Diffuse Panbronchiolitis

Common Name(s)

Diffuse Panbronchiolitis

Diffuse panbronchiolitis (DPB) is a rare chronic inflammatory obstructive pulmonary disease primarily affecting the respiratory bronchioles. 'Diffuse' refers to the distribution of the lesions throughout both lungs, and 'pan-' refers to the involvement of inflammation in all layers of the respiratory bronchioles. Onset of the disorder occurs in the second to fifth decade of life, and is clinically manifest by chronic cough, exertional dyspnea, and sputum production. Most patients also have chronic paranasal sinusitis. If untreated, the disorder progresses to bronchiectasis, respiratory failure, and death (summary by {10:Poletti et al., 2006}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diffuse Panbronchiolitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diffuse Panbronchiolitis" returned 66 free, full-text research articles on human participants. First 3 results:

An Autopsy Case Report of Adult T-cell Leukemia Accompanied by Rheumatoid Arthritis Mimicking Diffuse Panbronchiolitis.
 

Author(s): Tomoko Shiraishi, Hiroshi Ishimoto, Kentaro Akata, Toshinori Kawanami, Kazuhiro Yatera, Hiroshi Mukae

Journal: J. UOEH. 2017 ;39(1):55-61.

 

A 50-year-old female with a history of chronic sinusitis and rheumatoid arthritis visited our department with repetitive lower respiratory tract infections of Pseudomonas aeruginosa. Her chest CT showed diffuse panbronchiolitis-like pulmonary lesions, her blood examination revealed ...

Last Updated: 31 Dec 1969

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eComment. Benefits of macrolide usage and bacteriological profile in patients with diffuse panbronchiolitis.
 

Author(s): Tomislav Mestrovic, Marijana Neuberg

Journal: Interact Cardiovasc Thorac Surg. 2016 05;22(5):681.

 

Last Updated: 31 Dec 1969

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Lung transplantation for diffuse panbronchiolitis: 5 cases from a single centre.
 

Author(s): Seiichiro Sugimoto, Kentaroh Miyoshi, Masaomi Yamane, Takahiro Oto

Journal: Interact Cardiovasc Thorac Surg. 2016 05;22(5):679-81.

 

Diffuse panbronchiolitis is a rare complex genetic disease predominantly affecting East Asians, and is characterized by chronic inflammation of the respiratory bronchioles and sinobronchial infection. Although long-term macrolide therapy has been shown to significantly improve the ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diffuse Panbronchiolitis" returned 3 free, full-text review articles on human participants. First 3 results:

Primary ciliary dyskinesia complicated with diffuse panbronchiolitis: a case report and literature review.
 

Author(s): Wei Chen, Changzhou Shao, Yuanlin Song, Chunxue Bai

Journal: Clin Respir J. 2014 Oct;8(4):425-30.

 

Fifty percent of patients with primary ciliary dyskinesia (PCD) have situs inversus. Diffuse panbronchiolitis (DPB) might be one of the characteristic features of the lung in PCD.

Last Updated: 31 Dec 1969

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Diffuse panbronchiolitis.
 

Author(s): V Poletti, G Casoni, M Chilosi, M Zompatori

Journal: Eur. Respir. J.. 2006 Oct;28(4):862-71.

 

Diffuse panbronchiolitis (DPB) is an idiopathic inflammatory disease, well recognised in Japan and principally affecting the respiratory bronchioles, causing a progressive suppurative and severe obstructive respiratory disorder. If left untreated, DPB progresses to bronchiectasis, ...

Last Updated: 31 Dec 1969

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Erythromycin and diffuse panbronchiolitis.
 

Author(s): H Koyama, D M Geddes

Journal: Thorax. 1997 Oct;52(10):915-8.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.