivek Gupta, Ibtisam T Saeed, Curtis Offiah, Ali S M Jawad

Journal:

 

Granulomatosis with polyangiitis (GPA, formerly Wegener's granulomatosis) is a multisystem vasculitis of small- to medium-sized blood vessels. Cranial involvement can result in cranial nerve palsies and, rarely, pituitary infiltration.

Last Updated: 31 Dec 1969

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Activation of AQP2 water channels without vasopressin: therapeutic strategies for congenital nephrogenic diabetes insipidus.
 

Author(s): Fumiaki Ando, Shinichi Uchida

Journal: Clin. Exp. Nephrol.. 2018 Jun;22(3):501-507.

 

Congenital nephrogenic diabetes insipidus (NDI) is characterized by defective urine concentrating ability. Symptomatic polyuria is present from birth, even with normal release of the antidiuretic hormone vasopressin by the pituitary. Over the last two decades, the aquaporin-2 (AQP2) ...

Last Updated: 31 Dec 1969

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Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update.
 

Author(s): Serena Milano, Monica Carmosino, Andrea Gerbino, Maria Svelto, Giuseppe Procino

Journal:

 

Under physiological conditions, excessive loss of water through the urine is prevented by the release of the antidiuretic hormone arginine-vasopressin (AVP) from the posterior pituitary. In the kidney, AVP elicits a number of cellular responses, which converge on increasing the osmotic ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Atorvastatin for the Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus
 

Status: Recruiting

Condition Summary: Lithium Use, Nephrogenic Diabetes Insipidus

 

Last Updated: 12 Oct 2017

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Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study
 

Status: Recruiting

Condition Summary: Diabetes Insipidus; Polydipsia, Primary

 

Last Updated: 10 Oct 2018

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Copeptin Serum Level in Liver Transplant Recipients
 

Status: Recruiting

Condition Summary: Liver Cirrhosis; Copeptin; Liver Transplant

 

Last Updated: 9 Oct 2018

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