Diphtheria

Common Name(s)

Diphtheria

Diphtheria is a rare and serious bacterial infection that affects the function of mucous membranes in the nose and throat. The bacteria get passed from person to person through contaminated personal or household items and airborne infected droplets. Young children and elderly people are at higher risk of getting diphtheria. Symptoms of diphtheria include gray/black mucus covering the throat and tonsils, sore throat, swollen glands, difficulty breathing, fever and chills, nasal discharge, and an overall feeling of discomfort (malaise). An antitoxin, which counteracts the toxin of the bacteria, as well as antibiotics, can be used to treat diphtheria. Some people with diphtheria may need hospitalization or surgery to remove the lining in the throat. There is a vaccination for diphtheria that effectively prevents the bacterial infection for many individuals and is part of the routine childhood vaccinations in most parts of the world.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diphtheria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diphtheria" returned 676 free, full-text research articles on human participants. First 3 results:

Carrier study and treatment of close contacts: A must for diphtheria eradication.
 

Author(s): Usha Udgaonkar

Journal: Indian J Med Microbiol. ;36(1):148.

 

Last Updated: 31 Dec 1969

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Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP).
 

Author(s): Jennifer L Liang, Tejpratap Tiwari, Pedro Moro, Nancy E Messonnier, Arthur Reingold, Mark Sawyer, Thomas A Clark

Journal:

 

This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of tetanus, diphtheria, and pertussis in the United States. As a comprehensive summary of previously published recommendations, this ...

Last Updated: 31 Dec 1969

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Cutaneous Diphtheria.
 

Author(s): Isabel E Wilson, Esse N Menson

Journal: N. Engl. J. Med.. 2018 Mar;378(13):e17.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diphtheria" returned 15 free, full-text review articles on human participants. First 3 results:

Adult vaccination against tetanus and diphtheria: the European perspective.
 

Author(s): B Weinberger

Journal: Clin. Exp. Immunol.. 2017 Jan;187(1):93-99.

 

Besides immunizations against influenza, Streptococcus pneumoniae and herpes zoster, which are recommended specifically for elderly people, regular booster vaccinations against tetanus, diphtheria and in some cases pertussis and polio are recommended in many European countries for ...

Last Updated: 31 Dec 1969

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Corynebacterium ulcerans cutaneous diphtheria.
 

Author(s): Luke S P Moore, Asuka Leslie, Margie Meltzer, Ann Sandison, Androulla Efstratiou, Shiranee Sriskandan

Journal: Lancet Infect Dis. 2015 Sep;15(9):1100-1107.

 

We describe the case of a patient with cutaneous diphtheria caused by toxigenic Corynebacterium ulcerans who developed a right hand flexor sheath infection and symptoms of sepsis such as fever, tachycardia, and elevated C-reactive protein, after contact with domestic cats and dogs, ...

Last Updated: 31 Dec 1969

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Combined hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type B vaccine; Infanrix™ hexa: twelve years of experience in Italy.
 

Author(s): Vincenzo Baldo, Paolo Bonanni, Marcela Castro, Giovanni Gabutti, Elisabetta Franco, Federico Marchetti, Rosa Prato, Francesco Vitale

Journal: Hum Vaccin Immunother. 2014 ;10(1):129-37.

 

Infant vaccination using 2-dose priming at 3 and 5 mo of age with a booster at 11-12 mo of age was pioneered in Italy. The 3-5-11 schedule is now used in a growing number of European countries. Infanrix™ hexa (DTPa-HBV-IPV/Hib, GlaxoSmithKline Vaccines) was first licensed for use ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Heterologous Effect of Diptheria, Tetanus, Acellular Pertussis Vaccination on Influenza Challenge in the Elderly
 

Status: Recruiting

Condition Summary: Heterologous Effects of Vaccines

 

Last Updated: 25 Jul 2017

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A Trial to Evaluate the Safety, Immunogenicity and Effect on Infant Immune Responses of a Single Dose of Tdap in Pregnant Women in Mali
 

Status: Not yet recruiting

Condition Summary: Clostridium Difficile Immunisation; Diphtheria; Diphtheria Immunisation; Pertussis; Tetanus; Tetanus Immunisation

 

Last Updated: 2 Aug 2018

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