Diabetes mellitus type 2

Common Name(s)

Diabetes mellitus type 2, Type 2 diabetes

Type 2 diabetes mellitus is a metabolic disease in which a person has high blood sugar or glucose levels. Glucose is the main energy or fuel source for our body’s cells. Insulin helps our body’s cells take in the glucose from our bloodstream. Type 2 diabetes can result because the pancreas cannot produce enough insulin or due to an inability of the body's cells to recognize insulin. Therefore lack of insulin or the inability of cells to recognize insulin results in increased or high blood glucose levels. Early symptoms may include an increased thirst and hunger, weight loss, fatigue, blurred vision, slow-healing sores or increased infections, and darkened areas of skin.

Rates of type 2 diabetes have gone up recently, especially in younger people, as obesity rates have also increased. Other risk factors include fat distributed mainly in the belly, inactivity, family history, race, and age. Uncontrolled blood glucose levels for an extended period of time can cause damage to blood vessels, the kidney, nerves, eyes, feet, skin and mouth, hearing, and greatly increases the risk of cardiovascular problems such as heart disease and heart attack. There's no cure for type 2 diabetes, but you may be able to manage the condition by eating well, exercising and maintaining a healthy weight. If diet and exercise aren't enough to manage your blood sugar well, you also may need diabetes medications or insulin therapy. If you or a family member has been diagnosed with type 2 diabetes, talk with your doctor about treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

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Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 2" returned 2738 free, full-text research articles on human participants. First 3 results:

Diagnostic value of carotid artery ultrasound and hypersensitive C-reactive protein in Type 2 diabetes mellitus patients with acute myocardial infarction in Chinese population.
 

Author(s): Juan Li, Liangliang Wang, Qian Wang, Zhaoqin Xin, Yilin Liu, Qinghua Zhao

Journal: Medicine (Baltimore). 2018 Oct;97(41):e12334.

 

Hypersensitive C-reactive protein (hs-CRP) is reported to be significant risk indicators not only for the development of cardiovascular disease, but also for the development or progression of type 2 diabetes. The objective of this study was to analyze the significance of hs-CRP in ...

Last Updated: 31 Dec 1969

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Characteristics of repaglinide and its mechanism of action on insulin secretion in patients with newly diagnosed type-2 diabetes mellitus.
 

Author(s): Liang-Chen Wang, Fu-Sheng Fang, Yan-Ping Gong, Guang Yang, Chun-Lin Li

Journal: Medicine (Baltimore). 2018 Sep;97(38):e12476.

 

This study aims to compare the effect of repaglinide and metformin among Chinese patients with newly diagnosed diabetes, and explore the possible mechanisms by which repaglinide alters insulin secretion.Sixty subjects with glycated hemoglobin (HbA1c) < 10.0% were randomly selected ...

Last Updated: 31 Dec 1969

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Risk factors associated with nonalcohol fatty liver disease and fibrosis among patients with type 2 diabetes mellitus.
 

Author(s): Hongli Zhao, Xiangxin Song, Zhang Li, Xinling Wang

Journal: Medicine (Baltimore). 2018 Sep;97(37):e12356.

 

Type 2 diabetes mellitus (T2DM) is closely related to hepatic steatosis and fibrosis. The aim of this study was to analyze the occurrence of hepatic steatosis and fibrosis in patients with T2DM and to explore the risk factors.A total of 629 patients with T2DM were enrolled. Liver ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 2" returned 398 free, full-text review articles on human participants. First 3 results:

The efficacy and safety of once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus: A systemic review and meta-analysis.
 

Author(s): Xianying Wang, Xuejing Li, Suhui Qie, Yingying Zheng, Yang Liu, Guoqiang Liu

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11946.

 

The efficacy and safety of once-weekly dipeptidyl peptidase-4 inhibitor (DPP-4i) omarigliptin as monotherapy or add on to other antihyperglycemic agents (AHAs) in patients with type 2 diabetes mellitus (T2DM) is unclear.

Last Updated: 31 Dec 1969

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Association of metformin intake with bladder cancer risk and oncologic outcomes in type 2 diabetes mellitus patients: A systematic review and meta-analysis.
 

Author(s): Jiao Hu, Jin-Bo Chen, Yu Cui, Ye-Wen Zhu, Wen-Biao Ren, Xu Zhou, Long-Fei Liu, He-Qun Chen, Xiong-Bing Zu

Journal: Medicine (Baltimore). 2018 Jul;97(30):e11596.

 

Recent clinical trials indicated that metformin intake might play a protective role in the incidence and oncologic outcomes of various cancers. However, its protective effect on bladder cancer remains uncertain.

Last Updated: 31 Dec 1969

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[Exercise and oxidative stress in type 2 diabetes mellitus].
 

Author(s): Carlos Poblete-Aro, Javier Russell-Guzmán, Pablo Parra, Marcelo Soto-Muñoz, Bastián Villegas-González, Cristián Cofré-Bolados, Tomás Herrera-Valenzuela

Journal: Rev Med Chil. 2018 Mar;146(3):362-372.

 

Sedentarism, overweight and malnutrition generate an increase in the production of reactive oxygen species leading to a state of chronic oxidative stress. In patients with type 2 diabetes mellitus, oxidative stress alters pancreatic insulin secretion and the actions of the hormone ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Oct 2018

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Last Updated: 21 Dec 2017

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HbA1c Variability in Type II Diabetes
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2

 

Last Updated: 1 Jun 2017

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