Diabetes mellitus type 1

Common Name(s)

Diabetes mellitus type 1

Diabetes mellitus type 1 (DM1) is a condition in which cells in the pancreas (beta cells) stop producing insulin, causing abnormally high blood sugar levels. Lack of insulin results in the inability of the body to use glucose for energy and control the amount of sugar in the blood. DM1 can occur at any age, but usually develops by early adulthood, most often in adolescence. Symptoms of high blood sugar may include frequent urination, excessive thirst, fatigue, blurred vision, tingling or loss of feeling in the hands and feet, and weight loss. The exact cause of DM1 is unknown, but having certain "variants" of specific genes may increase a person's risk to develop the condition. A predisposition to develop DM1 runs in families, but no known inheritance pattern exists. Treatment includes blood sugar control and insulin replacement therapy. Improper control can cause recurrence of high blood sugar, or abnormally low blood sugar (hypoglycemia) during exercise or when eating is delayed. If not treated, the condition can be life-threatening. Over many years, chronic high blood sugar may be associated with a variety of complications that affect many parts of the body.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 1" for support, advocacy or research.

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Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 1" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 1" returned 865 free, full-text research articles on human participants. First 3 results:

Novel Polysaccharide H-1-2 from Pseudostellaria Heterophylla Alleviates Type 2 Diabetes Mellitus.
 

Author(s): Zhao-Hui Fang, Xian-Chun Duan, Jin-Dong Zhao, Yuan-Jie Wu, Meng-Meng Liu

Journal: Cell. Physiol. Biochem.. 2018 ;49(3):996-1006.

 

To investigate the potential therapeutic effect of novel polysaccharide H-1-2 from pseudostellaria heterophylla against type 2 Diabetes Mellitus (T2DM) and elucidate the underling molecular mechanisms.

Last Updated: 31 Dec 1969

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Risk factors for development and progression of diabetic retinopathy in Dutch patients with type 1 diabetes mellitus.
 

Author(s): Vivian Schreur, Freekje van Asten, Heijan Ng, Jack Weeda, Joannes M M Groenewoud, Cees J Tack, Carel B Hoyng, Eiko K de Jong, Caroline C W Klaver, B Jeroen Klevering

Journal: Acta Ophthalmol. 2018 Aug;96(5):459-464.

 

To investigate risk factors for the development and progression of diabetic retinopathy (DR) and long-term visual outcomes in Dutch patients with type 1 diabetes mellitus (T1DM).

Last Updated: 31 Dec 1969

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Free Style Libre Pro (FSLP) Flash Glucose Monitor (FGM) - A Novel Monitoring Tool for Children with Type 1 Diabetes Mellitus.
 

Author(s): Sridevi A Naaraayan, Poovazhagi Varadharajan, Raghavan Velayutham Dhakshayani, Rema Chandramohan, Senthil Senniappan

Journal: Indian Pediatr. 2018 06;55(6):524-525.

 

Flash glucose monitoring using Free Style Libre Pro (FSLP) was undertaken among fifteen diabetic children. Data revealed high glycaemic variability, Time in Target Range (TIR) to be 27% and 12% of time in hypoglycaemia. Sensor insertion and retention were problematic in 33%. Though ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 1" returned 111 free, full-text review articles on human participants. First 3 results:

[Psychosocial impact of type 1 diabetes mellitus in children, adolescents and their families. Literature review].
 

Author(s): Rocío Henríquez-Tejo, Ricardo Cartes-Velásquez

Journal: Rev Chil Pediatr. 2018 Jun;89(3):391-398.

 

Type 1 diabetes mellitus is the most common chronic endocrine pathology among children. Treatment includes diet, physical activity, insulin medication, and proper self-control. This self-control may be difficult, resulting in children, adolescents and their families suffering diverse ...

Last Updated: 31 Dec 1969

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Effectiveness and safety of carbohydrate counting in the management of adult patients with type 1 diabetes mellitus: a systematic review and meta-analysis.
 

Author(s): Eliege Carolina Vaz, Gustavo José Martiniano Porfírio, Hélio Rubens de Carvalho Nunes, Vania Dos Santos Nunes-Nogueira

Journal: Arch Endocrinol Metab. 2018 Jun;62(3):337-345.

 

This study aimed to evaluate the effectiveness and safety of carbohydrate counting (CHOC) in the treatment of adult patients with type 1 diabetes mellitus (DM1).

Last Updated: 31 Dec 1969

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Low-carbohydrate diets for type 1 diabetes mellitus: A systematic review.
 

Author(s): Jessica L Turton, Ron Raab, Kieron B Rooney

Journal:

 

Type 1 diabetes is an autoimmune condition characterised by pancreatic beta cell destruction and absolute insulin deficiency. The strongest predictor of diabetes complications is glycaemic control and achieving HbA1c ≤ 7.0% is the primary management target. However, standard treatment ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Stem Cells in Diabetes Mellitus Type 1
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 1

 

Last Updated: 5 Jun 2018

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A Pilot Study of the Therapeutic Potential of Stem Cell Educator Therapy in Type 1 Diabetes
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 1

 

Last Updated: 7 Aug 2018

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Continuous Glucose Monitoring During Intecorse in Young Adults With Type 1 Diabetes
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 1

 

Last Updated: 18 Oct 2017

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